Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Jaspie - Pharmacology > 29 - Antihelminthic drugs > Flashcards

29 - Antihelminthic drugs Flashcards

1
Q

DOC for Ascariasis;

A

Albendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

DOC for Trichuris trichiura (whipworm)

A

Mebendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

MOA of Albendazole?

A

inhibits microtubule assembly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

MOA of Mebendazole?

A

selectively inhibits microtubule synthesis and glucose uptake in nematodes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

DOC for Hydatid disease

A

Albendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

DOC for Necator americanus and Ancylostoma duodenale?

A

Albendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

DOC for Enterobius vermicularis

A

Pyrantel palmoate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

DOC for Strongyloidiasis

A

Ivermectin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

DOC for Filariasis

A

Diethylcarbamazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

MOA for pyrantel palmoate

A

Stimulates the nicotinic receptors of the neuromuscular junction of nematodes, causing depolarization-induced paralysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

DOC for Trichinosis

A

Thiabendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What antihelminthic drug is contraindicated with patients with hepatic dysfunction?

A

Pyrantel palmoate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

MOA for Ivermectin

A

Intensifies GABA-mediated neurotransmission in nematodes, immoblilizing the parasites.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Enumerate: drugs that can cause the Mazotti reaction (2):

A

Diethylcarbamazine (when treating onchocerciasis) and Ivermectin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What kind of drugs must be avoided when treating with Ivermectin?

A

-other drugs that enhance GABA activity, e.g. barbiturates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

DOC for Capillaria philippinensis:

A

Albendazole

17
Q

MOA for Thiabendazole:

A

selectively inhibits microtubule synthesis and glucose uptake in nematodes.

18
Q

DOC for Schistosoma japonicum:

A

Praziquantel

19
Q

DOC for Paragonimiasis:

A

Praziquantel

20
Q

MOA of Praziquantel:

A

Increases membrane permeability to calcium, causing muscle paralysis, vacuolization, and death.

21
Q

DOC for echinococcus granulosus:

A

Albendazole

22
Q

DOC for Taenia solium:

A

Praziquantel

23
Q

DOC for Taenia saginatta

A

Praziquantel

24
Q

Alternative drug for cestode infections:

A

Niclosamide

25
Q

Mechanism of action of Niclosamide

A

uncouples oxidative phosphorylation or by activating ATPases

Jaspie - Pharmacology (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions