2S [LEC]: Myelodysplastic Syndrome Flashcards
1
Q
Group of morphological abnormalities common in elderly patients
A
Myelodysplastic syndromes
2
Q
T/F: Myelodysplastic syndromes are heterogenous and affects all cell lines
A
True
3
Q
Low frequency in BM with one or more somatic mutations
A
Phenotypically normal HSC
4
Q
Complex interaction with somatic mutation, epigenetic modification, BM microenvironment, and environmental stimuli that has a risk of transformation to MDS
A
Clonal hematopoiesis of indeterminate potential (CHIP)
5
Q
A