3 chapter (neoplasia) pathoma + FA table IMMUNOHISTOCHEMISTRY 12/02 Flashcards

1
Q

Itermediate filaments. Keratin –> what tissue type

A

epithelium

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2
Q

Itermediate filaments. Epithelium –> what fillament?

A

Keratin

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3
Q

Itermediate filaments. Vimentin –> what tissue type

A

Mesenchyme

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4
Q

Itermediate filaments. Mesenchyme –> what fillament?

A

Vimentin

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5
Q

Itermediate filaments. GFAP –> what tissue type

A

Neuroglia

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6
Q

Itermediate filaments. Neuroglia –> what filament

A

GFAP

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7
Q

Itermediate filaments. Neurofilament –> what tissue type

A

Neurons

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8
Q

Itermediate filaments. Neurons –> what filament

A

Neurofilament

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9
Q

PSA –> tissue type

A

Prostatic epithelium

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10
Q

Prostatic epithelium –>

A

PSA

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11
Q

ER –> tissue type

A

Breast epithelium

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12
Q

Breast epithelium –>

A

ER

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13
Q

Thyroglobulin –> tissue type

A

Thyroid follicular cells

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14
Q

Thyroid follicular cells –>

A

thyroglobulin

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15
Q

Chromogranin (commonly tested) –> tissue type

A

Neuroendocrine cells (eg small cell carcinoma of lung and carcinoid tumors)

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16
Q

Neuroendocrine cells (eg small cell carcinoma of lung and carcinoid tumors) –>

A

Chromogranin (commonly tested)

17
Q

S-100 –> tissue type

A

Melanoma, Schwanoma and Langerhans cells histiocytosis

18
Q

Melanoma, Schwanoma and Langerhans cells histiocytosis –>

A

S-100

19
Q

FA. Chromogranin and synaptophysin. Target cells?

A

Neuroendocrine cells

20
Q

FA. Chromogranin and synaptophysin. Tumors?

A

Small cell carcinoma of the lung, carcinoid tumor, neuroblastoma

21
Q

FA. Cytokeratin. Target cells?

A

Epithelial cells

22
Q

FA. Cytokeratin. Tumors?

A

Epithelial tumors (eg squamous cell carcinoma)

23
Q

FA. Desmin. Target cells?

A

Muscle

24
Q

FA. Desmin. Tumors?

A

Muscle tumors (eg rabhdomyosarcoma)

25
Q

FA. GFAP (glial fibrillary acidic protein). Target cells?

A

Neuroglia (eg. astrocytes, Schwann cells, oligodendrocytes)

26
Q

FA. GFAP. Tumors?

A

Astrocytoma, glioblastoma

27
Q

FA. Neurofilament. target cells?

A

Neurons

28
Q

FA. Neurofilament. tumors?

A

Neuronal tumors (eg. neuroblastoma)

29
Q

FA. PSA. target cells?

A

Prostatic epithelium

30
Q

FA. PSA. tumors?

A

Prostate cancer

31
Q

FA. S-100. target cells?

A

Neural crest cells

32
Q

FA. S-100. tumors?

A

Melanoma, schwannoma, Langerhans cell histiocytosis

33
Q

FA. TRAP. Target cells?

A

tartrate-resistant acidic phosphatase

34
Q

FA. TRAP (tartrate-resistant acidic phosphatase). Tumors?

A

Hairy cell leukemia

35
Q

FA. Vimentin. Target cells?

A

Mesenchymal tissue (eg. fibroblast, endothelial cells, macrophages)

36
Q

FA. Vimentin. Tumors?

A

Mesenchymal tumors (eg. sarcoma), but also many other tumors (eg. endometrial carcinoma, renal cell carcinoma, meningioma).

37
Q

FA. PECAM-1/CD31. Target cell?

A

Endothelial cells

38
Q

FA. PECAM-1/CD31. Tumors?

A

Vascular tumors (eg. angiosarcoma)