3.1.5.1 Structure of DNA and RNA Flashcards

1
Q

What is a nucleotide?

A

The monomer of nucleic acid (a polynucleotide)

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2
Q

Which three parts is a nucleotide made up of?

A

A phosphate group - gives acidic nature
Pentose sugar - ribose(RNA) and deoxyribose(DNA)
Nitrogenous base - 5 different types

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3
Q

What is the name of the bond formed between nucleotides during a condensation reaction?

A

Phosphodiester bond

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4
Q

How are the phosphodiester bonds bonded between nucleotides?

A

Between carbon 3 of pentose sugar of one nucleotide and carbon 5 of phosphate group of another nucleotide

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5
Q

How do RNA and DNA differ in pentose sugar?

A

RNA - ribose (OH)
DNA - deoxyribose (H)

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6
Q

How do RNA and DNA differ in bases?

A

RNA - AUCG
DNA - ATCG

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7
Q

How do RNA and DNA differ in number of strands?

A

RNA - usually single
DNA - always double

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8
Q

How do RNA and DNA differ in length?

A

RNA - shorter (variable length depending on section copied)
DNA - longer

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9
Q

How do RNA and DNA differ in chemical stability?

A

RNA - less stable
DNA - very stable

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10
Q

What are the three main types of RNA?

A

m(messenger)RNA, t(transfer)RNA, r(ribosomal)RNA

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11
Q

What is the structure and function of mRNA?

A

It is a single stranded, uncoiled polynucleotide with unattached bases
It copies the template(un-coding) strand of DNA code which is exported from the nucleus

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12
Q

What is the structure and function of tRNA

A

It is a single stranded polynucleotide arranged in a clover leaf shape
The top of the tRNA is the amino acid binding site which the anti-codon - found at the bottom of tRNA lines up alongside the appropriate codon on mRNA during protein synthesis

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13
Q

What is it called when a tRNA attaches to an amino acid?

A

It becomes ‘activated’

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14
Q

What is the structure and function of rRNA?

A

It is a long length of RNA produced in the nucleolus
It combines with proteins to form ribosomes in the cytoplasm

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15
Q

What bond holds bases together in a double helix?

A

Hydrogen bonds
A=T, C≡G

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16
Q

What are the two types of bases?

A

Purine(two hexagons) - A,G
Pyrimidines(one hexagon) - C,T,U

17
Q

How are two polynucleotide chains structured?

A

They run anti-parallel to one another

18
Q

What is the chain of sugar and phosphates known as?

A

Sugar-phosphate backbone