5- Pathophysiology of traumatic brain injury Flashcards
T/F Dogs & cats have a remarkable ability to compensate for loss of cerebral tissue
True
T/F perfusion decreases if the brain enlarges
True
How is secondary brain injury triggered
Is triggered by Excitatory neurotransmitters
By ROS (reactive oxygen species)
And Pro-inflammatory cytokines
Name 2 systemic contributions to secondary brain injury
Hypotension
hypoxia
hypo/hyperglycaemia
hypo/hypercapnia
hyperthermia
What makes up the initaial neurologic assessment
consciousness
breathing pattern
pupil size and responsiveness
ocular position and movements
skeletal motor responses
What is MGCS
modified glasgow coma scale- evaluates the neurological function
higher scores correlates with a better prognosis
Level of consciousness most reliable measure o impaired cerebral function
What does secondary brain injury lead to
cerebral oedema formation
increased intracranial pressure
compromised to the blood-brain barrier
alterations in cerebrovascular reactivity