5.2 Reproductive health

Question 1

why is progesterone dominant in 2nd half of menstrual cycle?

Answer 1

stop over proliferation of endometrium

Question 2

how many COCPs need to be taken to be effective?

Answer 2

7

Question 3

why does POP increase risk of ectopic?

Answer 3

ovulation occurs, but ovum not moved along Fallopian tube due to reduced cilia activity, so is sperm reaches, can implant in tube

Question 4

intermediate symptoms of menopause

Answer 4

vaginal atrophy
dyspareuina
skin atrophy
urge/stress incontinence

Question 5

late symptoms of menopause

Answer 5

osteoporosis
atherscleoris
alzheimers

Question 6

HRT for vasomotor/mood symptoms
-with uterus
-wihtout

Answer 6

-combined
-oestrogen only

Question 7

how do bisphosphonates treat osteoporosis?

Answer 7

reduce bone turnover by controlling osteoclast activity

Question 8

how to take bisphosphonates and why?

Answer 8

empty stomach, once weekly large dose as tricky to take

affected by food, poor gut absorption

Question 9

ADRs from bisphosphonates, and how to minimise

Answer 9

oesophagitis: sit/stand for 30 mins after

hypocalcaemia: check vit D/ calcium before treatment