52: Randomised Controlled Trials Flashcards
1
Q
What are the indications for a RCT?
A
- Gold standard for treatment/intervention effectiveness
- Reduces confounding
2
Q
What are the problems with RCTs?
A
- Compliance
- Cost
- Non-representative populations (small populations)
3
Q
What is the purpose of stratified randomisation?
A
- Dividing into high and low risk patients
- To ensure there are similar proportions of high and low risk patients in each population
4
Q
Why do RCTs have a large random error?
A
Small amount of events - large confidence intervals
