4.3: Renal, Testicular and Penile Cancer Flashcards

1
Q

Describe the different types of renal tumour?

A

Benign

Renal Pelvis Tumours

Renal Parynchema Tumours

Embryonic Tumours

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2
Q

Describe imaging of renal tumours?

A

Ultrasound

CT

MRI

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3
Q

How are the majority of renal tumours discovered?

A

Incidental Findings

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4
Q

Describe benign renal cysts?

Diagnosis?

How are they often found?

A

70% of benign asymptomatic renal lesions

Fluid filled lesion

They can be single or multiple cysts

Very common (1/10 people)

Ultrasound is the best way

Contrast CT

Often incidental finding

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5
Q

Describe Angiomyolipoma?

Diagnosis?

Risks/Side effects?

A

Benign

Composed of muscle, blood vessels and fat

Diagnosed using CT

Can haemorrhage and requires embolization

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6
Q

Describe Oncocytoma?

Diagnosis?

Treatment?

A

Benign - doesn’t metastases

Make up about 3-7% of renal tumours

CT shows central scar

Often there is nephrectomy due to size and also concern that is may be cancerous (very hard to differentiate)

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7
Q

Describe the classic presentation of a renal cell carcinoma?

How is this often found?

A

Loin Pain

Renal Mass

Haematuria

Often incidental finding

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8
Q

Renal Cell Carcinoma:

Men/Women?

Age?

A

More common in males

Peak age range about 65-75

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9
Q

Describe the types of renal cell carcinoma?

A

Adenocarcinoma of proximal convoluted tubule

Can be clear cell (most common) or papillary

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10
Q

Diagnosis of renal cell carcinoma?

A

Ultrasound

CT

Biopsy (High False Negative)

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11
Q

Describe the staging of Renal Cell Carcinoma?

Where does this metastases to?

A

Robson Staging

Bone, Brain, Lungs, Liver

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12
Q

Treatment of renal cell carcinoma?

A

Radical Nephrectomy

Partial Nephrectomy

Radiofrequency Ablation

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13
Q

Describe BXO?

A

Balanitis Xerotica Obliterans

Pre-malignant cutaneous lesions

There is white patches, fissuring, scaring, bleeding

Main cause tight foreskin in older men

Treated with circumcision

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14
Q

Describe squamous cell carcinoma in situ?

A

Erthyroplasia of Queyrat - if on the glans, prepuce or shaft

Bowen’s Disease - anywhere else on penis

Presents as red velvety patches

Needs differentiated from benign causes

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15
Q

What does this photo show?

A

BXO

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16
Q

What does this photo show?

A

Squamous Carcinoma in Situ (bowen’s disease of erythroplasia of Queyrat)

17
Q

Describe presentation of squamous carcinoma of penis?

A

Often late presentation

Red raised area of penis

Foul smelling

Phimosis (Unable to retract foreskin)

18
Q

Diagnosis of squamous cell carcinoma of the penis?

A

Biopsy

Ultrasound

MRI

19
Q

Peak age incidence of squamous cell carcinoma of penis?

Common?

Role of HPV?

Role of circumcision?

A

80

Not that common

HPV 16 indicated

Circumcision is protective

20
Q

Treatment of carcinoma of the penis?

A

Surgery for primary tumour

Radiotherapy

21
Q

Describe the germ cell tumours of the testis?

How common are these?

A

Seminoma

Teratoma

ITGCN (Intra-tubular germ cell neoplasia)

Not that common

22
Q

Describe presentation of testicular tumours?

Diagnosis?

A

Painless swelling of testis

Non tender

Diagnosis based on ultrasound and markers

23
Q

Describe the markers in testicular tumours?

A

AFP - Alpha Feta Protein

HCG (Beta-HCG)

LDH

24
Q

True or False:

AFP is always raised in pure seminoma

A

False

AFP is never raised in pure seminoma

25
Q

Raised HCG suggests… (Which tumour)?

A

Teratoma

26
Q

Describe the role of the markers POST surgery?

A

Can be used to see if the surgery has been sucessful

27
Q

Treatment of testicular tumours?

A

Surgery (Orchidectomy)

Chemotherapy

Radiotherapy

28
Q

Management of carcinoma in situ?

A

Radiotherapy

29
Q

Management of Seminoma?

A

Radiotherapy

Chemotherapy

30
Q

Management of Teratoma?

A

Surveillance

Chemotherapy