3.6 Flashcards
Are found on almost every cell in the body plays key roles in embryonic development, and wound repair, and
in immunity.
These sticky glycoproteins act as:
- The molecular Velcro that cells use to anchor themselves to molecules in the extracellular space and to each other
-The arms of migrating cells used to haul them selves past one another
-SOS signal sticking out from the blood vessel lining that rally protective white blood cells to nearby, infected or injured area
-mechanical senses that respond to changes in local tension or fluid movement at the cell surface by stimulating synthesis or degradation of tight junctions
-transmitters of intracellular signals that direct cell migration, proliferation and specialization
Cell adhesion molecules (CAMs)
A huge and diverse group of integral proteins and glycoproteins that serve as binding sites are collectively known as….
Membrane receptors
Are chemicals that bind specifically to plasma membrane receptors
Ligands
Exert their effect indirectly through a G-protein, a regulatory molecule that acts as a middleman or relay to activate [or inactivate] a membrane bound enzyme or ion channel
Gprotein-linked receptors
Proteins that relays signals between extra cellular, first messengers [such as hormones or neurotransmitters transmitters] and intracellular, second messages [such as cyclic AMP] via an effector enzyme
G protein
Intracellular molecule generated by the binding of a chemical [hormone or neurotransmitter] to receptor protein; mediates intracellular responses to the chemical messenger
Second messengers
Intracellular second messengers that mediate the effects of the first [extra cellular] messenger [hormone or neurotransmitter) form from ATP by a plasma membrane enzyme (adenylate cyclase).
Cyclic AMP