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PHARMA EXAM > 2 > Flashcards

2 Flashcards

1
Q

The side chains of beta lactams antibiotics are responsoble for …

A. None of them
B. the spectrum of the antibiotic
C. both
D. the pharmacokinetic properties of the antibiotic

A

both

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2
Q

Antiparasitic agent licensed for oral use in poultry against bird mites (Dermanissus gallinae)

A. Deltamethrin
B. Moxidectin
C. Fluralaner
D. fypronil

A

c. fluralaner

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3
Q

Against which of the following pathogens are aminoglycosides not effective?

A. Salmonella spp
B. Streptococcus spp
C. E.coli
D. Staphylococcus spp

A

streptococcus

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4
Q

in status epilepticus, levetiracetam may be used intravenously or rectally

A. True
B. False

A

A. True

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5
Q

tiletamine belongs to the group of nmda receptor antagonists called dissociative anesthetics

A. True
B. False

A

A. True

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6
Q

which of the following substances has sedatohypnotic effect?

A. Xylazine
B. Romifidine
C. Medetomidine
D. None of them
E. All of them

A

all of them

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7
Q

isoflurane is an injectable anesthetic

A. True
B. False

A

B. False

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8
Q

the competitive antagonist of 3 beta hydroxysteroid dehydrogenase enzyne

A. Cabergoline
B. Trilostan
C. Denaverin
D. Terbutalin

A

Trilostan

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9
Q

clopidogrel should not be used in cats only dogs

A. True
B. False

A

B. False

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10
Q

which of the following has a marked inhibitory effect on t cells

A. Tacrolimus
B. Lokivetmab
C. sulfasalazine
D. Oclacitinib

A

tacrolimus

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11
Q

which of the following substances can cause azotemia

A. None of them
B. Both of them
C. Enalapril
D. Lisinopril

A

d. both

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12
Q

which of the following drugs can be effective in Moraxella bovis keratoconjunctivitis?

A. None of them
B. Both of them
C. Chlortetracycline
D. Florfenicol

A

b. both

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13
Q

pair agents

juvenile hormone analogue antiparasitic

  • Afoxolaner
  • Fipronil
  • Metopren
  • imidacloprid
  • fluralaner
  • piriprol
A

Metopren

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14
Q

pair agents

Gaba antagonist antiparasitic agent not recommended to use in rabbits

  • Afoxolaner
  • Fipronil
  • Metopren
  • imidacloprid
  • fluralaner
  • piriprol
A

Fipronil

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15
Q

pair agents

Izoxazoline eliminated by the kidney

  • Afoxolaner
  • Fipronil
  • Metopren
  • imidacloprid
  • fluralaner
  • piriprol
A

Afoxolaner

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16
Q

pair agents

Antiparasitic agent only effective against fleas

  • Afoxolaner
  • Fipronil
  • Metopren
  • imidacloprid
  • fluralaner
  • piriprol
A

imidacloprid

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17
Q

pair agents

Antiparasitic agent with relative longer elimination half-life due to enterohepatic circulation

  • Afoxolaner
  • Fipronil
  • Metopren
  • imidacloprid
  • fluralaner
  • piriprol
A

fluralaner

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18
Q

pair agents

Gaba antagonist agent effective against tics and fleas in case of 3-10 times overdose CNS signs can occur

  • Afoxolaner
  • Fipronil
  • Metopren
  • imidacloprid
  • fluralaner
  • piriprol
A

piriprol

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19
Q

Orthosteric agonist binds to the receptor at the same place where its ligand binds while allosteric agonist binds to a different site.

A. True
B. False

A

A. True

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20
Q

Pairs

Methylxanthine with weakest direct cardiac effect

  • Caffeine
  • theophylline
  • strychnine
  • Doxapram
  • picrotoxin
A

Caffeine

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21
Q

Pairs

Antidote for gaba ergic cns depressants

  • Caffeine
  • theophylline
  • strychnine
  • Doxapram
  • picrotoxin
A

picrotoxin

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22
Q

Pairs

Short acting respiratory stimulant

  • Caffeine
  • theophylline
  • strychnine
  • Doxapram
  • picrotoxin
A

Doxapram

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23
Q

Pairs

Inhibits phosphodiesterase enzyme and it is a potent bronchodilator, can be used in the treatment of asthma

  • Caffeine
  • theophylline
  • strychnine
  • Doxapram
  • picrotoxin
A

theophylline

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24
Q

Pairs

Glicine antagonist that causes severe convulsions

  • Caffeine
  • theophylline
  • strychnine
  • Doxapram
  • picrotoxin
A

strychnine

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25
Q

Benzyl penicillin Na/K has an average duration of action 4-6 hours

A. True
B. False

A

A. True

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26
Q

Carprofen is safe for use in most mammalian animals

A. True
B. False

A

A. True

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27
Q

Meloxicam injection for swine 100 kg if dose is 0.4 mg/kg and concentration is 20mg/mg

A. 100ml
B. 10ml
C. 2 ml
D. 40ml

A

c. 2 ml

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28
Q

Pair

Locally and systematically applied allylamine derivative

The alternatives:
1. Naftifine
2. Amphotereicin-B
3. Itraconazole
4. Clotriamazole
5. Terbinafin

A

terbinafine

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29
Q

Pair

Locally applied imidazole derivative

The alternatives:
1. Naftifine
2. Amphotereicin-B
3. Itraconazole
4. Clotriamazole
5. Terbinafin

A

clotrimazole

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30
Q

Pair

Systemically applied imidazole derivative

The alternatives:
1. Naftifine
2. Amphotereicin-B
3. Itraconazole
4. Clotriamazole
5. Terbinafin

A

itraconazole

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31
Q

Pair

Parentally applied polyene

The alternatives:
1. Naftifine
2. Amphotereicin-B
3. Itraconazole
4. Clotriamazole
5. Terbinafin

A

amphotericin-b

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32
Q

Pair

Locally applied allylamine derivative

The alternatives:
1. Naftifine
2. Amphotereicin-B
3. Itraconazole
4. Clotriamazole
5. Terbinafin

A

Naftifine

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33
Q

put the local anaesthetics according to their toxicity in increased order:
Procaine , Mepivacaine
Bupivacaine, Lidocaine

A

Procaine -1
Lidocaine -2
Mepivacaine 3
Bupivacaine 4

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34
Q

Side effects of glucocorticoids include muscle hypertrophy, increased calcium absorption and collagen synthesis

A. True
B. False

A

B. False

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35
Q

Despite the excellent distribution of lincomycin it does not cross the BBB

A. True
B. False

A

A. True

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36
Q

Acrolein hemorrhagic cystitis can be alleviated by Mensa

A. True
B. False

A

A. True

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37
Q

Aminoglycosides are positively charged, cationic polar and hydrophilic compounds

A. True
B. False

A

A. True

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38
Q

EPO can treat anemia because of chronic kidney failure or cancer only after hematocrit level determination

A. True
B. False

A

A. True

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39
Q

Pairs

_____anti-inflammatory drug used in milder cases of corneal ulcers

The alternatives:
1. Azelastine
2. Prednisolone
3. Sodium chromoglycate
4. Bromfenac
5. Atropine

A

Bromfenac

40
Q

_____ can inhibit the formation of synechia in uveitis

The alternatives:
1. Azelastine
2. Prednisolone
3. Sodium chromoglycate
4. Bromfenac
5. Atropine

A

Atropine

41
Q

_____ anti-inflammatory drug used inn uveitis if cornea is intact

The alternatives:
1. Azelastine
2. Prednisolone
3. Sodium chromoglycate
4. Bromfenac
5. Atropine

A

Prednisolone

42
Q

_____ mast cell stabilizers used in allergic conjunctivitis

The alternatives:
1. Azelastine
2. Prednisolone
3. Sodium chromoglycate
4. Bromfenac
5. Atropine

A

Sodium chromoglycate

43
Q

_____antihistamine used inn allergic conjunctivitis

The alternatives:
1. Azelastine
2. Prednisolone
3. Sodium chromoglycate
4. Bromfenac
5. Atropine

A

Azelastine

44
Q

Which of the following agents are suitable for the treatment of enteritis caused by clostridia?

A. Vancomycin
B. Both
C. Neither
D. Bacitracin

A

both

45
Q

The antimicrobial spectrum off azithromycin and clarithromycin includes staphylococcus and streptococci

A. True
B. False

A

A. True

46
Q

A higher therapeutic index means that the drug can easily be overdosed

A. True
B. False

A

B. False

47
Q

First generation quinolone carboxylic acids have narrow spectrum and are effective against gram negative rods and coliforms

A. True
B. False

A

A. True

48
Q

Pus and debris greatly impact the effectiveness of sulfonamides

A. True
B. False

A

A. True

49
Q

Diazepam can cause paradoxical reaction inn cats

A. True
B. False

A

A. True

50
Q

70- 80% isotonic crystalloid infusion are distributed in IV fluid compartment

A. True
B. False

A

B. False

51
Q

Idoxuridine can be used locally to treat herpes virus caused keratitis in cats

A. True
B. False

A

A. True

52
Q

Pseudomonas aerginosus is highly sensitive to florfenicol

A. True
B. False

A

B. False

53
Q

Pairs

Biguanidine disinfectant

The alternatives:
1. Pocidone iodine
2. Hydrogen peroxide
3. Calcium hydroxide
4. Quaternary ammonium compound
5. Chlorhexide

A

Chlorhexidine

54
Q

Pairs

Cationic detergents

The alternatives:
1. Pocidone iodine
2. Hydrogen peroxide
3. Calcium hydroxide
4. Quaternary ammonium compound
5. Chlorhexide

A

quarternary ammonium compound

55
Q

Pairs

Halogen containing disinfectant

The alternatives:
1. Povione iodine
2. Hydrogen peroxide
3. Calcium hydroxide
4. Quaternary ammonium compound
5. Chlorhexide

A

povione Iodine

56
Q

Pairs

Oxidizing agent

The alternatives:
1. Pocidone iodine
2. Hydrogen peroxide
3. Calcium hydroxide
4. Quaternary ammonium compound
5. Chlorhexide

A

hydrogen peroxide

57
Q

Pairs

Belongs to the alkalis disinfectants

The alternatives:
1. Pocidone iodine
2. Hydrogen peroxide
3. Calcium hydroxide
4. Quaternary ammonium compound
5. Chlorhexide

A

calcium hydroxide

58
Q

The lower the therapeutic index of an active substance the closer its ED50 is to LD50 value

A. True
B. False

A

A. True

59
Q

Primary choice cephalosporine to treat canine pyoderma systemically

A. Cefotaxime
B. Cefoperazone
C. Cephalexin
D. Cefquinome

A

Cephalexin

60
Q

Which side effect is specific to fluoroquinolones?

A

a. Inhibition of growth of cartilage in young animals

61
Q

In case of transformation the resistance gene is transmitted by a bacteriophage

A. True
B. False

A

B. False

in case of transduction!

62
Q

Short acting tetracyclines should be administrated once daily orally and long acting should be administered every 2 days

A. True
B. False

A

B. False

63
Q

Anti-inflammatory effects of glucocorticoids can only be achieved in high dose

A. True
B. False

A

B. False

64
Q

Prostaglandin E increases mucin secretion in gastric mucosa

A. True
B. False

A

A. True

65
Q

In fish WP is determined in degree days which is the cumulative sum of daily water temperature

A. True
B. False

A

A. True

66
Q

Tiamulin is a concentration dependent bactericidal antibacterial agent

A. True
B. False

A

B. False

Bacteriostatic

67
Q

Azepromazine can be used handling aggressive animals

A. True
B. False

A

A. True

68
Q

Dembrexin is used for feline asthma

A. True
B. False

A

B. False

69
Q

In status epilepticus propofol is administrated intramuscularly

A. True
B. False

A

B. False

IV

70
Q

Antibiotic resistance genes encoded on chromosomes have a bigger impact on the spread of the resistance compared to genes on plasmids

A. True
B. False

A

B. False

71
Q

In which of the following conditons is the use of oclatinib contraindicated

A. Both
B. None
C. Noncancerous diseases
D. Demodicosis

A

Both

72
Q

Which of the following effects are considered to be adverse effects of drugs

A. Toxic metabolite formation
B. Damaging immune response
C. idosyncratic response
D. All three

A

All three

73
Q

Pairs

Gram positive mastitis

The alternatives:
1. Ceftriaxone
2. Cefoperazone
3. Cefovecin
4. Cefapirin

A

cefapirin

74
Q

Pairs

Gram negative mastitis

The alternatives:
1. Ceftriaxone
2. Cefoperazone
3. Cefovecin
4. Cefapirin

A

cefoperazone

75
Q

Pairs

Meningitis

The alternatives:
1. Ceftriaxone
2. Cefoperazone
3. Cefovecin
4. Cefapirin

A

ceftriaxone

76
Q

Pairs

UTI

The alternatives:
1. Ceftriaxone
2. Cefoperazone
3. Cefovecin
4. Cefapirin

A

cefovecin

77
Q

Agent used for long term management phonophobia:

A. Acepromazine
B. Clomipramine
C. Selegiline
D. Cefovecin

A

Clomipramine

78
Q

The MAO selegilin can be used in dogs to slow down the progression of old age dementia

A. True
B. False

A

A. True

79
Q

How much 40% glucose solution is needed to prepare 100 ml 5% solution?

A. 25ml
B. 50ml
C. 12.5 ml
D. 75ml

A

12.5ml

80
Q

which of the following substances have a bronchodilator effect?

A. Anticholinergic drugs
B. Sympathomimetics
C. Xanthine derivatives
D. All of them
E. None of them

A

All of them

81
Q

which of the following can reduce high blood pressure?

A. Both of them
B. None of them
C. ATII receptor anatgonists
D. ACE inhibitors

A

all of them

82
Q

Pairs

monovalent ionophore coccidiostat

The alternatives:
1. Toltrazuril
2. Lazalocid
3. Salinomycin
4. Maduramycin
5. Diclazuril

A

salinomycin

83
Q

Pairs

Triazine coccidiostat for use in chemophylaxis via feed

The alternatives:
1. Toltrazuril
2. Lazalocid
3. Salinomycin
4. Maduramycin
5. Diclazuril

A

diclazuril

84
Q

Pairs

semidivalent ionophore coccidiostat

The alternatives:
1. Toltrazuril
2. Lazalocid
3. Salinomycin
4. Maduramycin
5. Diclazuril

A

maduramycin

85
Q

Pairs

active substance for the treatment if coccidiosos via drinking water

The alternatives:
1. Toltrazuril
2. Lazalocid
3. Salinomycin
4. Maduramycin
5. Diclazuril

A

toltrazuril

86
Q

divalent ionophore coccidiostst

The alternatives:
1. Toltrazuril
2. Lazalocid
3. Salinomycin
4. Maduramycin
5. Diclazuril

A

lazalocid

87
Q

Hes infusions with higher average molecular weight have a longer half life, however the risk off liver side effects is also higher in case of them

A. True
B. False

A

B. False

88
Q

Atropine can be used in case of uveitis and organophosphate toxicosis

A. True
B. False

A

A. True

89
Q

Generally if the drug has high affinity to the receptor, higher dose is needed and the drugs effect develops slowly

A. True
B. False

A

B. False

90
Q

Only ionized drugs can cross biological membranes’ by diffusion

A. True
B. False

A

B. False

91
Q

Pairs

Used in dogs, applied in conjuctivital sack, non readministtered opiod emetic agent

The alternatives:
1. Apomorphine
2. Maropitant
3. Hydrogen-peroxide
4. Metoclopramide
5. Ropinirole
6. Xylazine

A

apomorphine

92
Q

Pairs

Antiemetic agent, antidote for the side effect of ropinirole

The alternatives:
1. Apomorphine
2. Maropitant
3. Hydrogen-peroxide
4. Metoclopramide
5. Ropinirole
6. Xylazine

A

metoclopramide

93
Q

Pairs

Peripheral emetic agent acting as irritant on the pharyngeal and stomach mucosa

The alternatives:
1. Apomorphine
2. Maropitant
3. Hydrogen-peroxide
4. Metoclopramide
5. Ropinirole
6. Xylazine

A

hydrogen peroxide

94
Q

Pairs

Used in dogs, applied in conjuctivital sack, readministerable dopamine-agonist agent

The alternatives:
1. Apomorphine
2. Maropitant
3. Hydrogen-peroxide
4. Metoclopramide
5. Ropinirole
6. Xylazine

A

ropinirole

95
Q

Pairs

The most potent antiemetic applied IV in small animal practice

The alternatives:
1. Apomorphine
2. Maropitant
3. Hydrogen-peroxide
4. Metoclopramide
5. Ropinirole
6. Xylazine

A

maropitant

96
Q

Pairs

Used in cats applied IV or IM emetic agent

The alternatives:
1. Apomorphine
2. Maropitant
3. Hydrogen-peroxide
4. Metoclopramide
5. Ropinirole
6. Xylazine

A

xylazine

97
Q

Long acting sympathomimetics are mainly used for diagnostic ophthalmic purposes

A. True
B. False

A

B. False

PHARMA EXAM (6 decks)

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