4.2 Nursing Management of Chronic Kidney Disease Flashcards
Chronic Kidney Disease (CKD)
- Umbrella term for kidney damage or decrease in GFR lasting 3 months or more
- More progressive than Acute Kidney Failure/Injury
- Untreated CKD can result in renal replacement, dialysis, or kidney transplant
CKD Risk Factors
- CVD
- Diabetes (Leading Cause)
- Hypertension (Second Leading Cause)
- Obesity
CKD Stages and GFR
- Based on GFR (plasma filtered through glomeruli per unit of time)
- Normal GFR 125 mL/min.
Nephrosclerosis
- Hardening of renal arteries due to prolonged hypertension and DM
Primary Glomerular Disease
(Group A Beta-Hemolytic Strep Infection)
- Destroys glomerulus of kidneys
- 3rd most common cause of stage 5 CKD
Acute Nephritic Syndrome - Glomerular Inflammation
(Post-Infectious Problem)
Chronic Glomerulonephritis - Repeated syndromes of Acute Nephritic Syndrome
Nephrotic Syndrome - Any condition that damages glomerular membrane and results in increased glomerular permeability to plasma proteins
Polycystic Kidney Disease
- Genetic
- Characterized by growth of numerous fluid filled cysts in kidneys which destroy nephrons.
- Can lead to chronic kidney failure and nephrosclerosis.
End Stage Kidney Disease (ESRD)
- GFR < 15
Acute Kidney Injury (AKI)
- Rapid loss of renal function due to damage to kidneys
- Treatment is to replace renal function temporarily to minimize lethal complications
- Goal of minimizing long-term renal function loss
- Results in drop of glomerular filtration rate, increased creatinine, dropping urine output.
- Reversible
Pre-Renal
- Hypoperfusion of kidneys (volume depletion, decreased cardiac output; shock)
- Replace fluids and vasopressors
- Can see Hypertension or Hypovolemia
Intra-renal
Actual damage to kidney tissues.
Nephrotoxic agents like antibiotics (gentamicin vancomycin) can cause damage to kidneys
Acute Tubular Necrosis (ATN)
- Damage to kidney tubules; most common type of intrinsic AKI
Post-Renal
- Obstruction to renal flow
Tumor, prostate, hyperplasia, stones
RIFLE (Stages of Kidney Disease)
R - Risk of first stage AKI (First Stage) I - Injury (Second Stage) F - Failure (Third/End Stage) L - Loss E - End Stage Renal Failure
Continuous Renal Replacement Therapy (CRRT)
- Common renal support for AKI
- Particularly for patients who are hemodynamically stable
- Continuous venovenous hemofiltration with either convective solute clearance, diffuse solute clearance, or hemodiafiltration (combines both dialysis and hemofiltration)
Continuous Venovenous Hemofiltration (CVVH)
- Temporary treatment for patients with acute renal failure who are unable to tolerate hemodialysis.
- Dialysis catheter placed in main vein of body. Blood is taken out of body, goes into a filter, wastes are removed and fluids/electrolytes are replaced, then returned to body.