3rd ASSESSMENT Flashcards by Aserah Blank

A partial deficiency of this substance could result to “Fish-eye disease”:

Lecithin:Cholesterol Acyltransferase (LCAT)

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The following drugs alter lipid levels 
• Oral Contraceptive Pills 
• all of the above 
• Postmenopausal Estrogens & Oral Contraceptive Pills only 
• Postmenopausal Estrogens 
• Antihypertensive Drugs

all of the above

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These are risk factors for developing Myocardial Infarction EXCEPT:

physical inactivity
cigarette smoking
Goiter
diabetes mellitus
none of the above

Goiter

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As certaining patient’s cholesterol level, it is important that they be on their usual diet for:

2 Weeks

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Mrs. Brown arrived in an ambulance from the next town after 4days of excruciating and squeezing left chest 
pain. Which of the following tests will be the LEAST useful to confirm the diagnosis of Acute Myocardial 
Infarction at this time? 
• Myoglobin 
• LDH 
• CKMB 
• none of the above 
• AST

CKMB

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The VLDL-C/Triglyceride ratio in patients with this problem is > 0.3:

Dysbetalipoproteinemia

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The following statement describes CORRECTLY chylomicrons & VLDL:
• Chylomicrons forms a creamy top layer, while VLDL leads to turbid serum/plasma
• both Chylomicrons & VLDL forms a creamy top layer
• both Chylomicrons &VLDL leads to turbid serum/plasma.
• all the above
• Chylomicrons leads to turbid serum/plasma, while VLDL forms a creamy top layer.
• none of the above

Chylomicrons forms a creamy top layer, while VLDL leads to turbid serum/plasma

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A blood specimen is drawn for lipoprotein phenotyping. The test results obtained are
Triglyceride, 235 mg/dL (reference range, 40-164 mg/dL)
Total cholesterol, 190 mg/dL(reference range, less than 200 mg/dL)
Prebeta lipoprotein fraction increased
Beta lipoprotein fraction normal
Chylomicrons present
Serum appearance milky
The best explanation for these results would be that the individual exhibited characteristics of
• Type 1 hyperlipoproteinemia
• Type 11 hyperlipoproteinemia
• Type 1V hyperlipoproteinemia
• Type 1 hyperlipoproteinemia & Type 11 hyperlipoproteinemia
• A normal individual

Type 1 hyperlipoproteinemia

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Corneal opacification can occur in patients with this dyslipidemia:

ApoA-1 deficiency and ApoC-III deficiency & ApoA-I variants

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Mr. Smith, 77y.o., came in for an executive check-up. The following are his laboratory results: FBS = 150mg/d
(Normal 50-110mg/dl); Total Cholesterol = 250mg/dL; HDL = 20mg/dL; Creatine Kinase = 120 IU/mL. He
claimed he is well. What is your clinical impression?

Probable diabetic, with increased cholesterol, and normal CK result

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These Dyslipidemia present with high cholesterol, elevated LDL-C, but with normal triglycerides, EXCEPT: 
• Familial hypercholesterolemia 
• Diabetic dyslipidemia 
• Sitosterolemia 
• Family defective apoB

Diabetic dyslipidemia

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A 40 y.o. patient was rushed to the emergency room fur to difficulty of breathing. Chest X-ray show bilateral
pleural effusion. Thoracentesis was done which revealed whitish, cloudy fluid. Which of the following findings
will confirm a Chylothorax condition?
• triglycerides values 2.3mmol/l; cholesterol 7mmol/L
• triglycerides values 1.2 mmol/l; cholesterol 5.5mmol/L
• none of the above
• triglycerides values 2.0mmol/l; cholesterol 5mmol/L
• all the above
• triglycerides values 1.0mmol/l; cholesterol 6.8mmol/L

triglycerides values 2.0mmol/l; cholesterol 5mmol/L

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The signs and symptoms of chylomicron retention disease appear in the first few months of life and they 
include the following EXCEPT: 
• Hypercholesterolemia 
• Failure of weight-gain and growth 
• Diarrhoea & Vomiting 
• none of the above 
• Steatorrhea

Hypercholesterolemia

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A baby was born to a mother who had no prenatal check-up, & who is not sure of her AOG because of
irregular menses. The baby was observed to exhibit deep difficult breathing, & was developing cyanosis
(bluish skin discoloration). Which of these fetal amniotic fluid test results will be the best explanation?
• Lecithin : Sphingomyelin ratio = 2.0
• Lecithin : Sphingomyelin ratio = 1.2
• Lecithin : Sphingomyelin ratio = 2.8
• Lecithin : Sphingomyelin ratio = 1.5
• none of the above
• Lecithin : Sphingomyelin ratio = 2.8 & Lecithin : Sphingomyelin ratio = 1.5

Lecithin : Sphingomyelin ratio = 1.2

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Standing Plasma Test is done to determine by visual inspection.

Chylomicrons

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DESIRED VALUES: Triglycerides

<150mg/dL

Medical disorders that lead to secondary dyslipoproteinemia includes 
• Thyroid Disease & Kidney Disease only 
• Kidney Disease 
• Hepatic Disease 
• All of the Above 
• Thyroid Disease

All

This dyslipidemia present with a High Triglycerides but with normal Cholesterol: 
• Tangier disease 
• Abetalipoproteinemia 
• Familial hypertriglyceridemia 
• Dysbetalipoproteinemia

Familial hypertriglyceridemia

You want to order a Lipid Panel for your walk-in hypertensive patient. However, patient was hesitant to fast overnight and come back the next day since his going out of town & his flight is late afternoon today. Which can be requested immediately without compromising the result?

LDL-C & VLDL-C, Triglycerides and LDL-C
none of the above
Total cholesterol and HDL-C
LDL-C & VLDL-C
Triglycerides and LDL-C
Triglycerides & Total Cholesterol

Total cholesterol and HDL-C

DESIRED VALUES: Total Serum Cholesterol

<100mg/dL
<200mg/dL
<150mg/dL
> 60mg/dL
<60mg/dL

<200mg/dL

Mr. de la Cerna came into the Emergency Room complaining of crushing, and stabbing pain at the Left Chest, radiating to the Left arm. He claimed the pain started an hour ago, and he begs for help. Which result is most likely to increase at this time?

SGOT
all the above
LDH
Troponin I
CK-MB
none of the above

CK-MB

Give the Clinical significance of Chylothorax:

related to some Neoplasms & related to some Infections
none of the above
leakage from the thoracic duct or one of its main tributaries into pleural cavity
related to some Infections
All of the above
related to some Neoplasms

All

Around ____% of myocardial infarction are detected on ECG without the presentation of chest pain.

25%

These drugs can lead to dyslipidemia EXCEPT:

steroids
estrogens
beta-blockers
penicillin

penicillin

Which is the best test to predict coronary heart disease risk? * HDL-cholesterol * Total cholesterol & Total lipids only * Triglycerides * Total lipids * Total cholesterol

Total cholesterol & Total lipids only

Tangier disease is characterized by:

Low HDL

A patient was extracted at 6:00AM for Lipid Profile, with the following results: TAG = 200mg/dL Total Cholesterol = 220mg/dL HDL cholesterol = 35mg/dL Analyze the patient’s LDL & VLDL, using Friedewald Equation:

145.0mg/dL LDL, 40.0mg/dL VLDL

A walk-in patient, Mr. Cruz, who weighs 89kg and whose height is 5’6” came in complaining of occasional chest tightness, and Epistaxis (nosebleeding) for which you requested Prothombin Time. How would you qualify his present BMI?

Obese

Patients with this problem are treated with plasma transfusions during severe hypertriglyceridemia:

ApoC-II deficiency

An individual's lipid and lipoprotein profile should be measured through Standing Plasma Test, ONLY during the following timing: • 2 months after major surgery & when the individual is in a metabolic steady state • when the individual is in a metabolic steady state & Diagnosis is done only after testing at least 2 specimens 2–4 weeks in between. • when the individual is in a metabolic steady state • 2 months after major surgery. • Diagnosis is done only after testing at least 2 specimens 2–4 weeks in between.

When the individual is in a metabolic steady state & Diagnosis is done only after testing at least 2 specimens 2–4 weeks in between.

The Chylomicron particles consist of the following: * triglycerides & phospholipids only * phospholipids * none of the above * triglycerides * cholesterol * All of the above

All

The lecithin/sphingomyelin ratio is a determination that is frequently performed to asses:

Fetal lung maturity

It is recommended by ncep that cholesterol screening be repeated every:

5 years

Mr. Smith, 77y.o., came in for an executive check-up. The following are his laboratory results: FBS = 150mg/d (Normal 50-110mg/dl); Total Cholesterol = 250mg/dL; HDL = 20mg/dL; Creatine Kinase = 120 IU/mL. He claimed he is well. How would the electrophoretogram of Mr. Smith’s blood show his Lactate dehydrogenase (LD) pattern?

LD1 higher than LD2, then followed by LD3, LD4, & LD5 in decreasing height

The following describe Chylomicron retention disease EXCEPT: * associated with mutations in SAR1B gene * autosomal recessive disorder * patient usually obese & associated with mutations in SAR1B gene * patient usually obese * release of chylomicrons in the circulation is inhibited * failure on vitamin D and vitamin E absorption * release of chylomicrons in the circulation is inhibited & associated with mutations in SAR1B gene

patient usually obese

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3rd ASSESSMENT Flashcards

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