29 Bacterial Infections of the LRT 2 Flashcards

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1
Q

bronchopneumonia

A

atypical pneumonia

bronchi filled with pus, not isolated to one entire lobe

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2
Q

bacterial causes of walking pneumonia

A
  1. mycoplasma pneumoniae
  2. chlamydophila pneumoniae

also (chlamydophil psittaci, coxiella burnettii)

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3
Q

toxic pneumonia

A

legionella pneumophila

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4
Q

broncopneumonia with gradual onset

  • fever, headache, fatigue, muscle ache, dry cough with scant/watery sputum
A

atypical pneumonia

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5
Q

treatment for atypical pneumonia

A

tetracycline and erthromycin

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6
Q

no peptidoglycan

A

mycoplasma

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7
Q
  • culture requires supplementation with sterols and nucleotide precursors
  • fried egg colony morphology
A

mycoplasma pneumoniae

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8
Q

mycoplasma virulence factor

A

P1 adhesin

-binds to base of cilia -> ciliostasis -> epithelial cell damage/death -> defect in mucociliary clearance

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9
Q
  • bronchopneumonia with gradual onset
  • anemia
  • positive cold agglutinin test
A

mycoplasma pneumoniae

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10
Q

treatment for mycoplasma pneumoniae

A

tetracycline and macrolide (erthromycin)

NO BETA LACTAMS

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11
Q

treatment for chlamydophila pneumoniae

A

tetracycline and macrolide

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12
Q

chlamydophil pneumoniae appearance

A

gram negative obligate intracellular pathogen

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13
Q

causative agent of legionnaire’s disease

A

legionella pneumophila

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14
Q

causative agent of pontiac fever

A

legionella pneumophila

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15
Q

characteristics of legionella pneumophila

A

gram negative
inside cells: coccobacilli
outside cell: pleomorphic

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16
Q

grows in high humidity and on charcoal yeast agar

A

legionella pneumophila

-mainly exist as parasites of amoeba

17
Q

outbreaks associated with air conditioning and respiratory therapy devices

A

legionella pneumophila

18
Q

virulence and pathogenesis of legionella pneumophila

A
  • target and attach to alveolar macrophages using pili flagella and numerous proteins
  • coiling phenomenon upon entry
19
Q

toxic pneumonia with patchy infiltrates on CXR

  • chills , pleurisy, comiting , diarrhea, confusion, delirium
  • progressively ill over 3-6 days
  • elevated WBC ceount
A

legionella pneumophila

20
Q

legionella treatment

A

NO beta lactams

macrolide of fluroquinolone