5.4 Flashcards
What is a mutation
change in the base sequence order in a DNA molecule
If the structure of DNA changes enough
will cause RNA to change which will lead to a change in proteins
What is a wild type?
to most common type of sequence in a population
What are the 2 main types of mutations?
Point mutations and frameshift muations
What happens in a point mutation
substitution of a single base
What are the types of point mutations
Silent mutation, missense, and nonsense
What is a silent mutation?
no amino acid is changed
theres a redundancy in the code
What is a missense mutation
change amino acid
What is a nonense mutation
change to a stop codon
Which type of point mutation(s) cause the most change
missense and nonsense
WHat happens in a frameshift mutation
shifts the reading frame, everything changesdown stream
kinds of frame shift muations
insertions and deletions
WHat happens in frameshift deletions
losing base(s)
What happens in frame shift insertions
adding base(s)
When does mutation occur
during DNA replication
