224 unit 1 Flashcards
Hypertonic Solution
A solution with an osmolality higher than that of serum
Hypotonic Solution
A solution with an osmolality lower than that of serum
Isotonic Solution
A solution with the same osmolality as serum and other body fluids
Osmosis
The process by which fluid moves across a semipermeable membrane from an area of low solute concentration to an area of high solute concentration
Tonicity
Fluid tension or the effect that osmotic pressure of a solution with impermeable solutes exerts on cell size because of water movement across the cell membrane
Active Transport
hysiologic pump that moves fluid from an area of lower concentration to one of higher concentration; active transport requires ATP for energy
Diffusion
The process by which solutes move from an area of higher concentration to one of lower concentration; does not require energy
Homeostasis
maintenance of a constant internal quilibrium in a biologic system that involves positive and negative feedback mechanisms
Hydrostatic Pressure
The pressure created by the weight of fluid against the wall that contains it.
acidosis
imbalance with increase H+ concentration
alkalosis
imbalance with reduce H+ concentration
Kidney Functions
- regulation of ECF volume and osmolality by selective retention and excretion of body fluids
- regulation of normal electrolyte levels in the ECF by selective electrolyte retention and excretion
- regulation of pH of the ECF by retention of hydrogen ions
- excretion of metabolic wastes and toxic substances
Hypovolemia (Fluid Volume Defecit)
This occurs when loss of ECF volume exceeds the intake of fluid; occurs when water and electrolytes are lost in the same amount as they exist in normal body fluids
Hypovolemia Signs & Symptoms
- acute weight loss
- decreased skin turgor
- oligoria (abnormally small amounts of urine)
- low CVP
- low BP
- dizziness
- weakness
- thirst/confusion
- increased pulse
- muscle cramps
- sunken eyes
- nausea
- increased temp.
- cool, clammy, pale skin
Hypovolemia Contributing Factors
- vomiting
- diarrhea
- fistulas
- fever
- excess sweating
- burns
- blood-loss
- GI suction
- anorexia
- nausea
- diabetes insipidus
Hypovolemia Lab Findings
- increased hgB
- increased hematocrit
- increased BUN
- increased creatinine
Hypovolemia Management
- monitor daily weights
- intake/output
- vital signs
- skin turgor
- mucous membrane assessments
Hypervolemia (Fluid Volume Excess)
Abnormal retention of water and sodium; mostly secondary to increase in the total body sodium content
Hypervolemia Signs & Symptoms
- acute weight gain
- peripheral edema and ascites
- distended jugular veins
- crackles
- elevated CVP
- shortness of breath
- increased BP
- bounding pulse/cough
- increased respiratory rate
- increased urine output
Hypervolemia Lab Findings
- decreased hgB
- decreased hematocrit
Hypervolemia Management
- restricted sodium diet
- intake/output
- promote rest
- diuretics
- daily weight
Serum Sodium Level
135-145
- sodium is the primary determinant of ECF volume and osmolality
- major role in controlling water distribution throughout the body
- regulated by ADH, thirst, and the renin-angiotensin-aldosterone system
Patients at risk for sodium imbalance
older patients, patients with AIDS, those on mechanical ventilation
Hyponatremia (Sodium Defecit)
Serum sodium level less than 135
Hyponametria Contributing Factors
- loss of sodium as in use of diuretics
- loss of GI fluids
- renal disease
- adrenal insufficiency
- gain of water; excessive admin of D5W and hypotonic feedings
- head trauma
- oat-cell lung tumor
- meds assoc. with water retention (oxytocin)
- hyperglycemia
- heart failure
Hyponametria Signs & Symptoms
- anorexia
- nausea/vomiting
- headache
- lethargy
- dizziness
- confusion
- muscle cramps/weakness
- muscular twitching
- seizures
- dry skin
- increased pulse
- low BP
- weight gain
- edema
Hyponatremia Management
- sodium PO if tolerable
- lactated ringer’s solution; isotonic saline (0.9%)
- restricting fluid
- foods/fluids w/ high sodium content
Hypernatremia (Sodium Excess)
Sodium level higher than 145
Hypernatremia Contributing Factors
- water deprivation in patients unable to drink at will
- hypertonic tube feedings w/o adequate water supplements
- diabetes insipidus
- heatstroke
- hyperventilation
- watery diarrhea
- burns
- diaphoresis (excessive sweating)
- excess sodium bicarbonate
- excess sodium chloride administration
- excess corticosteroids
Hypernatremia Signs & Symptoms
- thirst
- elevated temp.
- swollen dry tongue; sticky mucous membranes
- hallucinations
- lethargy
- restlessness
- irritability
- seizures
- pulmonary edema
- twitching
- nausea
- vomiting
- anorexia
- increased pulse
- increased BP
Hypernatremia Interventions
- hypotonic solution (0.3% sodium chloride)
- isotonic non-saline solution D5W
- diuretics
Serum Potassium Level
- 5-5
- potassium is important neuromuscular function
- influences both skeletal and cardiac muscle activity