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ALCB - Pharma > 1 - DOC > Flashcards

1 - DOC Flashcards

1
Q

Hypertriglyceridemia

A

Fibrates

  • gemfibrozil
  • fenofibrate
  • bezafibrate
  • Activates PPAR-a
  • increase expression of lipoprotein lipase and apolipoprotei
  • lowers TG
  • decrease secretion of VLDL
  • increase HDL
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2
Q

Acute migraine

A

5-HT 1D agonist
- sumatriptan

  • causes vasoconstruction
  • modulates neurotransmitter release
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3
Q

Acute asthma attacks

A

Albuterol/salbutamol

  • B2-selective agonist
  • bronchodilation
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4
Q

Triple therapy for COPD-Asthma overlap

A

LAMA + LABA + inhaled ICS

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5
Q

Asthma prophylaxis

A

Fluticasone

  • corticosteroid
  • inhibitor of phospholipase A2
  • reduces expression of COX
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6
Q

Status asthmaticus

A

IV prednisolone or hydrocortisone

Prednisolone - active metabolite of prednisone

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7
Q

Anticoagulation for pregnancy

A

Heparin

  • activates antithrombin III
  • indirect anticoagulant
  • PTT
  • intrinsic
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8
Q

DMARD of first choice for Rheumatoid Arthritis

A

Methotrexate

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9
Q

1st line for chronic gout

A

Allopurinol

  • xanthine oxidase inhibitor
  • alloxanthine - active metabolite that irreversibly inhibits xanthine oxidase
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10
Q

Gonorrhea

A

Ceftriaxone and Cefixime

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11
Q

Syphilis

A

Penicillin

  • binds to PBP
  • inhibits transpeptidation in bacterial cell walls
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12
Q

Toxoplasmosis

A

Sulfadiazine-Pyrimethamine
- antifolate drug

Pyrimethamine
- co-administered with Leucovorin to limit bone marrow toxicity

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13
Q

DOC for ameobiasis, giardiasis and pseudomembranous colitis

A

Metronidazole

  • nitroimidazole, antiprotozoal
  • MOA: reactive reduction of ferredoxin forminh free radicals that disrupt the ETC
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14
Q

Prinzmetal Angina

A

Diltiazem

  • ND CCB
  • cardiac > vascular
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15
Q

Ventricular arrhythmias

A

Lidocaine
- Class 1B anti arrhythmic

MeLT

  • Mexiletine
  • Lidocaine
  • Tocainide
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16
Q

Paroxysmal Supraventricular Tachycardia

A

Adenosine

17
Q

Prevent fulminant hepatitis in acetaminophen toxicity

A

N-acetylcysteine

18
Q

Diabetic gastroparesis

A

Metoclopramide

19
Q

Seizures in infants

A

Phenobarbital

20
Q

Delirium tremens

A

Long-acting BZD

  • diazepam
  • chlordiazepoxide
21
Q

Opioid overdose

A

Naloxone

22
Q

Opioid dependence and chronic alcoholism

A

Naltrexone

23
Q

Absence seizure

A
  • Ethosuximide (DOC)
  • Valproic acid

2nd line: clonazepam

24
Q

Generalized tonic-clonic seizures

A
  • Phenytoin
  • Carbamazepine
  • Valproic acid
25
Q

Partial seizures

A
  • Phenytoin
  • Carbamazepine
  • Lamotrigine
26
Q

Trigeminal neuralgia

A

Carbamazepine

Other:
- oxcarbazepine

27
Q

Bipolar disorder (acute mania)

A

Valproic acid (first line for mania)

  • Carbamazepine
  • Lamotrigine
28
Q

Status epilepticus

A
  • Lorazepam
  • Diazepam
  • Phenytoin
  • Phenobarbital
29
Q

Malignant Hyperthermia

A

Dantrolene

ALCB - Pharma (13 decks)

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