[46] Role of Epigenetics in Thermogenesis Flashcards
What is the role of epigenetics in thermogenesis?
Epigenetics can regulate gene expressions that are critical for thermogenic function, affecting metabolic rate, body weight regulation, and adaptation to environmental temperatures.
How does epigenetic modification influence thermogenesis?
Epigenetic modifications can change the expression of genes involved in thermogenesis without altering the underlying DNA sequence. This can result in changes in energy metabolism and heat production.
What is the connection between epigenetics and brown adipose tissue (BAT) in thermogenesis?
Epigenetic modifications can influence the amount, distribution, and activity of BAT, which plays a key role in non-shivering thermogenesis.
What is the role of DNA methylation in thermogenesis?
DNA methylation, an epigenetic mechanism, can alter the expression of genes involved in thermogenesis and influence metabolic processes such as energy expenditure and heat production.
How do histone modifications affect thermogenesis?
Histone modifications, which are epigenetic changes, can alter the structure of chromatin and subsequently influence gene expression related to thermogenesis.
What is the role of non-coding RNAs in thermogenesis and how are they influenced by epigenetics?
Non-coding RNAs, regulated by epigenetic mechanisms, can affect thermogenesis by influencing the expression of genes involved in energy metabolism and heat production.
What is BAT?
BAT stands for brown adipose tissue, a type of body fat involved in burning energy and producing heat, hence playing a significant role in thermogenesis.