5.4 Hormonal Communication Flashcards
What is an endocrine gland?
A ductless gland that secretes it’s product directly into the blood or lymph
What is an exocrine gland?
A gland that secretes it’s product into a duct which takes the secretions to the site of action
What are the 2 types of hormone?
- steroid
- protein
What are the features of protein hormones?
- insoluble so can’t diffuse through plasma membrane
- requires receptors
what are the features of steroid hormones?
- soluble so can pass through plasma membrane
- bind to receptors on cytoplasm
what are examples of steroid hormones?
- testosterone
- progesterone
what are examples of protein hormones?
- insulin
where are the adrenal glands found?
above the kidneys
what are the 2 parts of the adrenal gland?
- adrenal cortex
- adrenal medulla
what does the adrenal cortex produce?
steroid hormones using cholesterol:
- glucocorticoids
- mineralocorticoids
what is an example of a glucocorticoid?
- cortisol
It stimulates the synthesis of glycogen in the liver and is released in response to stress
what is an example of a mineralocorticoid?
- aldosterone
It is release to increase the uptake of Na+ and K+ into the blood from the DCT
what does the adrenal medulla produce?
- protein hormones
e.g. adrenaline
how do protein hormones work?
- protein bins to receptor on plasma membrane, which activates a G protein.
- G protein activates an effector molecule which produces an enzyme to convert ATP to cAMP
- cAMP is the secondary messenger which activates an enzyme cascade or acts directly on other proteins
how do steroid hormones work?
- steroid hormone passes through plasma membrane and binds to receptor in cytoplasm or nucleus
- the receptor steroid hormone complex acts as a transcription factor resulting in the formation of mRNA by transcription
- a new protein is formed