5.1.1 Communication and Homeostasis Flashcards
What set of conditions do living things need to maintain in their cells?
- a suitable temperature
- a suitable pH
- an aqueous environment that keeps substrates and products in solution
- freedom from toxins and excess inhibitors
What are the threats from different changing environments?
Changing external environments:
- external environment changes may place stress on living organism
- environmental change is stimulus and way organism changes is its response
Changing internal environments:
- as cells undergo various metabolic acitivities, they use up substrates and create new products, which may be unwanted or toxic e.g. CO2
- therefore, the activities of the cells alter their own environment
Maintaining internal environment:
- blood flows throughout body and transports substances to and froom cells
- concentrations of waste products are monitored closely to ensure body does not excrete too much useful substance, but also removes waste products to maintain good health
Coordinating activities of different organs
- cover whole body
- enable cells to communicate with each other
- enable specific and rapid communication
- enable both short and long term responses
What is cell signalling?
- the process by which cells communicate with each other
What are the two major systems of communication that work by cell signalling?
Neuronal system:
- an interconnected network of neurones that signal to each other across synpase junctioins
- neurones can conduct a signal very quickly and enable rapid responses to stimuli that may be changing quickly
Hormonal system:
- a system that uses the blood to transport its signals
- cells in an endocrine organ release the signal ( a hormone) directly into the blood
- the hormone is transported throughout the body, but only recognised by specific target cells
- this system enables longer-term responses to be coordinated
Definition of homeostasis
- maintaining a constant internal environment despite changes in external and internal factors
Give examples of aspects that homeostasis may maintain
- body temperature
- blood glucose concentration
- blood salt concentration
- water potential of blood
- blood pressure
- CO2 concentration
What is the standard response pathway for the mechanism of homeostasis?
stimulus → receptor → communication pathway (cell signalling) → effector → response
What type of specialised structures are required for the standard response pathway to work?
- sensory receptors: e.g. temperature receptors
- these may be on the surface of the body which monitors changes in the external environment
- they may also be receptors that measure conditions internally
- when they detect a change, it will be stimulated to send a message to an effector
- a communication system such as a neuronal system or hormonal system
- this acts by signalling between cells
- transmits a message from receptors cells to the effector cells via a coordination centre
- effector cells: bring about a response
What is negative feedback and how does it work?
- the mechanism that reverses a change, bringing the system back to the optimum
- when conditions change, receptors detect this stimulus and send an input to the coordination centre
- coordination centre sends an output to the effectors and effectors responds to it
- the change moves the system closer to optimum and stimulus is reduced
- so, the receptors detect the reduction in stimulus and reduce input to coordination centre
- output from coordination centre to effectors also reduced, so less effector activity
Give an example of a negative feedback loop using temperature
Why can conditions never remain perfectly constant?
- there will be some variation around the optimum condition
- response may slightly ‘overshoot’ but remain acceptable
What is positive feedback and how does it work?
- the mechanism that increases a change, taking the system further away from the optimum
- tend to be harmful as it destabilises the system
Give a positive and negative example of positive feedback
Negative:
- e.g. below certain core body temperature enzymes become less active and the exergonic reactions that release heat are slower and release less heat
- this allows body to cool further, slowing enzyme-controlled reactions even more, so body temperature spirals downwards
Positive:
- at end of pregnancy, as the cervix begins to stretch, the posterior pituitary gland secretes the hormone oxytocin
- oxytocin increases the uterine contractions which stretches cervix more, which causes secretion of more oxytocin
- this allows cervix to be fully dilated
Why is controlling body temperature important?
- effect upon the activity of cell processes: hen temperature rises, molecules have more kinetic energy, so more frequent collisions mean chemical reactions occur more quickly and vice versa
- may affect structures of proteins
- some enzymes are very sensitive to temperature change
- core temperature is important as all vital organs are found in the centre of body
What is an ectotherm?
- an organism that relies on external sources of heat to maintain body temperature
- not able to control their body temperature as effectively as endotherms