2S [LEC]: Myelodysplastic Syndrome Flashcards

1
Q

Group of morphological abnormalities common in elderly patients

A

Myelodysplastic syndromes

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2
Q

T/F: Myelodysplastic syndromes are heterogenous and affects all cell lines

A

True

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3
Q

Low frequency in BM with one or more somatic mutations

A

Phenotypically normal HSC

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4
Q

Complex interaction with somatic mutation, epigenetic modification, BM microenvironment, and environmental stimuli that has a risk of transformation to MDS

A

Clonal hematopoiesis of indeterminate potential (CHIP)

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5
Q
A
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