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PHARMA EXAM > 4 > Flashcards

4 Flashcards

1
Q

Acrolein-caused haemorrhagic cystitis can be alleviated by mesna.

  • True
  • False
A
  • True
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2
Q

Pair the substances used in constipation and diarrhoea to their correpsponding statements:

Decreases the absorption of fat-soluble vitamins

The alternatives:
1. MgSO4
2. Tannic acid
3. Loperamide
4. Undigestable fibres
5. Liquid paraffin
6. Lactulose

A

Liquid paraffin

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3
Q

Pair the substances used in constipation and diarrhoea to their correpsponding statements:

GI tract motility increaser used in irritable bowel syndrome (IBS), crossing the BBB:

The alternatives:
1. MgSO4
2. Tannic acid
3. Loperamide
4. Undigestable fibres
5. Liquid paraffin
6. Lactulose

A

Loperamide

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4
Q

Pair the substances used in constipation and diarrhoea to their correpsponding statements:

Adstringent, vasoconstrictor antidiarrheal agent

The alternatives:
1. MgSO4
2. Tannic acid
3. Loperamide
4. Undigestable fibres
5. Liquid paraffin
6. Lactulose

A

tannic acid

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5
Q

Pair the substances used in constipation and diarrhoea to their correpsponding statements:

Diuretic used primerally in non-dehidrated large animals having ad libitum drinking water supply

The alternatives:
1. MgSO4
2. Tannic acid
3. Loperamide
4. Undigestable fibres
5. Liquid paraffin
6. Lactulose

A

MgSO4

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6
Q

Pair the substances used in constipation and diarrhoea to their correpsponding statements:

Osmotic diuretic used also in hepatic encephalopathy, administered orally or per rectum

The alternatives:
1. MgSO4
2. Tannic acid
3. Loperamide
4. Undigestable fibres
5. Liquid paraffin
6. Lactulose

A

Lactulose

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7
Q

Pair the substances used in constipation and diarrhoea to their correpsponding statements:

Expanded due to absorption of moisture mechanically increases the motility of the GI tract helping passing the stool

The alternatives:
1. MgSO4
2. Tannic acid
3. Loperamide
4. Undigestable fibres
5. Liquid paraffin
6. Lactulose

A

Undigestable fibres

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8
Q

The distribution of diaminopyrimidines in the body is very poor, they do not cross biological membranes

  • True
  • False
A
  • False
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9
Q

Which statement is true about opioids ?

A. They act only in the dorsal horn of the spinal cord, where the sensory nerves are switched.

B. They act at three sites: supraspinal, spinal and peripheral.

C. They act only supraspinally.

D. Act only peripherally, at the site of pain.

A

B. They act at three sites: supraspinal, spinal and peripheral.

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10
Q

Which statement is true?

A. All three

B. Opioids act at the site of nociception.

C. Opioids have a very good analgesic effect.

D. Opioids have antidiarrheal and cough suppressant effects

A

A. All three

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11
Q

Which of the statements is TRUE for Monobactams?

A. Extremely resistant to Gram-negative beta-lactamases, but ineffective against Gram- positive bacteria.

B. All Three.

C. They are classified as AMEG “A”

D. Aztreonam can only be administered parenterally, tigemonam can be administered per os

A

B. All Three.

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12
Q

Tulathromycin and gamithromycin are effective against anaerobic bacteria, making them suitable for the treatment of foot-end infections in ruminants.

A. True
B. False

A

A. True

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13
Q

Pair the active substances to their mechanisms of action!

dicoumarol derivatives

The alternatives:
1. Antagonist of coumarin derivatives
2. ADP receptor inhibitors
3. Antidote for heparin
4. disturbances in synthesis of a few blood clotting factors
5. COX inhibitors
6. Antithrombin activators

A

→ disturbances in synthesis of a few blood clotting factors

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14
Q

Pair the active substances to their mechanisms of action!

vitamin K

The alternatives:
1. Antagonist of coumarin derivatives
2. ADP receptor inhibitors
3. Antidote for heparin
4. Disturbance of a few blood clotting factors
5. COX inhibitors
6. Antithrombin activators

A

→ antagonist of coumarin derivatives

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15
Q

Pair the active substances to their mechanisms of action!

dalteparine

The alternatives:
1. Antagonist of coumarin derivatives
2. ADP receptor inhibitors
3. Antidote for heparin
4. Disturbance of a few blood clotting factors
5. COX inhibitors
6. Antithrombin activators

A

→ antithrombin activators

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16
Q

Pair the active substances to their mechanisms of action!

clopidogrel

The alternatives:
1. Antagonist of coumarin derivatives
2. ADP receptor inhibitors
3. Antidote for heparin
4. Disturbance of a few blood clotting factors
5. COX inhibitors
6. Antithrombin activators

A

→ ADP receptor inhibitors

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17
Q

Pair the active substances to their mechanisms of action!

protamine

The alternatives:
1. Antagonist of coumarin derivatives
2. ADP receptor inhibitors
3. Antidote for heparin
4. Disturbance of a few blood clotting factors
5. COX inhibitors
6. Antithrombin activators

A

→ antidote for heparin

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18
Q

Pair the active substances to their mechanisms of action!

heparin

The alternatives:
1. Antagonist of coumarin derivatives
2. ADP receptor inhibitors
3. Antidote for heparin
4. Disturbance of a few blood clotting factors
5. COX inhibitors
6. Antithrombin activators

A

→ antithrombin activators

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19
Q

Pair the active substances to their mechanisms of action:

acetylsalicylic acid

The alternatives:
1. Antagonist of coumarin derivatives
2. ADP receptor inhibitors
3. Antidote for heparin
4. Disturbance of a few blood clotting factors
5. COX inhibitors
6. Antithrombin activators

A

→ COX inhibitors

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20
Q

Pair the active substances to the appropriate description

It is used in feline hyperthyroidism

The alternatives:
1. Levothyroxime
2. Methimazole
3. Fludrocortisone acetate
4. Insulin
5. Trilostane

A

→ Methimazole

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21
Q

Pair the active substances to the appropriate description

It is used in hyperadrenocorticism

The alternatives:
1. Levothyroxime
2. Methimazole
3. Fludrocortisone acetate
4. Insulin
5. Trilostane

A

→ Trilostane

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22
Q

Pair the active substances to the appropriate description

It is used in Addison’s disease

The alternatives:
1. Levothyroxime
2. Methimazole
3. Fludrocortisone acetate
4. Insulin
5. Trilostane

A

→ Fludrocortisone acetate

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23
Q

Pair the active substances to the appropriate description

As side effects it may cause hypoglycaemia

The alternatives:
1. Levothyroxime
2. Methimazole
3. Fludrocortisone acetate
4. Insulin
5. Trilostane

A

→ Insulin

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24
Q

Pair the active substances to the appropriate description

It is used in hypothyroidism

The alternatives:
1. Levothyroxime
2. Methimazole
3. Fludrocortisone acetate
4. Insulin
5. Trilostane

A

→ Levothyroxine

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25
Q

Lidocaine causes pronounced Vasodilation

A True
B. False

A

B. False

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26
Q

Which AMEG category do the 3-4th generation cephalosporins fall into?

A. “C”
B. “D”
C. “A”
D. “B”

A

D. “B”

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27
Q

Pair the antimicrobial substances used in companion animals to their description

Given also in canine Isospora canis infection

The alternatives:
1. Doxycycline
2. sulfamethoxazole trimethoprim
3. Cefovecin
4. Amoxicillin clavulanic acid
5. Enrofloxacin

A

→ sulfamethoxazole trimethoprim

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28
Q

Pair the antimicrobial substances used in companion animals to their description

Primary choice of drug in Borrelia burgdorferi infection

The alternatives:
1. Doxycycline
2. sulfamethoxazole trimethoprim
3. Cefovecin
4. Amoxicillin clavulanic acid
5. Enrofloxacin

A

→ doxycycline

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29
Q

Pair the antimicrobial substances used in companion animals to their description

Primary choice of drug in canine bacterial prostatitis

The alternatives:
1. Doxycycline
2. sulfamethoxazole trimethoprim
3. Cefovecin
4. Amoxicillin clavulanic acid
5. Enrofloxacin

A

→ enrofloxacin

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30
Q

Pair the antimicrobial substances used in companion animals to their description

The veterinary formulation of the substance is given PO, SC, IM for UTI and pyoderma cases. Covers anaerobic bacteria as well

The alternatives:
1. Doxycycline
2. sulfamethoxazole trimethoprim
3. Cefovecin
4. Amoxicillin clavulanic acid
5. Enrofloxacin

A

→ amoxicillin clavulanic-acid

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31
Q

Pair the antimicrobial substances used in companion animals to their description

Given SC for oral cavity infections with 10-14 days of duration of action

The alternatives:
1. Doxycycline
2. sulfamethoxazole trimethoprim
3. Cefovecin
4. Amoxicillin clavulanic acid
5. Enrofloxacin

A

→ cefovecin

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32
Q

Side effect of doxorubicin treatment can be cardiotoxicity:

A. True
B. False

A

A. True

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33
Q

Which of the following side effects are typical of phenicols?

A. Yellow discoloration of bones
B. Explicit kidney damage
C. Photosensitization
D. Anaemia, immunosuppression

A

D. Anaemia, immunosuppression

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34
Q

Which statement is true about opioids?

A. They exert their powerful analgesic effect through the mu receptors.

B. They cause bradycardia as a side effect via the delta receptors.

C. They cause obstipation as a side effect through kappa receptors via inhibition of the myenteric plexus

D. A their antitussive effects are exerted through the kappa receptors.

A

A. They exert their powerful analgesic effect through the mu receptors.

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35
Q

Which drug would you use to treat anaplasmal infections in dogs?

A. Neomycin
B. Amoxicillin
C. Doxicillin
D. Bacitracin

A

C. Doxicillin

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36
Q

Pair the liquid dose forms with the descriptions of them

its solute is only solid

The alternatives:
1. Suspension
2. Emulsion
3. Solution

A

→ suspension

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37
Q

Pair the liquid dose forms with the descriptions of them

heterogeneous disperse, its precipitate is solid

The alternatives:
1. Suspension
2. Emulsion
3. Solution

A

→ suspension

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38
Q

Pair the liquid dose forms with the descriptions of them

heterogeneous disperse, its precipitate is liquid

The alternatives:
1. Suspension
2. Emulsion
3. Solution

A

→ emulsion

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39
Q

Pair the liquid dose forms with the descriptions of them

its solute is only liquid

The alternatives:
1. Suspension
2. Emulsion
3. Solution

A

→ emulsion

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40
Q

Pair the liquid dose forms with the descriptions of them

homogeneous disperse, it has no precipitate

The alternatives:
1. Suspension
2. Emulsion
3. Solution

A

→ solution

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41
Q

Pair the liquid dose forms with the descriptions of them

its solute can be solid/liquid/gas

The alternatives:
1. Suspension
2. Emulsion
3. Solution

A

→ solution

42
Q

Which of the following aminoglycoside active substances is typically used as an eye drop?

A. apramycin
B. paromomycin
C. spectinomycin
D. tobramycin

A

D. tobramycin

43
Q

Pair the active substance to the appropriate description

Allosteric activator of GABA(A)

The alternatives:
1. Detomidine
2. Midazolam
3. Xylazine
4. Azaperone
5. Atipamezole

A

→ Midazolam

44
Q

Pair the active substance to the appropriate description

Alpha-2-antagonist

The alternatives:
1. Detomidine
2. Midazolam
3. Xylazine
4. Azaperone
5. Atipamezole

A

→ Atipamezole

45
Q

Pair the active substance to the appropriate description

This tranquilizer is not appropriate for oral use

The alternatives:
1. Detomidine
2. Midazolam
3. Xylazine
4. Azaperone
5. Atipamezole

A

→ Azaperone

46
Q

Pair the active substance to the appropriate description

Potent alpha-2 agonist licensed also for equine use

The alternatives:
1. Detomidine
2. Midazolam
3. Xylazine
4. Azaperone
5. Atipamezole

A

→ Detomidine

47
Q

Pair the active substance to the appropriate description

Alpha-2-agonist sedative and also a potent emetic agent in cats

The alternatives:
1. Detomidine
2. Midazolam
3. Xylazine
4. Azaperone
5. Atipamezole

A

→ Xylazine

48
Q

. What are the side effects of polymyxins?

A. neurotoxicity via flaccid paralysis
B. nephrotoxicity
C. none of these
D. Both

A

D. Both

49
Q

Pair the active substances to their categories!

clenbuterole

The alternatives:
1. Methylxanthine derivatives
2. sympathomimetics
3. Leukotriene receptor antagonists
4. Chromones
5. Leukotriene synthesis inhibitor
6. Glucocorticoids
7. Parasympathomimetics

A

→ sympathomimetics

50
Q

Pair the active substances to their categories!

aminophylline

The alternatives:
1. Methylxanthine derivatives
2. sympathomimetics
3. Leukotriene receptor antagonists
4. Chromones
5. Leukotriene synthesis inhibitor
6. Glucocorticoids
7. Parasympathomimetics

A

→ methylxanthine derivatives

51
Q

Pair the active substances to their categories!

zafirlukast

The alternatives:
1. Methylxanthine derivatives
2. sympathomimetics
3. Leukotriene receptor antagonists
4. Chromones
5. Leukotriene synthesis inhibitor
6. Glucocorticoids
7. Parasympathomimetics

A

→ leukotriene receptor antagonists

52
Q

Pair the active substances to their categories!

beclomethasone

The alternatives:
1. Methylxanthine derivatives
2. sympathomimetics
3. Leukotriene receptor antagonists
4. Chromones
5. Leukotriene synthesis inhibitor
6. Glucocorticoids
7. Parasympathomimetics

A

→ glucocorticoids

53
Q

Pair the active substances to their categories!

zileuton

The alternatives:
1. Methylxanthine derivatives
2. sympathomimetics
3. Leukotriene receptor antagonists
4. Chromones
5. Leukotriene synthesis inhibitor
6. Glucocorticoids
7. Parasympathomimetics

A

→ leukotriene synthesis inhibitor

54
Q

Pair the active substances to their categories!

propentophylline

The alternatives:
1. Methylxanthine derivatives
2. sympathomimetics
3. Leukotriene receptor antagonists
4. Chromones
5. Leukotriene synthesis inhibitor
6. Glucocorticoids
7. Parasympathomimetics

A

→ methylxanthine derivatives

55
Q

Pair the active substances to their categories!

nedocromil

The alternatives:
1. Methylxanthine derivatives
2. sympathomimetics
3. Leukotriene receptor antagonists
4. Chromones
5. Leukotriene synthesis inhibitor
6. Glucocorticoids
7. Parasympathomimetics

A

→ chromones

56
Q

Pair the active substances to their categories!

ipratropium

The alternatives:
1. Methylxanthine derivatives
2. sympathomimetics
3. Leukotriene receptor antagonists
4. Chromones
5. Leukotriene synthesis inhibitor
6. Glucocorticoids
7. Parasympatholytics

A

→ parasympatholytics

57
Q

Pair the active substances to their categories!

fluticasone

The alternatives:
1. Methylxanthine derivatives
2. sympathomimetics
3. Leukotriene receptor antagonists
4. Chromones
5. Leukotriene synthesis inhibitor
6. Glucocorticoids
7. Parasympathomimetics

A

→ glucocorticoids

58
Q

Pair the active substances to their categories!

terbutaline

The alternatives:
1. Methylxanthine derivatives
2. sympathomimetics
3. Leukotriene receptor antagonists
4. Chromones
5. Leukotriene synthesis inhibitor
6. Glucocorticoids
7. Parasympathomimetics

A

→ sympathomimetics

59
Q

Cross-resistance between macrolides and pleuromutilins is possible:

A. True
B. False

A

A. True

60
Q

In the case of ointments, it is not necessary to write “Externally” on the prescription, because it is never used internally:

A. True
B. False

A

B. False

61
Q

Which statement is not true for tylosin?

A. can be used in dogs to treat antibiotic responsive enteropathy

B. its tablet form does not need to be coated

C. macrolide antibiotic

D. only extra label can be used in farm animals

A

D. only extra label can be used in farm animals

62
Q

Powder for internal use can be direct administered in capsule.

A. True
B. False

A

A. True

63
Q

In the treatment of BRDC, penicillins and cefalosporins can be active against both fastidious Gram-negative bacteria and mycoplasmae.

A. True
B. False

A

B. False

64
Q

Pair each drug group with the corresponding bacteria according to potency

penicillinase-stable penicillins

A
  • Staphylococcus aureus
  • Streptococcus uberis
65
Q

Pair each drug group with the corresponding bacteria according to potency

narrow spectrum penicillins

A
  • Bacillus
  • Clostridium
  • Streptococcus
  • Erysipelothrix rhusiopathiae
  • P. multocida
66
Q

Pair each drug group with the corresponding bacteria according to potency

Anti-Pseudomonas penicillins

A
  • Streptococcus,
  • Fusobacterium
  • Bacteroides
  • E. coli
  • Pseudomonas aeruginosa
67
Q

Pair each drug group with the corresponding bacteria according to potency

broad spectrum penicillins

A
  • Bacillus
  • Clostridium,
  • Streptococcus
  • Erysipelothrix rhusiopathiae
  • E. coli
  • Salmonella
68
Q

Tetracycline antibiotics can be broken down into toxic anhydrotetracyclines

A. True
B. False

A

A. True

69
Q

Clavulanic acid is a very stable compound, so intravenous preparations containing amoxicillin clavulanic acid can be used in their aqueous solution for 3-4 days

A. True
B. False

A

B. False

70
Q

When sulfonamides are administered to domestic rabbits and poultry, vitamin K deficiency may occur, leading to bleeding

A. True
B. False

A

A. True

71
Q

Powder for external use is suitable for wound healing with talc filler.

A. True
B. False

A

B. False

72
Q

Amide type local anaesthetics are largely degraded by hepatic inactivation

A. True
B. False

A

A. True

73
Q

Codeine and butorphanol are also used for cough suppression in dogs

A. True
B. False

A

A. True

74
Q

Which of the following aminoglycoside agents has specific antiprotozoal activity?

A. tobramycin
B. amikacin
C. gentamicin
D. paromomycin

A

D. paromomycin

75
Q

How can vancomycin be administered in each indication?

A. both

B. Clostridium-associated pseudomonal colitis per os

C. none of these

D. life-threatening MRSA-associated septicaemia IV

A

A. both

76
Q

Absorption and distribution of fluconazole are excellent, it enters CNS

A. True
B. False

A

A. True

77
Q

Opioids generally cause dysphoria in dogs and euphoria in cats
A. True
B. False

A

B. False

78
Q

Clindamycin may be used in the therapy of gastrointestinal infections of pigs caused by Lawsonia intracellularis and Brachyspira hyodysenteriae

A. True
B. False

A

B. False

79
Q

Amoxicillin can be used for the treatment of mastitis in cattle via intramammary infusion, because it’s penetration through the blood- milk barrier is not enough when given parenterally

A. True
B. False

A

A. True

80
Q

Pair the agents used against ectoparasites to their description.

Animals must be served with drinking water prior to bathing with this antiparasitic agent to avoid intoxicosis

The alternatives:
1. Permethrin
2. Propoxur
3. Diazinon
4. Amitraz
5. Flumethrin
6. Couamphos

A

→ diazinon

81
Q

Pair the agents used against ectoparasites to their description.

Reversible inhibitor of acetylcholin aesterase mostly used in companion animals

The alternatives:
1. Permethrin
2. Propoxur
3. Diazinon
4. Amitraz
5. Flumethrin
6. Couamphos

A

→ propoxur

82
Q

Pair the agents used against ectoparasites to their description.

Less safe antiparasitic agent against scabies, demodicosis and ticks

The alternatives:
1. Permethrin
2. Propoxur
3. Diazinon
4. Amitraz
5. Flumethrin
6. Couamphos

A

→ amitraz

83
Q

Pair the agents used against ectoparasites to their description.

As part of the “double defense” prevention for heart worm infestation used in dogs

The alternatives:
1. Permethrin
2. Propoxur
3. Diazinon
4. Amitraz
5. Flumethrin
6. Couamphos

A

→ permethrin

84
Q

Pair the agents used against ectoparasites to their description.

Pirethroid used also in cats in antiparasitic collars

The alternatives:
1. Permethrin
2. Propoxur
3. Diazinon
4. Amitraz
5. Flumethrin
6. Couamphos

A

→ flumethrin

85
Q

Pair the agents used against ectoparasites to their description.

Organophosphate e!ective agains varroosis in honey bees

The alternatives:
1. Permethrin
2. Propoxur
3. Diazinon
4. Amitraz
5. Flumethrin
6. Couamphos

A

→ coumaphos

86
Q

Pair the substances to the appropriate description.

An antibacterial agent used both orally and parenterally in pigs, one of the main indications is enteritis caused by Escherichia coli

The alternatives:
1. Procaine penicillin
2. Collistin
3. Gentamicin
4. Tiamulin
5. Phenoxymethyl-penicillin

A

→ Gentamicin

87
Q

Pair the substances to the appropriate description.

A drug of the AMEG B category with very low absorption from the gastrointestinal tract, most commonly indicated for enteritis caused by Escherichia coli

The alternatives:
1. Procaine penicillin
2. Collistin
3. Gentamicin
4. Tiamulin
5. Phenoxymethyl-penicillin

A

→ Colistin

88
Q

Pair the substances to the appropriate description.

An antibacterial agent used orally only in pigs and poultry species, to which the bacterial species Erysipelothrix rhusiopathiae is almost always sensitive

The alternatives:
1. Procaine penicillin
2. Collistin
3. Gentamicin
4. Tiamulin
5. Phenoxymethyl-penicillin

A

→ Phenoxymethyl-penicillin

89
Q

Pair the substances to the appropriate description.

An antibacterial agent with excellent pharmacokinetic properties used for the treatment of infectious diseases of pigs and poultry species caused by mycoplasmas.

The alternatives:
1. Procaine penicillin
2. Collistin
3. Gentamicin
4. Tiamulin
5. Phenoxymethyl-penicillin

A

→ Tiamulin

90
Q

Pair the substances to the appropriate description.

Substance used parenterally in pigs only, Streptococcus suis is sensitive to this substance in almost all cases

The alternatives:
1. Procaine penicillin
2. Collistin
3. Gentamicin
4. Tiamulin
5. Phenoxymethyl-penicillin

A

→ Procaine penicillin

91
Q

Pair the active substances to their categories

ipratropium

The alternatives:
1. Enzyme reactivators
2. Parasymphatolytics
3. Parasympathomimetics

A

→ parasympatholytics

92
Q

Pair the active substances to their categories

pralidoxime

The alternatives:
1. Enzyme reactivators
2. Parasymphatolytics
3. Parasympathomimetics

A

→ enzyme reactivators

93
Q

Pair the active substances to their categories

atropine

The alternatives:
1. Enzyme reactivators
2. Parasymphatolytics
3. Parasympathomimetics

A

→ parasympatholytics

94
Q

Pair the active substances to their categories

neostigmine

The alternatives:
1. Enzyme reactivators
2. Parasymphatolytics
3. Parasympathomimetics

A

→ parasympathomimetics

95
Q

Pair the active substances to their categories

glycopyrrolate

The alternatives:
1. Enzyme reactivators
2. Parasymphatolytics
3. Parasympathomimetics

A

→ parasympatholytics

96
Q

Pair the active substances to their categories

pyridostigmine

The alternatives:
1. Enzyme reactivators
2. Parasymphatolytics
3. Parasympathomimetics

A

→ parasympathomimetics

97
Q

Pair the active substances to their categories

tropicamide

The alternatives:
1. Enzyme reactivators
2. Parasymphatolytics
3. Parasympathomimetics

A

→ parasympatholytics

98
Q

Pair the active substances to their categories

butyl-scopolamine

The alternatives:
1. Enzyme reactivators
2. Parasymphatolytics
3. Parasympathomimetics

A

→ parasympatholytics

99
Q

Pair the active substances to their categories

pilocarpine

The alternatives:
1. Enzyme reactivators
2. Parasymphatolytics
3. Parasympathomimetics

A

→ parasympathomimetics

100
Q

Pair the active substances to their categories

betanechol

The alternatives:
1. Enzyme reactivators
2. Parasymphatolytics
3. Parasympathomimetics

A

→ parasympathomimetics

PHARMA EXAM (6 decks)

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