4. Core Immunology

Question 1

Term for an acute potentially life threatening IgE mediated systemic hypersensitivity reaction?

Answer 1

Anaphylaxis

Question 2

A commonly used cytotoxic drug that is a folate antagonist?

Answer 2

Methotrexate

Question 3

Inflammatory cell that is commonly elevated in response to parasitic disease?

Answer 3

Eosinophil

Question 4

X-linked condition associated with a lack of antibodies in the bloodstream?

Answer 4

Agammaglobulinaemia

Question 5

In this condition, there is destruction of thyroid follicles by an autoimmune process?

Answer 5

Hashimoto’s thyroiditis

Question 6

Immunosuppressive drugs with side effects that includes diabetes, hyperlipidaemia, poor wound healing and osteoporosis?

Answer 6

Corticosteroids

Question 7

Anti-mitochondrial Antibody is a specific test for?

Answer 7

Primary biliary cirrhosis

Question 8

Small protein molecules such as interferon and interleukin which are secreted by certain cells of the immune system that can result in inflammation?

Answer 8

Cytokines

Question 9

A cytotoxic drug that commonly causes cystitis?

Answer 9

Cyclophosphamide

Question 10

Anti-CCP is a specific test for?

Answer 10

Rheumatoid arthritis

Question 11

Chimeric monoclonal antibody against CD20- B cell surface used for the treatment of chemotherapy resistant Diffuse Large B Cell Lymphoma?

Answer 11

Rituximab

Question 12

Human infection by this parasite is commonly due to contact with cat faeces?

Answer 12

Toxoplasma gondii

Question 13

Condition in which there are antibodies to acetylcholine receptors?

Answer 13

Myasthenia gravis

Question 14

Condition characterised by Raynaud’s phenomenon, skin thickening and tightening in fingers and face with fibrosis of the internal organs?

Answer 14

Scleroderma