3.8.1 - Alterations in DNA base sequence Flashcards
1
Q
What is a gene mutation?
A
Changes to the base sequence of DNA
2
Q
How may a mutation cause a protein to change its structure?
A
- Altered amino acid sequence
- Altered tertiary bonds - ionic, hydrogen, disulphide
- Altered tertiary structure
3
Q
Reasons why mutation may not cause a change in the function of an enzyme
A
- code is degenerate
- amino acid changes but bond doesn’t
- mutation occurs in the introns
- tertiary structure changes but active site doesn’
4
Q
What do deletion, addition and substitution cause?
A
Frame shift
