29. Functions of different types of T lymphocytes. Flashcards
1
Q
T killers
A
- have surface prtotein cD8, help recognize MHC 1 receptors
- CD8 is a co receprtor for MHC 1
- recognize antigens through TCRs on the virus infected
- secrete perforins, lymphokines
- induce apoptosis
2
Q
Perforin and granzymes
A
T killer cells secrete perforins and granzymes
Perforin open pores in membrane of the largest cells granzyme enters, this induces apoptosis
3
Q
T helper
A
- have surface protein CD4 - its a coreceptor for MHC2
- B cells differentiate into plasma cells and synthesize antibodies
- peptides are enogenous
***watch vid on how T killer cells work and how