[5] Common Infections in Obstetrics

Question 1

What test indication would indicate an Acute Infection of Hepatitis B

Answer 1

IgM Anti-HBc

Question 2

Why do we test for Anti-HAV IgM for diagnosing HBV

Answer 2

To exclude acute viral Hepatitis A on top of Chronic Hepatitis B

Question 3

Optimal period of time to give active and passive vaccine to neonates

Answer 3

Within 12 hours

Question 4

Do all pregnant women have to be screened for ASB?

Answer 4

Yes, and a URINE CULTURE has to be done, not a urinalysis

Question 5

Most common urinary tract complication in pregnant women

Answer 5

Acute Pyelonephritis

Question 6

Most common pathogen of Acute Pyelonephritis

Answer 6

E. Coli

Question 7

Why can you not give Nitrofurantoin during 3rd Term Pregnancy/After 34th week

Answer 7

Affects glutathione reductase activity leading to hemolytic anemia in babies with G6PD deficiency

Question 8

Why do you not give Co-amoxiclav during the 1st and 3rd Trimester?

Answer 8

Necrotizing Enterocolitis without prolonging pregnancy

Question 9

Why do you not give Cotrimoxazole 1st and 3rd Trimester?

Answer 9

Sulfonamides may cross the placenta and are excreted in the milk causing kernicterus

During pregnancy they may interfere with folic acid metabolism

Question 10

Most common cause of Pneumonia in children

Answer 10

Haemophilus influenzae

Question 11

Good quality Sputum CS

Answer 11

25 LPF

Question 12

Most common STI causing Vaginitis

Answer 12

Triochomonas vaginalis

Question 13

Trichomonas is what kind of an organism?

Answer 13

Protozoan

Question 14

How do you give Metronidazole during pregnancy with TV?

Answer 14

2 grams single dose

Question 15

How do you give Clindamycin during pregnancy with TV?

Answer 15

300 mg 2x/day for 7 days

Question 16

Function of Benzathine in relation to Penicillin

Answer 16

Extends its half life

Question 17

[Interpret]

HBsAG ( - )
Total Anti-HBc ( - )
Anti-HBs ( - )

Answer 17

Susceptible

Question 18

[Interpret]

HBsAG ( + )
Total Anti-HBc ( + )
IgM Anti-HBc ( + )
Anti-HBs ( - )

Answer 18

Acute Infection

Question 19

Treatment for HB Positive Pregnant Mothers

Answer 19

Tenofovir > Telbivudine > Lamivudine

Question 20

How do you characterize high quality of evidence, strong recommendation for Asymptomatic Bacteriuria

Answer 20

2 consecutive voided or one catheterized urine specimen with bacterial strain greater than 100,000 CFU/mL

Question 21

Antibiotics for ASB in Pregnancy

Answer 21

Nitrofurantoin
Co-Amoxiclav
Cephalexin
Fosfomycin
Cotrimoxazole

Question 22

Duration of treatment for acute uncomplicated pyelonephritis

Answer 22

14 days

Question 23

Pleural effusion is present in 50% of pneumonia cases caused by this organism

Answer 23

H. influenza

Question 24

Management of Low Risk CAP

Answer 24

Previously Healthy: Amoxicillin

Stable Comorbid Disease: B-Lactam Inhibitor / 2nd Gen Cephalosphorin

Question 25

Management of Moderate Risk CAP

Answer 25

IV Nonpseudomonal B-Lactam + Extended macrolides

Question 26

Management of High Risk CAP

Answer 26

IV Antipneumococcal Antipseudomonal B-Lactam + Macrolide + Aminoglycoside

Question 27

Leading cause of neonatal morbidity and mortality

Answer 27

Preterm Birth

Question 28

Most common pathway of Intrauterine Infection

Answer 28

Ascending route from vagina and cervix

Question 29

Should you administer Metronidazole or Clindamycin for pregnant patients with BV

Answer 29

Clindamycin

Metronidazole causes increased risk of preterm births and low birth weight

Question 30

Most common form of Group B Streptococcus disease

Answer 30

Bacteremia (80%)

Question 31

Drug of choice for GBS

Answer 31

Penicillin

Question 32

Diagnostic Test of Choice for Chlamydia

Answer 32

Nucleic Acid Amplification Tests (NAATs: 99-100% specificity)

Question 33

Treatment for Pregnant Women with Chlamydia

Answer 33

Azithromycin 1g PO SD

Amoxicillin 500 mg PO TID x 7 days

Question 34

Diagnostic Method for Gonococcal Infections

Answer 34

Nucleic Acid Amplification Tests

PCRs are highly sensitive and specific

Question 35

First Line Treatment for Gonococcal Infections

Answer 35

Ceftriaxone 250mg IM SD

Question 36

Treatment for Congenital Syphillis

Answer 36

Benzathine Penicillin

Question 37

Recommended Diagnostic Test for Toxoplasmosis

Answer 37

PCR from Amniotic Fluid

Question 38

Treatment for Toxoplasmosis

Answer 38

Spiramycin

Question 39

Kissing Disease is caused by

Answer 39

Cytomegalovirus

Question 40

Most common method of neonatal Herpes Infection

Answer 40

Peripartum

Question 41

Treatment for Herpes Infection

Answer 41

Acyclovir