402-immune Flashcards

1
Q

TheraCys (BCG vaccine) is prescribed to a patient for bladder cancer. How is it administered

A

Intravesical. Directly into the bladder.

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2
Q

Aldesleukin (Proleukin) is administered how and for what

A

Intravenously for…

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3
Q

What do interferons (IFNs) do to help fight infection?

A

They alert healthy cells to a virus ands then attach to nearby unaffected cells, inducing the production of protective antiviral proteins.

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4
Q

A patient is beginning immunotherapy. Which adverse effects should the nurse instruct the patient to report to their provider?

A

Lethargy, mood or behavior changes, confusion, and disorientation.

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5
Q

When is RhoGAM needed

A

If the mother is Rh- and the fetus is Rh+

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6
Q

A patient recently received a kidney transplant. Which vaccination should the nurse question before giving to this patient?
A) MMR
B) Tetanus toxoid
C) influenza
D) Hep B.

A

MMR. Cause it’s live

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7
Q

What is cyclosporine (Neoral) used for

A

Immunosuppressant

It is a calcination inhibitor used as prophylactic treatment in various organ transplants. And can be used for severe cases of crohns or ulcerative colitis

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8
Q

A patient has a yeast allergy. What vaccine should be questioned prior to administration?
A) influenza
B) tetanus toxoid
C)hep B
D) RhoGAM

A

Hep B. It is produced through recombinant DNA using yeast cells.

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9
Q

What drug is capillary leak syndrome an adverse effect of

A

Aldesleukin (Proleukin)

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10
Q

Older patients receiving immunostimulants need what precautions

A

Fall risk precautions

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11
Q

Why would someone be prescribed the HBIG vaccine
(Hepatitis B immune globulin)

A

If they were exposed to hepatitis B infected blood.

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12
Q

Common adverse effects of interferon Alfa-2b (Intron-A)

A

Nausea, vomiting, diarrhea

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13
Q

Why is penicillin G preferred for the treatment of streptococcal bacterial endocarditis

A

It has a narrow spectrum of anti microbial activity and is widely distributed throughout the body. It is most effective against gram-positive organisms.

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14
Q

Tetracyclines are broad spectrum or narrow spectrum and what kind of organisms does it treat

A

Broad spectrum. Both gram positive and negative.

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15
Q

Aminoglycosides are only effective in the treatment of what kind of organisms

A

Gram negative

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16
Q

Macrolides treat gram positive or gram negative?

A

Gram positive

17
Q

What is the most common site of HAI (healthcare associated infection)

A

Urinary tract

18
Q

Which class of antibiotics exert the broadest spectrum of bactericidal activity of any of the antibiotics

A

Carbapenems

19
Q

A patient being treated for a urinary tract infection develops severe diarrhea and fever. What health problem should the nurse suspect

A

Superinfection

20
Q

Trimethoprim-sulfamethoxazole contraindications

A

Patients with folate deficiency anemia
Sulfa allergies
Severe renal or hepatic impairment

21
Q

Which medication would be anticipated for a patient with severe C.diff

A

Vancomycin

22
Q

Probenecid (probalan) has what interaction with acyclovir

A

It decreases elimination of acyclovir and can lead to toxic levels.

23
Q

A virus does not have the capacity for self survival.
T/f

A

T

24
Q

Efavirenz (sustiva) should be taken with food.
T/f

A

False it should be taken in an empty stomach.

25
Q

Maraviroc (selzentry) mechanism of action

A

Block the CCR5 coreceptor which reduces the viral load and increases t-cell production.

26
Q

Which antiviral drugs block the synthesis of viral DNa

A

Reverse transcriptase inhibitors.

27
Q

A patient treated for HIV with Zidovudine (AZT, Retrovir) would be screened for what prior to starting this med?

A

Anemia as this drug suppresses bone marrow function