2E regulation of the ceronary blood flow angina myocardial infarction and heart failure Flashcards
what are the two major variable in blood flow through the arteries
pressure and resistance (Q=ChangeinP/R
what is the major influence on the resistance of blood flow
radius of the artery
vasodialation vs vasoconctriction in restriction
you know this
where is the blood supply to my myocarduim derive from
the right and left coronary arteries
left coronary artery flows where
to the curumflex and to the left anterior descending
where the the right coronary artery flow
the the right marginal artery and the posterior descending
what drives blood flow throuhg the coronary vessels and perfuses the myocardium
aortic pressure
what is a major factor in causing changes in CBF (coronary blood flow)
changes in coronary resistance
what are two major “normal factors that influence coronary constriction
Nerual and Metabolic
what causes ischemic heart disease
the imbalance between supply and demand of oxygen(supply<demand)
what are the three major reasons for decreased supply
-hemodynamic factors
-cardiac factors
valve disease
increased heart rate
-heatologic factors
anemias
poisons
what are the three physiologic causes in IHD
myocardial hypertrophy
overcoming excessive preload
overcoming excessis afterload
angina perctoris
episodic chest pain caused by inadequate oxygenation of the myocardium
what are the types of angina
- classic angina or exertional angina
- unstable angina
- myocardial infarction
- variant angina or prinsmetal’s angina (vasopsastic angina)
what are the two types or myocardial infarctions
transmural infarction
subendocardial infarction
