[46] Role of Epigenetics in Thermogenesis Flashcards

1
Q

What is the role of epigenetics in thermogenesis?

A

Epigenetics can regulate gene expressions that are critical for thermogenic function, affecting metabolic rate, body weight regulation, and adaptation to environmental temperatures.

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2
Q

How does epigenetic modification influence thermogenesis?

A

Epigenetic modifications can change the expression of genes involved in thermogenesis without altering the underlying DNA sequence. This can result in changes in energy metabolism and heat production.

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3
Q

What is the connection between epigenetics and brown adipose tissue (BAT) in thermogenesis?

A

Epigenetic modifications can influence the amount, distribution, and activity of BAT, which plays a key role in non-shivering thermogenesis.

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4
Q

What is the role of DNA methylation in thermogenesis?

A

DNA methylation, an epigenetic mechanism, can alter the expression of genes involved in thermogenesis and influence metabolic processes such as energy expenditure and heat production.

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5
Q

How do histone modifications affect thermogenesis?

A

Histone modifications, which are epigenetic changes, can alter the structure of chromatin and subsequently influence gene expression related to thermogenesis.

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6
Q

What is the role of non-coding RNAs in thermogenesis and how are they influenced by epigenetics?

A

Non-coding RNAs, regulated by epigenetic mechanisms, can affect thermogenesis by influencing the expression of genes involved in energy metabolism and heat production.

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7
Q

What is BAT?

A

BAT stands for brown adipose tissue, a type of body fat involved in burning energy and producing heat, hence playing a significant role in thermogenesis.

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