402 Pain Flashcards
Drug classification of
CELECOXIB
Nsaid
Drug classification of
PENTAZOCINE
Opioid agonist-antagonist analgesic
Drug classification of
PREDNISONE
Glucocorticoid
Drug classification of
ASPIRIN
NSAID
Drug classification of
BUTORPHANOL
Opioid agonist-antagonist analgesic
Drug classification of
TRAMADOL
Centrally acting analgesic
Drug classification of Acetaminophen
Nonopioid analgesic
Drug classification of Morphine
Opioid agonist analgesic
Drug classification of Ibuprofen
Nsaid
Drug classification of. NALOXONE
Opioid antagonist
Where are most nsaid metabolized?
By the liver
And excreted—— by the kidneys
All nsaids have antipyretic and analgesic properties.
T/f
T
Black box warning for ibuprofen and other nsaids?
Increased risk of thromboembolic events (including stroke and MI) and can worsen HTN
What does the prolonged antiplatelet action that aspirin have increase risk of?
Potential bleeding
A patient is taking acetaminophen. What adverse effect should be monitored?
Lethargy.
What adverse effects of NSAIDs should be watched for?
Dyspepsia
Tinnitus
Blood dyscrasias
What is the primary cause of severe inflammation
Lymphocytes and macrophages
Does acetaminophen decrease inflammation?
No
What laboratory test would show inflammation
C-reactive protein
Mechanism of action of NSAIDs in treating inflammation
They inhibit the synthesis of prostaglandins
What are prostaglandins
Hormones found in every tissue
What chemical mediator is a vasodilator and can cause pain
Bradykinin