33/34: Management of Soft Tissue Infection - Dayton Flashcards
cellulitis =
skin and connective tissue infection and inflammation w/o necrtotic or purulent collections
abscess =
deep tissue infection w/ necrotic tissue and/or purulent collections
involving tissue compartments, joints, tendon sheaths or deep spaces
s/s cellulitis
erythema, edema
pain, fever, chills, malaise
s/s abscess
erythema, edema
fluctuance, purulence, necrosis
pain, fever, chills, malaise
rapid wide spread necrosis with sever systemic symptoms
necrotizing fasciitis
common organisms:
cellulitis
abscess and post op
necrotising fasciitis
puncture wound
diabetic infection
- cellulitis
- strep group A, staph aureus
- abscess and post op
- staph aureus
- necrotising fasciitis
- type 1 = anaerobic, non group A strep
- type 2 = group A strep w/ or w/o staph
- puncture wound
- staph aureus, p. aeruginosa (osteomyelitis)
- diabetic infection
- staph. aureus
what is fever?
greater than 100.5 F
immunocompromised may not mount a febrile response
what is a high WBC
greater than 12 K = leukocytosis
left shift = immature WBC
s/s lymphatic involvement
- inflammatory rxn in lymph channels
- eryhtematous lymphatic streaking
- palpable or painful lymph nodes
SIRS sytemic inflammatory response syndrome =
- temp less than 96.8 or greater than 100.5
- HR greater than 90
- Respirations greater than 20
- PaCO2 less than 32
- WBC less than 4 K or greater than 12 K
sepsis =
severe sepsis =
septic shock =
sepsis = SIRS and documented infection
severe sepsis = sepsis and organ dysfunction
septic shock = sepsis and acute persistent circulatory failure
s/s organ dysfunction
- altered mental status
- edema
- cardiac index greater than 3.5
- acute oliguria
- arterial hypoxemia
- high CR
- INR greater than 1.5
- platelet count less than 100X109
- lactate greater than 1
treatment cellulitis
empiric antibiotics
treatment abscess or necrosis
incision and drainage are priority!
culture technique
- tissue is better than pus
- avoid skin contact to limit confusion of skin flora and pathogens
cellulitis tx
community acquired -
MRSA suspected -
nosocomial -
community acquired: nafcillin, cefazolin, clindamycin
MRSA: TMP/SMZ, clindamycine
Nosocomial: vancomycin
diabetic foot infection tx
mild -
moderate -
mild: dixloxacillin, cephalexin, clindamycin, facillin, cefazolin
moderate: ampicillin/sublactam - clindamycin + levaquin
animal and human bites
non allergic = ampicillin/sulbactam
PCN allergy = clindamycin + levaquin
tx paronychia
- incision and drainage
- antibiotics rarely needed if not immunocompromised
criteria for hospital admission
- profound clinical symptoms (sepsis)
- one or more contributing disease states
- antibiotics requiring inpatient monitoring
- failure of out patient therapy
- suspicion of absces requiring I&D
most important tx abscess
- I&D/culture
then …
- empiric antibiotics
- medical evaluation
- vascualr and other testing
- directed antibiotics afeter cultures are available
- open wound management
- delayed closure or reconstruction
puncture wound tx is based on zone of involvement
- always get an x-ray
- zone 1 = high risk
- zone 2 = low risk
- zone 3 = mod risk