3 - DNA and Protein Synthesis Flashcards
Define virulent
Disease / has harmful effects
Who did the first experiment for DNA evidence?
Griffiths
Who did the second experiment for DNA evidence?
Avery, Macleod, McCarthy
Who did the third experiment for DNA evidence?
Hershey and Chase
What does DNA stand for?
Deoxyribonucleic acid
What does DNA consists of?
Phosphate group Nitrogenous base (ATCG) Deoxyribose sugar (5 carbon)
What did Chargaff et al discover?
Number of A = number of T
Same with C and G
Name the two types of bases
Purine and pyrimidine
Name the 2 purines
A and G
Name the 2 pyrimidines
T and C (both contain y)
Number of rings in purines
2
Number of rings in pyrimidines
1 ( 1 y 1 ring)
What does ATCG stand for
Adenine
Thymine
Guanine
Cytosine
What bond connects the bases
Hydrogen bonds
How many bonds connects the bases A and T
2
How many bonds connects the bases C and G
3 (George Clooney is 3 stars)
Describe a nucleotide
Phosphate , base , deoxyribose
| O /\ | | / \ \ _ /
Which 2 directions do the nucleotides go?
Carbon 5-3 and Carbon 3-5
Which is bigger : purine or pyramidine
Purine as 3 hydrogen bonds
In which direction are the pentagons upside down?
3-5 or 5-3
Carbon 3-5
5 differences between DNA and RNA
Sugar Deoxyribose Ribose
Bases Thymine Uracil (pyrimidine)
Stands Double + base pairing Single
Helix Yes No
Length Big Smaller – no introns
Who did the DNA replication experiment?
Meselson and Stahl
What type of replication is DNA repiication?
Semi-conservative - half of original is bonded to new stands
Draw semi-conservative replication
11 II
1I I1
1I II II I1