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PHARMA EXAM > 6 > Flashcards

6 Flashcards

1
Q

Pair the quinolone carboxylic acid generations with the statement about them:

Generation 1
Generation 2
Generation 3
Generation 4

The alternatives:
1. anti.pseudomonas activity appears
2. anti-streptococcus efficacy is shown
3. their spectrum is narrow, they are effective against gram-negative rods and coliforms
4. anaerobic efficacy is shown

A

Generation 1:their spectrum is narrow, they are effective against gram-negative rods and coliforms

Generation 2: anti.pseudomonas activity appears

Generation 3: anti-streptococcus efficacy is shown

Generation 4:anaerobic efficacy is shown

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2
Q

Pair the anticonvulsant agents with their corresponding statement:

Antiepileptic agent for long-term use, efficacy of it should be evaluated within 2-3 weeks after the initiation of the therapy

The alternatives:
1. Imepitoin
2. KBr
3. Pentobarbital
4. Propofol
5. Phenobarbital

A

phenobabrital

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3
Q

Pair the anticonvulsant agents with their corresponding statement:

antiseptic agent effective as phenobarbital, but with the possible side effect of 3rd eyelid prolapse

The alternatives:
1. Imepitoin
2. KBr
3. Pentobarbital
4. Propofol
5. Phenobarbital

A

imepitoin

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4
Q

Pair the anticonvulsant agents with their corresponding statement:

anticonvulsive agent given in status epilepticus or for performing euthanasia as well

The alternatives:
1. Imepitoin
2. KBr
3. Pentobarbital
4. Propofol
5. Phenobarbital

A

pentobarbital

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5
Q

Pair the anticonvulsant agents with their corresponding statement:

anti epileptic agent for long-term use, it can cause severe respiratory distress in cats

The alternatives:
1. Imepitoin
2. KBr
3. Pentobarbital
4. Propofol
5. Phenobarbital

A

KBr

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6
Q

Pair the anticonvulsant agents with their corresponding statement:

anticonvulsive anaesthetic agent given as IV bolus or continuous rate infusion (CRI)

The alternatives:
1. Imepitoin
2. KBr
3. Pentobarbital
4. Propofol
5. Phenobarbital

A

Propofol

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7
Q

Biofilms can be formed only in inanimate objects

A. True
B. False

A

B. False

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8
Q

pair the active substances to their therapeutical indication(s):

Dopamine

The alternatives:
1.anaphylaxia, cardiac stop, local bleeding
2. urinary incontinence due to poor muscle tone in the urethral sphincter
3. maintenance therapy of RAO, feline asthma
4. antidote for toxicosis caused by alpha 2 receptor agonists
5. Emesis induction, pain reduction, for sedation
6. Acute asthamtic attacks
7. dose-dependent, low dose increases urine output, renal blood flow, medium dose increases cardiac output and high dose can result in pressor effect
8.glaucoma, hypertension
9. Arrhytmia, hypertension

A

dose-dependent, low dose increases urine output, renal blood flow, medium dose increases cardiac output and high dose can result in pressor effect

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9
Q

pair the active substances to their therapeutical indication(s):

salbutamol

The alternatives:
1.anaphylaxia, cardiac stop, local bleeding
2. urinary incontinence due to poor muscle tone in the urethral sphincter
3. maintenance therapy of RAO, feline asthma
4. antidote for toxicosis caused by alpha 2 receptor agonists
5. Emesis induction, pain reduction, for sedation
6. Acute asthamtic attacks
7. dose-dependent, low dose increases urine output, renal blood flow, medium dose increases cardiac output and high dose can result in pressor effect
8.glaucoma, hypertension
9. Arrhytmia, hypertension

A

acute asthmatic attacks

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10
Q

pair the active substances to their therapeutical indication(s):

adrenaline

The alternatives:
1.anaphylaxia, cardiac stop, local bleeding
2. urinary incontinence due to poor muscle tone in the urethral sphincter
3. maintenance therapy of RAO, feline asthma
4. antidote for toxicosis caused by alpha 2 receptor agonists
5. Emesis induction, pain reduction, for sedation
6. Acute asthamtic attacks
7. dose-dependent, low dose increases urine output, renal blood flow, medium dose increases cardiac output and high dose can result in pressor effect
8.glaucoma, hypertension
9. Arrhytmia, hypertension

A

anaphylaxia, cardiac stop, local bleeding

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11
Q

pair the active substances to their therapeutical indication(s):

timolol

The alternatives:
1.anaphylaxia, cardiac stop, local bleeding
2. urinary incontinence due to poor muscle tone in the urethral sphincter
3. maintenance therapy of RAO, feline asthma
4. antidote for toxicosis caused by alpha 2 receptor agonists
5. Emesis induction, pain reduction, for sedation
6. Acute asthamtic attacks
7. dose-dependent, low dose increases urine output, renal blood flow, medium dose increases cardiac output and high dose can result in pressor effect
8.glaucoma, hypertension
9. Arrhytmia, hypertension

A

glucoma, hypertension

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12
Q

pair the active substances to their therapeutical indication(s):

phenylpropanolamine

The alternatives:
1.anaphylaxia, cardiac stop, local bleeding
2. urinary incontinence due to poor muscle tone in the urethral sphincter
3. maintenance therapy of RAO, feline asthma
4. antidote for toxicosis caused by alpha 2 receptor agonists
5. Emesis induction, pain reduction, for sedation
6. Acute asthamtic attacks
7. dose-dependent, low dose increases urine output, renal blood flow, medium dose increases cardiac output and high dose can result in pressor effect
8.glaucoma, hypertension
9. Arrhytmia, hypertension

A

urinary incontinence due to poor muscle tone in the urethral sphincter

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13
Q

pair the active substances to their therapeutical indication(s):

propanolol

The alternatives:
1.anaphylaxia, cardiac stop, local bleeding
2. urinary incontinence due to poor muscle tone in the urethral sphincter
3. maintenance therapy of RAO, feline asthma
4. antidote for toxicosis caused by alpha 2 receptor agonists
5. Emesis induction, pain reduction, for sedation
6. Acute asthamtic attacks
7. dose-dependent, low dose increases urine output, renal blood flow, medium dose increases cardiac output and high dose can result in pressor effect
8.glaucoma, hypertension
9. Arrhytmia, hypertension

A

arrhythmia, hypertension

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14
Q

pair the active substances to their therapeutical indication(s):

atipamezole

The alternatives:
1.anaphylaxia, cardiac stop, local bleeding
2. urinary incontinence due to poor muscle tone in the urethral sphincter
3. maintenance therapy of RAO, feline asthma
4. antidote for toxicosis caused by alpha 2 receptor agonists
5. Emesis induction, pain reduction, for sedation
6. Acute asthamtic attacks
7. dose-dependent, low dose increases urine output, renal blood flow, medium dose increases cardiac output and high dose can result in pressor effect
8.glaucoma, hypertension
9. Arrhytmia, hypertension

A

antidote for toxicosis caused by alpha 2 receptor agonists

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15
Q

pair the active substances to their therapeutical indication(s):

xylazine

The alternatives:
1.anaphylaxia, cardiac stop, local bleeding
2. urinary incontinence due to poor muscle tone in the urethral sphincter
3. maintenance therapy of RAO, feline asthma
4. antidote for toxicosis caused by alpha 2 receptor agonists
5. Emesis induction, pain reduction, for sedation
6. Acute asthamtic attacks
7. dose-dependent, low dose increases urine output, renal blood flow, medium dose increases cardiac output and high dose can result in pressor effect
8.glaucoma, hypertension
9. Arrhytmia, hypertension

A

emesis induction, pain reduction, for sedation

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16
Q

pair the active substances to their therapeutical indication(s):

salmetrol

The alternatives:
1.anaphylaxia, cardiac stop, local bleeding
2. urinary incontinence due to poor muscle tone in the urethral sphincter
3. maintenance therapy of RAO, feline asthma
4. antidote for toxicosis caused by alpha 2 receptor agonists
5. Emesis induction, pain reduction, for sedation
6. Acute asthamtic attacks
7. dose-dependent, low dose increases urine output, renal blood flow, medium dose increases cardiac output and high dose can result in pressor effect
8.glaucoma, hypertension
9. Arrhytmia, hypertension

A

meintance therapy of RAO, feline asthma

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17
Q

pair each agent with the route of administration:

Cloxacilin

benzylpenicillin-procaine/banzatin

benzylpencillin-NA/K

phenoxymethyloenicillin

The alternatives:
1. Mainly udder infusion
2. PO
3. IM/SC
4. IV/IM/SC

A

Cloxacilin: mainly udder infusion

benzylpenicillin-procaine/banzatin: IM/SC

benzylpencillin-NA/K: IV/IM/SC

phenoxymethyloenicillin: PO

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18
Q

Acrolein-caused haemorrhage cystitis can be alleviated by mesna

A. True
B. False

A

A. True

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19
Q

Cats generally tolerate glucocorticoids therapy better than dogs

A. True
B. False

A

A. True

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19
Q

Cats generally tolerate glucocorticoids therapy better than dogs

A. True
B. False

A

A. True

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20
Q

The solution can be administered by a wide variety of routes enterally, parenterally and topically too.

A. True
B. False

A

A. True

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21
Q

Lipophilic solution are recommended for intravenous administration due to their short half-life

A. True
B. False

A

B. False

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22
Q

Gram-negative bacteria are generally more susceptible to tilymicosin than mycoplasmas

A. True
B. False

A

A. True

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23
Q

Pair the substances used un atopic dermatitis with corresponding statement:

the least effective from the listed substances for the treatment of atopic dermatitis, however starting its administration prior to the allergy season might handle the symptoms

The alternatives:
1. Prednisolone
2. Bedinvetmab
3. Hydroxyzin
4. Oclacitinib
5. Lokivetmab

A

hydroxyzin

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24
Q

Pair the substances used un atopic dermatitis with corresponding statement:

applied once parenterally provides long-acting effect

The alternatives:
1. Prednisolone
2. Bedinvetmab
3. Hydroxyzin
4. Oclacitinib
5. Lokivetmab

A

lokivetmab

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25
Q

Pair the substances used un atopic dermatitis with corresponding statement:

used only in chronic cases for long-term treatment due to the delayed onset of action

The alternatives:
1. Prednisolone
2. Bedinvetmab
3. Hydroxyzin
4. Oclacitinib
5. Lokivetmab
6. cyclosporine

A

cyclosporine
La te alternativet siden d mangla

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26
Q

Pair the substances used un atopic dermatitis with corresponding statement:

not used for treatment of atopic dermatitis

The alternatives:
1. Prednisolone
2. Bedinvetmab
3. Hydroxyzin
4. Oclacitinib
5. Lokivetmab

A

bedinvetmab

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27
Q

Pair the substances used un atopic dermatitis with corresponding statement:

anti-inflammatory and in case of long-term application immunosuppressive agent decreasing the levels of IL 2,4,6,13,31

The alternatives:
1. Prednisolone
2. Bedinvetmab
3. Hydroxyzin
4. Oclacitinib
5. Lokivetmab

A

oclacitinib

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28
Q

Pair the substances used un atopic dermatitis with corresponding statement:

effective in acute and chronic cases, can be applied orally, locally and parenterally as well

The alternatives:
1. Prednisolone
2. Bedinvetmab
3. Hydroxyzin
4. Oclacitinib
5. Lokivetmab

A

prednisolone

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29
Q

phenoxymethyl-pencillin is used parenteral in pigs for the treatment of necrotising enteritis caused by clostridium perfringens C

A. True
B. False

A

B. False

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30
Q

of the macrolide group, tulathromycin, gamithromycin, and tildipyrosin have the worst tissue distribution

A. True
B. False

A

B. False

31
Q

Glucocorticoids cause lymphocyte apoptosis

A. True
B. False

A

A. True

32
Q

change in pH value influence the efficacy of strong acid disinfectants, but it does not change the effect of weak acid disinfectants

A. True
B. False

A

B. False

33
Q

Tilvalosin may be used to treat gastrointestinal tract infections caused by Escherichia coli and Salmonella

A. True
B. False

A

B. False

34
Q

Pair the following hormones and hormonal agents with the typical route of administration during veterinary practice:

Lente insulin:
Norgestomet:
Glipizide:
Acarbose:
Buzerelin:
Altrenogest:
hCG (human chronic gonadotropin):
Deslorelin:
Methimazole:

The alternatives:
1. Subcutaneous implant
2. Orally
3. Injection

A

Lente insulin: injection

Norgestomet: subcutaneous implant

Glipizide: orally

Acarbose: orally

Buzerelin: Injection

Altrenogest: Orally

hCG (human chronic gonadotropin):Injection

Deslorelin: Subcutanous implant

Methimazole: Orally

35
Q

cyclophosphamide is an immunosuppressive agent belonging to the group of alkylating agents

A. True
B. False

A

A. True

36
Q

Which of the following drugs is characterised by a spasmolytic effect?

A. Flunixin-meglumine
B. metamizole
C. none
D. all two

A

D. all two

37
Q

Mycophenolate mofetil is an immunosuppressive agent that belongs to the group of alkylating agents

A. True
B. False

A

B. False

38
Q

which of the following is the pharmacological action of NSAIDs?

A. anti-inflammatory
B. antipyretic
C. analgesic
D. all three

A

D. all three

39
Q

Pair the antimicrobial substances use din companion animals to their description:

macrolid antibacterial agent used in combination with metronidazole in oral cavity infections

The alternatives:
1. Florfenicol
2. Neomycin
3. Doxycycline
4. Spiramicin
5. Ronidazole
6. Polimixin-B

A

spiramicin

40
Q

Pair the antimicrobial substances use din companion animals to their description:

primary choice, topically used antibacterial agent in Gr+ otitis externa

The alternatives:
1. Florfenicol
2. Neomycin
3. Doxycycline
4. Spiramicin
5. Ronidazole
6. Polimixin-B

A

florfenicol

41
Q

Pair the antimicrobial substances use din companion animals to their description:

antimicrobial agent used in feline Tritrichomonas infection possibly causing CNS signs as side effects

The alternatives:
1. Florfenicol
2. Neomycin
3. Doxycycline
4. Spiramicin
5. Ronidazole
6. Polimixin-B

A

ronidazole

42
Q

Pair the antimicrobial substances use din companion animals to their description:

antibacterial agent used also for its immunodulatory and anti-inflammatory effect

The alternatives:
1. Florfenicol
2. Neomycin
3. Doxycycline
4. Spiramicin
5. Ronidazole
6. Polimixin-B

A

doxycycline

43
Q

Pair the antimicrobial substances use din companion animals to their description:

aminoglycoside agent used primary topically or orally otherwise given is highly toxic

The alternatives:
1. Florfenicol
2. Neomycin
3. Doxycycline
4. Spiramicin
5. Ronidazole
6. Polimixin-B

A

neomycin

44
Q

Pair the antimicrobial substances use din companion animals to their description:

antibacterial agent used topically in P.aeruginosa otitis externa

The alternatives:
1. Florfenicol
2. Neomycin
3. Doxycycline
4. Spiramicin
5. Ronidazole
6. Polimixin-B

A

polimxin-B

45
Q

it is recommended to monitor monocyte, neutrophil and eosinophil granulocyte counts during long-term oclacitnib therapy

A. True
B. False

A

A. True

46
Q

Lidocaine can be administered orally for long-term therapy

A. True
B. False

A

B. False

47
Q

Disinfectants and antiseptic have more then one target, therefore pathogens are not able to develop resistance against these compounds

A. True
B. False

A

B. False

48
Q

Pair the active substance to the appropriate description:

it can cause hyperglycaemia and it is contraindicated in late pregnancy

The alternatives:
1. Diazepam
2. Phenobarbital
3. Azaperone
4. xylazine
5. Chlorpromazine

A

xylazine

49
Q

Pair the active substance to the appropriate description:

should be used cautiously together with ahminoglycosides

The alternatives:
1. Diazepam
2. Phenobarbital
3. Azaperone
4. xylazine
5. Chlorpromazine

A

diazepam

50
Q

Pair the active substance to the appropriate description:

generally safe agent, but rarely it may cause liver toxicity

The alternatives:
1. Diazepam
2. Phenobarbital
3. Azaperone
4. xylazine
5. Chlorpromazine

A

phenobarbital

51
Q

Pair the active substance to the appropriate description:

contraindicated to used in epileptic and pseudopregnant animals

The alternatives:
1. Diazepam
2. Phenobarbital
3. Azaperone
4. xylazine
5. Chlorpromazine

A

chlorpromazine

52
Q

Pair the active substance to the appropriate description:

in porcine patients optimal outside temperature should be provide to the animal when this drug is administered

The alternatives:
1. Diazepam
2. Phenobarbital
3. Azaperone
4. xylazine
5. Chlorpromazine

A

azaperone

53
Q

Pair the active ingredient to the appropriate description:

Narrow spectrum antiparasitic, active against all stages of liver fluke

The alternatives:
1. Albendazole
2. closantel
3. Ivermectin
4. Levamisole
5.Triclabendazole

A

Triclabendazole

54
Q

Pair the active ingredient to the appropriate description:

Macrocyclic lactone, acrobate against nematodes and ectoparasites

The alternatives:
1. Albendazole
2. closantel
3. Ivermectin
4. Levamisole
5.Triclabendazole

A

Ivermectin

55
Q

Pair the active ingredient to the appropriate description:

among nematodes this antiparasitic agent is active only against bloodsucking worms

The alternatives:
1. Albendazole
2. closantel
3. Ivermectin
4. Levamisole
5.Triclabendazole

A

closantel

56
Q

Pair the active ingredient to the appropriate description:

it is a broad spectrum antiparasitic agent, active against Nematoda, Cestoda, and Trematoda

The alternatives:
1. Albendazole
2. closantel
3. Ivermectin
4. Levamisole
5.Triclabendazole

A

Albendazole

57
Q

Pair the active ingredient to the appropriate description:

antiparasitic agent effective only against nematodes

The alternatives:
1. Albendazole
2. closantel
3. Ivermectin
4. Levamisole
5.Triclabendazole

A

Levamisole

58
Q

Pair the active ingredient to the appropriate description:

Na-channel blocker antiparasitic agent effective only against fleas

The alternatives:
1. Amitraz
2. Indoxacarb
3. Moxidectin
4. Couamphos
5. Deltamethrin

A

indoxacarb

59
Q

Pair the agents used against ectoparasites to their description:

contact poison antiparasitic agent with repellent

The alternatives:
1. Amitraz
2. Indoxacarb
3. Moxidectin
4. Couamphos
5. Deltamethrin

A

deltamethrin

60
Q

Pair the agents used against ectoparasites to their description:

Glu-mediated chloride-ion channel and GABA-antagonist antiparasitic agent given orally

The alternatives:
1. Amitraz
2. Indoxacarb
3. Moxidectin
4. Couamphos
5. Deltamethrin
6. Lotilaner

A

lotilaner

61
Q

Pair the agents used against ectoparasites to their description:

Monoamino-oxidase inhibitor antiparasitic agent

The alternatives:
1. Amitraz
2. Indoxacarb
3. Moxidectin
4. Couamphos
5. Deltamethrin

A

amitraz

62
Q

Pair the agents used against ectoparasites to their description:

irreversible inhibitor of acetylcholine aesterase

The alternatives:
1. Amitraz
2. Indoxacarb
3. Moxidectin
4. Couamphos
5. Deltamethrin

A

coumaphos

63
Q

Pair the agents used against ectoparasites to their description:

Glu-mediated Chloride-ion channel and GBA-agonist antiparasitic agent given also topically

The alternatives:
1. Amitraz
2. Indoxacarb
3. Moxidectin
4. Couamphos
5. Deltamethrin

A

moxidectin

64
Q

which is the first choice antibiotic for treatment of Lawsonia intracellular proliferative enteropathy in foals?

The alternatives:
A. amoxicillin
B. enrofloaxacin
C. doxycycline
D. tiamulin

A

C. doxycycline

65
Q

mexiletine should be administered intravenously

A. True
B. False

A

B. False

66
Q

A typical side effect of glucocorticoid therapy is loss of appetite

A. True
B. False

A

B. False

67
Q

pair the substances used for stomach ulcer prevention and treatment to their corresponding statements:

If used for more than 3-4 weeks due to rebound effect administration must be dyscontinued gradually

The alternatives:
1. Aluminium hydroxide
2. Cimetidine
3. Omeprazole
4. Misoprostol
5. Famotidine

A

omeprazole

68
Q

pair the substances used for stomach ulcer prevention and treatment to their corresponding statements:

Degraded by the stomach juice, bound to the damaged mucosa of the stomach wall, less suitable for the treatment of gastric ulceration but rather suitable for binding phosporus

The alternatives:
1. Aluminium hydroxide
2. Cimetidine
3. Omeprazole
4. Misoprostol
5. Famotidine

A

aluminium-hydroxide

69
Q

pair the substances used for stomach ulcer prevention and treatment to their corresponding statements:

H2-antagonist used in cats long-term every other day (ADT)

The alternatives:
1. Aluminium hydroxide
2. Cimetidine
3. Omeprazole
4. Misoprostol
5. Famotidine

A

fematidine

70
Q

pair the substances used for stomach ulcer prevention and treatment to their corresponding statements:

Possible, but not effective antidote for acetaminophen (paracetamol) toxicosis, CYP enzyme inhibitor, not frequently used H2- antagonist

The alternatives:
1. Aluminium hydroxide
2. Cimetidine
3. Omeprazole
4. Misoprostol
5. Famotidine

A

cimetidine

71
Q

pair the substances used for stomach ulcer prevention and treatment to their corresponding statements:

PGE-analogue used exclusively for the prevention of gastric ulcer induced by NSAID’s

The alternatives:
1. Aluminium hydroxide
2. Cimetidine
3. Omeprazole
4. Misoprostol
5. Famotidine

A

misoprostol

72
Q

which of the following agents is characterised by low absorption after oral administration in pigs?

A. colistin
B. florfenicol
C. tiamulin
D. enrofloaxcin

A

A. colistin

73
Q

Olactinib primarily inhibits the enzyme JAK-2

A. True
B. False

A

B. False

74
Q

Give the order of disappearance of nervous function after local anaesthetic administration:

  • deep pressure
  • motor function
  • pain
  • warmth
  • touch
A
  • deep pressure: 4
  • motor function: 5
  • pain: 1
  • warmth: 2
  • touch: 3
75
Q

olacitinib is very wall absorbed after per os administration

A. True
B. False

A

A. True

PHARMA EXAM (6 decks)

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