3 - Teratogenesis Flashcards

1
Q

Fetal renal damage

A

ACE inhibitors

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2
Q

Neural tube defects

A

Antiepileptic drugs

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3
Q

Fetal hydantoin syndrome

A

Phenytoin

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4
Q

Neonatal hypoglycemia

A

Oral hypoglycemic agents

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5
Q

Neonatal dependence

A

Baribiturates

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6
Q

Vaginal clear cell adenocarcinoma

A

Diethylstillbestrol (DES)

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7
Q

Fetal alcohol syndrome

A

Ethanol

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8
Q

Ebstein’s anomaly

A

Lithium

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9
Q

Craniofacial malformations

A

Isotretinoin

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10
Q

Congenital hypothyroidism

A

Iodide

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11
Q

Mobius sequence

A

Misoprostol

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12
Q

Cutis laxa

A

Penicillamine

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13
Q

Phocomelia

A

Thalidomide

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14
Q

IUGR

A

Smoking

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15
Q

Tooth discoloration

A

Tetracycline

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16
Q

Ototoxicity

A

Streptomycin

17
Q

Aplasia cutis congenita

A

Methimazole

18
Q

Kernicterus

A

Sulfonamides

19
Q

Cartilage damage

A

Fluoroquinolones

20
Q

Warfarin

  • 1st trimester
  • 2nd trimester
  • 3rd trimester
A
  • chondrodysplasia
  • CNS malformations
  • Bleeding diatheses