3.1 HTN

Question 1

target BP for different groups

Answer 1

<80 and type 2 diabetes: <140/90

> 80: <150/90

type 1: <135/85

Question 2

why can ACEi and ARBs cause hyperkalaemia?

Answer 2

lower aldosterone so less K+ excreted

Question 3

contraindications for ACEi and ARBs

Answer 3

-AKD
-pregnancy
-angioedema
-renal artery stenosis

Question 4

drug interactions for ACEi and ARBs

Answer 4

-NSAIDs
-antihypertensives

Question 5

why might CCBs be used for low renin patients?

Answer 5

targeting RAAS is less effective without renin

Question 6

contraindications for dihydropyridines

Answer 6

unstable angina
severe aortic stenosis

Question 7

drug interactions for dihydropyridines

Answer 7

amlodipine
simvstatin

Question 8

contraindications for phenylalkylamines

Answer 8

poor LV func
AV node conduction delay

Question 9

drug interactions for phenylalkylamines

Answer 9

-B blockers
-other antiHTN

Question 10

what should be considered in resistant hypertension, before adding more drugs?

Answer 10

ensure no secondary cause, and BP is being measured accurately, and patient is actually taking current drugs

Question 11

how to decide beta blocker selectivity

Answer 11

A-N B1 selective
O-Z B2 selective

not ‘olol’= A and B receptor activation

Question 12

contraindications for B blockers

Answer 12

asthma, liver failure

Question 13

drug interactions for B blockers

Answer 13

non-dihydropyridine CCBs (Asystole)

Question 14

management of QRISK <10%

Answer 14

lifestyle modifications
review comorbidiites
risk assess in 5 years

Question 15

management of QRISK >10%

Answer 15

check for familial lipid disorder, or secondary causes

lifestyle modification, comorbidities review (support?)

atorvastatin 20mg daily