3.1 (Quiz 1) Flashcards
Peptidoglycan cell wall material
Gram (+) and (-)
Thicker peptidoglycan cell wall (smooth)
Gram (+)
No outer membrane
Gram (+)
Stain: purple
Gram (+)
No LPS present
Gram (+)
Thinner peptidoglycan cell wall (gagged)
Gram (-)
Cell wall “sandwiched” between cytoplasmic and outer membrane
Gram (-)
Stain: red/pink
Gram (-)
LPS found in outer leaflet of outer membrane
Gram (-)
lipid A portion is highly toxic; variable distal region of exposed carbohydrate is O-antigen and used for serotyping (endotoxin, pyrogen)
LPS
Gram (+) spherical/ovoid cocci, arranged in chains or pairs
Streptococci
Form significant portion of normal microbiota
Streptococci
Most species rarely cause disease
Streptococci
Biochemical properties of Streptococci:
catalase negative
GAS Pathogenesis, major virulence factor
M protein
contagious bacterial skin infection forming pustules and yellow crusty sores
Impetigo (GAS Pathogenesis)
skin infection with formation of pus
Pyoderma (GAS Pathogenesis)
acute infection of skin, involves dermis and lymphatics
Erysipelas (GAS Pathogenesis)
Neonatal infections, capsular polysaccharide
GBS Pathogenesis
Streptococcus pneumoniae principle toxin:
pneumolysin
Cytotoxic to epithelial cells, phagocytic cells:
pneumolysin
In conjunction with H2O2 induces apoptosis during meningitis:
pneumolysin
Largely result of inflammation severity directly proportional to intensity of inflammation:
pneumococcal disease
Pneumococcal disease risk factor:
defective antibody formation
Streptococcal diseases (Group C and G):
skin and throat infections, endocarditis, bone/joint infections
