2.9 Neurological and Sensory SEIZURE Flashcards

1
Q

What are seizures?

A

Seizures occur when there is abnormal electrical discharge in the neurons in brain.

Temporary.

Disturbs skeletal muscle function, sensation, autonomic function, behavior and/or consciousness.

Epilepsy = recurring seizures, variable frequency. Prevalence & incidence increases in older adults

Occurs when there is an imbalance in excitatory (Neurotransmitter=glutamate) and inhibitory (Neurotransmitter= GABA) neurons in areas of the cerebral cortex (focal) or the entire cerebral cortex (generalized).

Many factors can alter the membrane potential & increase risk of hyperactive response of neurons.

Everyone has a seizure threshold and pathologic processes can lower it.

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2
Q

What are seizures? Risks/Triggers

A

Risks/Triggers: fatigue, fever, hypoglycemia, acid/base imbalance, IICP, tumors, ETOH, meds, constipation, hyperventilation, menses as well as individual factors like flashing lights, certain odors, music/sounds

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3
Q

Stages of seizures

A

PRODROMAL – can begin days before for some pts individual: emotional changes, fatigue, GI, urinary symptoms

AURA – immediately prior to onset of seizure for some types of seizures individual: smells, vision change, auditory hallucination

ICTUS – actual seizure event

POST-ICTUS – recovery after seizure variable length of time (can be up to days), initially unconscious, confusion, fatigue, sleepiness

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4
Q

Focal seizures (“partial”)

A

Start in, and affect, one hemisphere (sometimes just a small area of one lobe)

Manifestations are dependent on area of the brain affected:

  • May remain conscious, but can be altered
  • Motor: recurrent muscle contraction of the face or contralateral part of the body (often hands)
  • Sensory: abnormal sensations, smells, tastes, numb/tingling, hallucinations
  • Autonomic : tachycardia, flushing, hypo/hypertension, psychic sensation like Déjà vu, emotions

May be preceded by an aura (which is different than prodromal symptoms that can happen days before)

Can progress to generalized seizures

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5
Q

Generalized seizures

A

Affect both sides of the brain and deeper brain structures

Loss of consciousness

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6
Q

Generalized seizures ABSENCE

A

ABSENCE: (more common in children)
brief cessation of motor activity
blank stare, unresponsive
Automatisms & eyelid fluttering may occur

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7
Q

Generalized seizures

Tonic clonic

A

TONIC-CLONIC (grand-mal):
most common type, last 60-90 seconds
Aura is possible and pt will experience sudden loss of consciousness

Tonic phase: muscles rigid, often cry out, arms & legs extended & back is arched, jaw clenched, incontinence of bladder/bowel possible, breathing ceases, become cyanotic

Clonic phase: alternating contraction and relaxation of extremities, hyperventilation, eyes roll back, frothing at mouth, subsides gradually

Post ictal phase – unconscious and unresponsive to stimuli, event amnesia

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8
Q

Precautions for pts at risk for seizure

A

Think about who might be at risk – can happen anywhere

ETOH withdrawal, high fever, CNS infection, substance abuse, any history of epilepsy, Alzheimer’s, head trauma, CVA hx.

Make sure you have a functional IV access in acute care

Suction, oxygen available

Padded bed rails
Keep bed in low position

Ask your pt with seizure history about triggers, prodromal/aura associated

Any change to seizure med orders? NPO? Drug levels?

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9
Q

Assessment during seizure

A

What was the pts LOC? If consciousness was lost, at what point?
Indicates area of brain involved and type of seizure

What was the pt doing just before the attack?
May suggest precipitating factors

In what part of the body did the seizure start?
Can indicate site of seizure activity in the brain tissue

Was there an epileptic cry?
Usually indicates tonic stage of generalized tonic-clonic seizure

Were there any automatisms such as eyelid fluttering, chewing, lip smacking or swallowing?
Often seen in complex, partial, and absence seizures

How long did movements last? Did the location of character change(tonic/clonic?) Did movements involve both sides of the body of just one?
Indicates areas in which focal activity originated

Did the head and/or eyes turn to one side?
Helps localize focus of seizure

Were there changed in pupil reaction?
Indicates involvement of autonomic nervous system

If the pt fell, was the head hit?
May need to rule out subdural hematoma/fracture

Was there foaming/frothing from the mouth?
Was there urinary or bowel incontinence?
Usually indicates tonic-clonic seizure

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10
Q

Nursing Interventions during seizure

Support airway

A

Support airway, breathing, and circulation
have oxygen and suction available
turn patient to side to allow secretions to drain while maintaining airway

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11
Q

Nursing Interventions during seizure

Stay with patient

A

Stay with patient
observe seizure activity
note time and duration – if more than 5 min risk for status epilepticus
assess behavior at the onset of seizure: if the patient experienced an aura, a change in facial expression occurred, and progression of movements
note and document: type, characteristics, and progression of movements
administer intravenous medications as prescribed to stop the seizure
watch for incontinence

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12
Q

Nursing Interventions during seizure

Keep patient safe from injury

A

Keep patient safe from injury
keep bed locked and in low position with padded side rails
if patient is standing or sitting place on bed and protect head and body
loosen clothing from around neck
do not hold patient down

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13
Q

Nursing Interventions during seizure

POST SEIZURE

A

POST SEIZURE
monitor behavior, VS
level of consciousness, motor ability, and speech ability

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14
Q

Diagnosis
Seizure
EEG

A

ELECTROENCEPHALOGRAM (EEG)
Helps localize any brain lesions and confirm the diagnosis, assesses brain activity
No caffeine X8 hrs, withhold seizure meds or other meds impacting CNS, clean, dry hair
May have sleep restrictions

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15
Q

Diagnosis
Seizure
LUMBAR PUNCTURE

A

LUMBAR PUNCTURE
To assess spinal fluid for CNS infections (increased WBCs)
or tumors (increased protein)

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16
Q
Diagnosis
Seizure
MRI or CT Scan
SKULL X-RAY
PT HISTORY
A

MRI or CT Scan
To determine abnormalities in the brain

SKULL X-RAY
to identify any bone abnormalities

PT HISTORY

17
Q

Seizure Medications

INFO

A

Goal is to reduce or prevent seizure activity without impairing cognitive function or producing undesirable side effects. Lowest effective dose.

Not a cure

Anti-seizure drugs have been associated with suicidal thoughts and behavior.

18
Q

SEIZURE MEDICATIONS

POTENTIATE GABA

A

POTENTIATE GABA (GABA is the inhibitory neurotransmitter)

Benzodiazepines (—pam, lorazepam, diazepam) very effective IV in acute seizure, status epilepticus

Barbituates (phenobarbital, primidone)

Gabapeninoids (gabapentin, pregabalin)

SIDE EFFECTS: drowsiness, respiratory depression, ataxia, hypotension

**All these meds reduce activity in the motor cortex neurons & may have CNS effects

19
Q

SEIZURE MEDICATIONS

SUPPRESS SODIUM INFLUX INTO CELLS

A

SUPPRESS SODIUM INFLUX INTO CELLS (stops Na channel activation, limits action potential of neuron= ↓firing)

Levetiracetam - attaches to SV2A on the surface of the neuron vesicles, and that this attachment reduces the backlog of signals that cause a seizure.

Phenytoin – restricts sodium entry gum hyperplasia is a thing, Need good oral and dental care.

Sodium valproate – not safe for women of childbearing age

**All these meds reduce activity in the motor cortex neurons & may have CNS effects

20
Q

Seizer

Other options for tx

A

Surgery
Remove foci surgically
Implanted Vagus nerve stimulator
Deep brain stimulator

Ketogenic diet

Cannabis

21
Q

Vagus nerve stimulation

what is it?

A

Vagus nerve stimulation (VNS) therapy is atreatment for epilepsy that involves a stimulator (or ‘pulse generator’) which is connected, inside the body, to the left vagus nerve in the neck. The stimulator sends regular, mild electrical stimulations through thisnerve to help calm down the irregular electrical brain activity that leads to seizures. VNS therapy aims to reduce the number, length, and severity of seizures. For some people, their seizures become much less frequent, for some it may reduce their seizures a little, and for others it has no effect. VNS therapy may reduce the length or intensity of seizures but this does not happen for everyone. It may also reduce the time it takes to recover after a seizure. It is unlikely to completely stop seizures and it does not ‘cure’ epilepsy