[2] Abnormalities of Development of the Reproductive Tract Flashcards
Migration of Germ Cells is from?
Yolk Sac to the Genital Ridge
DHT Deficient Males presentation at birth
Undescended testes at birth
No prostate
Partially formed vagina
Ambiguous at birth
Most common germ cell tumor resulting from failure of proper migration of germ cells from yolk sac to genital ridge
Sacrococcygeal Teratoma
Hormones produced by Leydig Cells
Testosterone
5-DHT
Hormones produced by Sertoli Cells
Anti-Mullerian Hormone
Patient with Androgen Insufficiency Syndrome will present as a male or female?
Female
Testes and Ovaries are derived from (3)
- Mesodermal epithelium
- Underlying mesenchyme
- Primordial Germ Cells
Only body part with receptors for SRY Antigen
Genital Ridge
Responsible for Testis Differentiation
SRY Antigens on the Genital Ridge
What differentiates into seminiferous tubules?
Medullary Cords of the Primitive Gonad
Origin of Leydig Cells
Interstitial Cells
Enzyme that converts Testosterone to 5-DHT
5-Alpha Reductase
Testosterone stimulates the Wolffian Duct to form?
Vas Deferens
Seminal Vesicles
Epididymis
Primitive gonads normally differentiate into?
Ovaries
[Fate in Males and Females]
Genital Tubercle
M: Glans Penis
F: Clitoris
[Fate in Males and Females]
Genital Folds
M: Penile Urethra
F: Labia Minora
[Fate in Males and Females]
Genital Swellings
M: Scrotal Sacs
F: Labia Majora
[Fate in Males and Females]
Urogenital Sinus
M: ?
F: Lower Vagina
Mullerian Ducts form?
Fallopian Tube
Uterus
Cervix
Upper Vagina
2 Phases of Testes Descent
- Transabdominal Descent
2. Inguino-scrotal Migration
How many months AOG for complete descent of testes?
7 Months
Transabdominal Phase is controlled by?
Anti-Mullerian Hormone
Inguino-scrotal Migration is dependent by?
Androgen-dependent via Genitofemoral Nerve
In Cryptorchidism this testis is usually undescended
Right Testis
