22. Visual system Phys Flashcards
loss of cone vision —
legally blind
loss of rod vision—
night blindness
what is the sensititivity and resolution associated with rods
high sensitivity ; low resolution
many rods converge to 1 bipolar cell (some bipolar cells interact with amacrine cells)
what is the sensititivity and resolution associated with cones
best resolution, poor sensitivity
one cone to one bipolar cell
what is the path for dark current (on center)
less photons stimulating photoreceptor –> cell depolarize bc more glutamate released –> onto on-center bipolar cells (mGluR6) –> increased inhibition –> close cation channels –> bipolar cell hyperpolarization –> less Glu released from bipolar –> ganglion cell
= dark
what is path for light on on-center bipolar cells
increased photon –> less Glu onto on-center bipolar cell –> less inhibition –> increase cation channels open –> depolarize bipolar cells –> release glutamate onto ganglion cell
cone cells
characteristic of mGluR6
Gi GPCR
when glutamate bind –> it DECREASES cation influx by closing cyclic GMP gate Na channels
(high Glu –> close channel & on-center bipolar cell inactivated)
how do off-center bipolar cells work
activation of receptor in center of bipolar cell receptive field ==> hyperpolarization
use non-NMDA receptors- open and depolarizes
what are ganglion cells
also on- & off- center
- have NMDA or non NMDA
- use action potential
if associated bipolar cell is depolarized –> it releases glutamate –> depolarizes ganglion cell
what are amacrine cells
inhibitory - release gly or gaba
-allow vision in low light to enhance edges, shadows & contrasting areas
lateral geniculate body
signals from 2 eyes are kept apart (direct target retina)
control motion of eyes to converge
control focus of eyes based on distnce
determine relative position
detect movement relative to an object
superior colliculus
make visual map to activate appropriate motor responses to move eyes to intended position
coordinate head & eye movement to visual targets
pretectum
reflex control of pupil/lens
send projection to edinger westphal then to ciliary ganglion
hypothalamus job in vision
retinohypothalamic tract - terminate in supraoptic, suprachiasmatic & paraventricular nuclei of hypothalamus
light -dark entrainment and circadian rhythms
medial temporal area (V5)
neurons that selectively to the direction of a moving edge
tract motion acress scene
ignore color
accessory optic system
advanced visual processed
role in eye movement of compensation & pursuit (esp alternation w saccadic type eye movement for prolonged watching of large field motion)
primary visual cortex (V1)
crude vision/general shape
-size, orientation, local direction of movement & binocular disparity
located in occipital lobe (retinotopic organization)
mostly excitatory (glutamatergic)
damage –> wont see color conscious/subconscious
visual association cortex (v2)
depth perception
analyze disparity btn 2 eyes
V3a
identify when motion is occuring
V4
process color inputs
damage: dont see color but still see shape if diff colors are present ( subconcious level)
ocular dominance column
all 6 layers of cortex
column that responds to input from one eye to other
orientation column (V1)
all 6 layers
organized by visual line stimuli of varying angles
oriented perpendicular to cortical surface
blobs V1
all 6 layers
sensitive to color assembles into cylindrical shape
all 3 color coding required
achromatopsia
damage to specific extrastriate cortical areas
- pat is unable to see info supplied by retina
melanopsin ganglion cells
intrinsically photosensitive
join rods & cones
project to suprachiasmatic nucleus of hypothalamus, nucleus of pretectum and limbic system (regulate mood)
what is the ventral striate pathway
the “what” pathway
V1 - thru V2 - V4 - temporal love
-interpret images
facial recognition
selectively activated by shape, color, textrue & object recognition
what is the dorsal striate pathway
“where” pathway
V1 - thru V2 & V3 - MT/V5 - parietal lobe
associate vision with movement
selectively activated by direction & speed
agnosia
see an object but unable to copy/identify
inability to construct or draw visual stimuli or cant recognize picture
prosopagnosia
type of agnosia
CAN recognize face, its parts and facial expression BUT CANNOT recognize whose face it is