23/10 Flashcards
amnesia
the loss of memory which is inconsistent with ordinary forgetting. generally causes difficulty accessing information from the ltm or have difficulty forming new memories
anterograde amnesia
the loss of the ability to form or store new long-term memories (mostly explicit). associated with damage to the medial temporal lobe, particularly the hippocampus and connections between the temporal lobe and frontal lobes
what causes anterogade amnesia
- failure of memory encoding and storage due to disruption of consolidation
- lack of integration into ltm
retrograde amnesia
loss of memory before a trauma
alzheimer’s
a type of dementia characterised by the gradual widespread degeneration of brain neurons
- outer part of the brain is usually affected first
- stm loss is one of the first symptoms
- as the disease progresses, ltm is increasingly impaired
- primarily explicit memories
alzheimer’s early symptoms
- moderate memory loss
- confusion
- unusual irritability
- impaired decision making
- needing to be prompted about social care tasks
alzheimer’s later symptoms
- inability to recognise family members or regular carers
- forgetting one’s own identity
- severe personality changes
alzheimer’s effect on memory
- both retro and anterograde amnesia
- episodic (forgetting part or all of a specific event)
- semantic (forgetting known information such as names for objects or words)
- spatial (inability to remember or follow written or verbal directions)
- procedural (inability to perform everyday tasks)
alzheimer’s brain damage
- cortical and sub-cortical areas look shrivelled due to death of neurons
- median temporal lobe most affected, particularly hippocampus
main cause of neuron death in alzheimer’s
accumulation of plaques and neurofibrillary tangles
plaques
- fragments of the protein beta amyloid
- form hard clumps outside and around the neurons
tangles
- inhibit transport of essential substances throughout the neuron
- formed from a protein called tau
BAC of 0.05
- impaired cognition
- decreased concentration
- exaggerated or inappropriate reactions
BAC and sleep deprivation
- 17 hours is roughly 0.05
- 24 hours is roughly 0.1