1.4 (Quiz 1) Flashcards
Single cell layer
Stratum basale (Stratum germinativum)
Attached to basement membrane
Stratum basale (Stratum germinativum)
Mitotically active
Stratum basale (Stratum germinativum)
Many desmosomes
Stratum spinosum
Abundant keratin fibers
Stratum spinosum
Outer layer of Stratum spinosum cells has ___ that contain ___
lamellar bodies, glycolipids
Lamellar bodies of lipid and glycolipid
Stratum granulosum
Keratohyaline granules containing filaggrin
Stratum granulosum
Binding of keratin filaments to form bundles
Stratum granulosum
Waxy cell envelopes containing keratin
Stratum lucidum, Stratum corneum
Clear zone microscopically
Stratum lucidum
Found in thick skin only
Stratum lucidum
major cell type in epidermis
Keratinocytes (cell type of epidermis)
Provides barrier function
Keratinocytes (cell type of epidermis)
Produces Vitamin D precursor
Keratinocytes (cell type of epidermis)
Derived from neural crest
Melanocytes (cell type of epidermis)
Produce melanin pigment
Melanocytes (cell type of epidermis)
Derived from basal layer of epidermis (not neural crest)
Merkel cells (cell type of epidermis)
Mechanoreceptor function
Merkel cells (cell type of epidermis)
Derived from bone marrow cells
Langerhans (dendritic) cells (cell type of epidermis)
Potent antigen-presenting cells for T-lymphocytes
Langerhans (dendritic) cells (cell type of epidermis)
No junctions with keratinocytes
Langerhans (dendritic) cells (cell type of epidermis)
Found in outer stratum spinosum
Langerhans (dendritic) cells (cell type of epidermis)
Migrate into and out of epidermis from dermis
Langerhans (dendritic) cells (cell type of epidermis)
Carry antigens to lymph nodes draining skin via afferent lymph
Langerhans (dendritic) cells (cell type of epidermis)
Important for discriminating shape and texture
Merkel cells (cell type of epidermis)
Afferent nerve axon loses myelin sheath as it penetrated basement membrane
Merkel cells (cell type of epidermis)
Forms a nerve plate at point of contact with Merkel cell membrane
Merkel cells (cell type of epidermis)
Capillary network, Sensory nerve endings (Meissner)
Papillary layer
Sweat glands, Capillary network w/ AV anastomoses, Sebaceous glands
Reticular layer
vascular passage by which blood is diverted from its usual or normal path
shunt
Associated with hair follicles
Sebaceous glands
Branched acinar glands
Sebaceous glands
Holocrine secretion: sebum
Sebaceous glands
Product of dying sebaceous gland cells (lots of lipid)
Sebaceous glands
Substrate for bacteria
Sebaceous glands
Acne: chronic inflammation of sebaceous glands
Sebaceous glands
Thermoregulation and mineral excretion
Eccrine sweat gland
Simple coiled gland
Eccrine sweat gland
Derived from ectoderm
Eccrine sweat gland
Coiled tubular gland-lumen larger than eccrine sweat glands
Apocrine sweat gland
Duct empties into canal of hair follicle
Apocrine sweat gland
Protein rich secretion
Apocrine sweat gland
Pain & temperature
Free nerve ending
non specific Tactile
Meissner corpuscle, Merkel cell
Tactile (hair movement)
Root hair plexus
Tactile (pressure, vibration)
Pacinian corpuscle
nerve endings adjacent to papillae; light touch
Merkel cells
temperature, pain, itch
Free nerve endings
elliptical structure adjacent to papillae; light touch
Meissner corpuscles
concentric lamellae; coarse touch, pressure and vibrations
Pacinian corpuscles