3 chapter (neoplasia) pathoma + FA table IMMUNOHISTOCHEMISTRY 12/02

Question 1

Itermediate filaments. Keratin –> what tissue type

Answer 1

epithelium

Question 2

Itermediate filaments. Epithelium –> what fillament?

Answer 2

Keratin

Question 3

Itermediate filaments. Vimentin –> what tissue type

Answer 3

Mesenchyme

Question 4

Itermediate filaments. Mesenchyme –> what fillament?

Answer 4

Vimentin

Question 5

Itermediate filaments. GFAP –> what tissue type

Answer 5

Neuroglia

Question 6

Itermediate filaments. Neuroglia –> what filament

Answer 6

GFAP

Question 7

Itermediate filaments. Neurofilament –> what tissue type

Answer 7

Neurons

Question 8

Itermediate filaments. Neurons –> what filament

Answer 8

Neurofilament

Question 9

PSA –> tissue type

Answer 9

Prostatic epithelium

Question 10

Prostatic epithelium –>

Answer 10

PSA

Question 11

ER –> tissue type

Answer 11

Breast epithelium

Question 12

Breast epithelium –>

Answer 12

ER

Question 13

Thyroglobulin –> tissue type

Answer 13

Thyroid follicular cells

Question 14

Thyroid follicular cells –>

Answer 14

thyroglobulin

Question 15

Chromogranin (commonly tested) –> tissue type

Answer 15

Neuroendocrine cells (eg small cell carcinoma of lung and carcinoid tumors)

Question 16

Neuroendocrine cells (eg small cell carcinoma of lung and carcinoid tumors) –>

Answer 16

Chromogranin (commonly tested)

Question 17

S-100 –> tissue type

Answer 17

Melanoma, Schwanoma and Langerhans cells histiocytosis

Question 18

Melanoma, Schwanoma and Langerhans cells histiocytosis –>

Answer 18

S-100

Question 19

FA. Chromogranin and synaptophysin. Target cells?

Answer 19

Neuroendocrine cells

Question 20

FA. Chromogranin and synaptophysin. Tumors?

Answer 20

Small cell carcinoma of the lung, carcinoid tumor, neuroblastoma

Question 21

FA. Cytokeratin. Target cells?

Answer 21

Epithelial cells

Question 22

FA. Cytokeratin. Tumors?

Answer 22

Epithelial tumors (eg squamous cell carcinoma)

Question 23

FA. Desmin. Target cells?

Answer 23

Muscle

Question 24

FA. Desmin. Tumors?

Answer 24

Muscle tumors (eg rabhdomyosarcoma)

Question 25

FA. GFAP (glial fibrillary acidic protein). Target cells?

Answer 25

Neuroglia (eg. astrocytes, Schwann cells, oligodendrocytes)

Question 26

FA. GFAP. Tumors?

Answer 26

Astrocytoma, glioblastoma

Question 27

FA. Neurofilament. target cells?

Answer 27

Neurons

Question 28

FA. Neurofilament. tumors?

Answer 28

Neuronal tumors (eg. neuroblastoma)

Question 29

FA. PSA. target cells?

Answer 29

Prostatic epithelium

Question 30

FA. PSA. tumors?

Answer 30

Prostate cancer

Question 31

FA. S-100. target cells?

Answer 31

Neural crest cells

Question 32

FA. S-100. tumors?

Answer 32

Melanoma, schwannoma, Langerhans cell histiocytosis

Question 33

FA. TRAP. Target cells?

Answer 33

tartrate-resistant acidic phosphatase

Question 34

FA. TRAP (tartrate-resistant acidic phosphatase). Tumors?

Answer 34

Hairy cell leukemia

Question 35

FA. Vimentin. Target cells?

Answer 35

Mesenchymal tissue (eg. fibroblast, endothelial cells, macrophages)

Question 36

FA. Vimentin. Tumors?

Answer 36

Mesenchymal tumors (eg. sarcoma), but also many other tumors (eg. endometrial carcinoma, renal cell carcinoma, meningioma).

Question 37

FA. PECAM-1/CD31. Target cell?

Answer 37

Endothelial cells

Question 38

FA. PECAM-1/CD31. Tumors?

Answer 38

Vascular tumors (eg. angiosarcoma)