2S [LAB]: ESR Flashcards
Refers to the speed of settling of RBCs in anticoagulated blood
ESR
Measures the distance and speed of fall of RBCs in plasma in a tube of a standard bore and length after standing perpendicularly
ESR
Most important factor influencing ESR
Plasma proteins
How many minutes is the initial period of aggregation or rouleaux formation in ESR determination?
10 mins
How many minutes is the period of fast settling in ESR determination?
40 mins
How many minutes is the final period of packing in ESR determination?
10 mins
Most commonly used manual method of ESR determination
Modified Westergren Erythrocyte Sedimentation Rate
Method of ESR determination recommended by the International Council for Standardization in Hematology and CLSI
Modified Westergren Erythrocyte Sedimentation Rate
ESR determination method that uses two sides (0-10 and 10-0)
Wintrobe-Landsberg Method
The most sensitive method of ESR determination
Westergren method
ESR determination that can be used for the serial study of chronic diseases like TB, carcinoma, and others
Westergren method
Normal value in Wintrobe-Landsberg method
M: 0-10 mm/hr
F: 0-20 mm/hr
Normal value in Westergren method
M: 0-15 mm/hr
F: 0-17 mm/her
Anticoagulant of choice in Graphic or Cutler method of ESR determination
3.8% sodium citrate
Volume of blood used in Graphic or Cutler method of ESR determination
0.8 mL
Anticoagulant of choice in Linzenmeier method of ESR determination
3% sodium citrate
Tube used in ESR determination that is 65 mm in length, 5 mm in diameter, and has a capacity of 1 mL
Linzenmeier
Anticoagulant of choice in Bray’s method of ESR determination
1.3% sodium citrate
Tube used in ESR determination that can be used for hematocrit and LE cell preparation
Bray’s tube
An ESR determination method that is a modification of Linzenmeier-Raunter method
Micro Landau
A tube used in ESR determination that is calibrated 0-50 mm and has two graduation marks, one at 12.5 mm and another at 62.5 mm, with a small bulb similar to RBC and WBC pipettes
Micro-Landau tube
ESR determination method used for infants and children when venipuncture may not be practical
Smith Micro
In automated ESR system by Vega Biomedical, the determination takes only how many minutes to finish?
22 mins
The automated ESR system by Vega Biomedical is comparable to which ESR determination method?
Westergren method
Automated ESR system by Vega Biomedical:
Four samples at one time
Mini-Ves
Automated ESR system by Vega Biomedical:
20 samples at one time; print results
Ves-Matic
Automated ESR system by Vega Biomedical:
60 samples at one time, print results and identifies sample by a barcode readers
Ves-Matic 60
Identify the effect in ESR determination:
Tilted column
False increase
Identify the effect in ESR determination:
Hemolysis
False increase
Identify the effect in ESR determination:
Increased room temperature
False increase
Identify the effect in ESR determination:
Clotted sample
False decrease
Identify the effect in ESR determination:
Excess anticoagulant
False decrease
Identify the effect in ESR determination:
Old blood
False decrease
Identify the effect in ESR determination:
Chronic inflammatory conditions
Increased
Identify the effect in ESR determination:
Bacterial infection
Increased
Identify the effect in ESR determination:
Tissue damage
Increased
Identify the effect in ESR determination:
Severe anemia
Increased
Identify the effect in ESR determination:
Pregnancy
Increased
Identify the effect in ESR determination:
Polycythemia
Normal to decreased
Identify the effect in ESR determination:
Sickle cell anemia
Normal to decreased
Identify the effect in ESR determination:
Spherocytosis
Normal to decreased
Identify the effect in ESR determination:
Conditions with poikilocytosis
Normal to decreased
Length of Westergren tube
30 cm
Bore of the Westergren tube
2.5 cm
T/F: Westergren tube has an open bottom
True
T/F: Wintrobe tube has an open bottom
False
Calibration of Westergren tube
0-200 mm
Anticoagulant of choice in Westergren method
3.8% trisodium citrate
Length of Wintrobe tube
11.5 cm
Bore of the Wintrobe tube
3 mm
Anticoagulant of choice in Wintrobe method
Hellen and Paul’s double oxalate