4. Fuel for life Flashcards

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1
Q

Digestion

A

= the mechanical and chemical breakdown of food to absorb nutrients and functioning

  • essential for energy, growth and maintenance of our bodies
  • glucose is an essential source of energy release from varied food sources by enzymes and hormone insulin
  • in healthy body water, monosaccharides, aa, fatty acids and glycerol, vitamins and minerals absorbed within an appropriate range
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2
Q

Digestive system anatomy in order

A
  • Oral cavity
  • salivary glands
  • saliva
  • oesophagus/ esophagus
  • stomach
  • small intestine
  • Accessory organ secretion - liver and pancreas
  • large intestine
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3
Q

Oral cavity

A

= lips cheeks, teeth and tounge

mechanical - biting and chewing mechanics chops food into small pieces to swallow

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4
Q

Salivary glands

A

= 3 pairs - parotid, submandibular and sublingutar glands

  • produce saliva through ducts into mouth
  • Salivary amylase enzymes converts polysaccharides to disaccharides
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5
Q

Saliva

A

= mixture of serous and mucus fluids

serous (watery) component 
   - moistens food for swallowing 
   - dissolves food for tasting 
   - contains enzymes amylase - carbohydrates for state of 
     chemical digestion 

mucous component

  • lubricates food
  • enzyme lysosym is antibacterial
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6
Q

Oesophagus

A

= muscular contractions in oesophagus occur in peristaltic waves to push food down tract

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7
Q

Stomach

A

= huge muscular sac that is a J shaped enlargement of GI tract (4 functions) - food churned (mechanical breakdown)

  1. Mixes saliva, food, gastric juice to form chyme (chemical breakdown)
  2. Serves as a resviour for food before release into small intestine
  3. Secretes gastric juice, which contains
    - HCL - kills bacteria dn denatures proteins
    - pepsin - begins the digestion of proteins
    - intrinsic factor - aids absorption of vitamin B12
    - gastric lipase - aids digestion of triglycerides
  4. secretes gastrin into blood
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8
Q

Small intestine

A

= digestion and absorption

  • three parts - Duodenum, jejunum and ileum

Modification increase surface area

  • circular folds: mucosa and submucosa
  • Cilli: finger like projection from mucosa
  • microvilli
  • food entering the small intestine is only particularly digested
  • secrets digestive enzymes
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9
Q

Accessory organ secretion

A

Liver = produces bile to aid digestion

  • stored in galbladder
  • bile allows secretion

Pancreas

  • bicarbonate to neutralise acidic chyme
  • enzymes
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10
Q

Large intestine

A

4 main functions

  • reabsorption of water and mineral ions
  • formation and temporary storage of faeces
  • maintain residence pop of over 500 species of bacteria
    - assist vitamin production
    - defecation (empty rectum)

Colon = mucosal lining with tubular glands which contains mucous producing goblet cells

Rectum = straight muscular tube

Anal canal = waste on the way out

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11
Q

Anatomy of the GI tract

A

4 layers of tissue called tunics:

  1. Tunica Serosa - protection/ covering
  2. Tunic muscularis - longitudinal and circular which work together to propel food/ chyme through digestive tract
  3. Tunic submucosa - loose tissue containing blood and lymphatic vessels, provide nervous control to mucosa
  4. Tunica mucosa - inner layer - secretion, absorption and hormone
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12
Q

What does the stomach absorb

A

=water , alcohol, aspirin

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13
Q

Pancreas

A
  • gland that lies in the posterior of the stomach
  • produces enzymes that digest carbohydrates, proteins, fats, nucleic acids
  • produces bicarbonate
  • empties contents into duodenum
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14
Q

Endocrine and exocrine function in pancreas?

A

Endocrine = organs release hormones
- insulin and glucagon

Exocrine = relate to releasing a substance through a duct

  • release enzymes that aid digestion
  • pancreatic lipase
  • amylase
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15
Q

Pancreatic juice

A

= helps to protect and prevent erosion of the intestinal mucosa

  • digestive enzymes which breakdown
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16
Q

Bile

A

= bile acids are critical for digestion and absorption of fats in small intestine

  • contains waste products which are eliminated from the body via secretion into bile e.g. bilirubin
  • stored in gallbladder
17
Q

What is cirrhosis

A
  • liver damage from alcohol abuse leading to many issues with liver
  • no storage site for carbohydrates
18
Q

Metabolism

A

= refers to all chemical processes occurring within a cell or organism that are necessary for the maintenance of life

  • nutrients are broken down in GI tract, absorbed into the blood an then transported to the cells
  • in the cells these molecules are either catabolised or anabolism
19
Q

What is Catabolism

A

= the process by which metabolic pathways break down molecules into smaller units and release energy

Large molecules are broken down into digestible units

  • polysaccharides - monosaccharides
  • lipids - fatty acids
  • proteins - aa
20
Q

What is Anabolism

A

= set of metabolic pathways that construct molecules from smaller units

e.g. production of protein from aa

21
Q

The kidney

A

= remover of wastes, maintainers of balance

  • maintain extracellular fluid composition and volume
  • filtration and reabsorption
  • secretion of some waste products
  • produce some hormones
  • contains nephrons
22
Q

Three process that occur in the nephron

A

= filters blood in kidney

THREE PROCESSES:

  1. Filtration (USWAG
    • urea
    • Salts
    • Water
    • AA
    • Glucose
  2. Reabsorption (USWAG)
    • urea - 0%
    • Salts - Vary
    • Water - Vary
    • AA - 100%
    • Glucose - 100%
  3. Secretion - this is the process where the body actively transports substances from the blood into the nephron - active transport

LEARN PICTURE

23
Q

Nephron structure

A
  • Glomerulus
  • bowman capsule
  • proximal tubule
  • loop of Henele - descending and ascending
  • distal tubule
  • collecting duct
24
Q

The liver

A

= filters blood - detoxifies chemicals and metabolises drugs

  • maintains blood glucose levels
  • produces ketone bodies, aa and nutrients
  • produces transport proteins
  • removes waste products
  • makes bile
25
Q

Hepatic

A

= pertaining to the liver

26
Q

Blood supply to the liver

A

LEARN PICTURE

Oxygenated blood from hepatic artery + Nutrient rich deoxygenated blood from Haptic portal vein

  • Hepatic sinusoids
  • central vein
  • hepatic vein
  • inferior vena cava
  • right atrium of the heart
27
Q

Glucose homeostasis

A

Two important hormones - glucagon/ insulin

  • glucagon causes liver to release glucose
  • insulin causes the liver to store glucose as glycogen
28
Q

Endocrine system

A

= collection of glands that produce hormones that regulate metabolism, growth, development, tissue function, sexual function, reproduction, sleep, mood etc

  • nervous system and endocrine system work together to coordinate all systems if the body
  • maintains homeostasis via the release of hormones from endocrine glands directly into blood
  • most hormones circulate blood and bind to receptors on ‘target cells’
29
Q

Exocrine Glands

A
  • secrete products into ducts

- not hormones

30
Q

Hormones

A

= produced by endocrine gland specific to the hormone produced

31
Q

Hypothalamus and pituitary gland

A
  • work together to control other endocrine glands connected by infundibulum

anterior lobe - secretes 7 hormones

posterior lobe - releases 2 hormones oxytocin and vasopressin ( anti diuretic hormone )

Negative feedback

32
Q

Tropic hormones

A
  • produced in one endocrine gland and regulates the secretion in another
  • TSH stimulates thyroid to produce thyroid hormone (T3 and T4)
  • ACTH stimulates adrenal cortex to produce cortisol
  • FSH - sex hormones
33
Q

Non tropic of anterior pituitary

A
  • growth hormones - stimulates growth, promotes protein synthese and fat metabolism and increase BGL
34
Q

Define deglutition and explain the process?

A

= action and process of swallowing

  • oral cavity
  • oesophagus
  • into stomach