2.2:8 Minerals and trace elements Flashcards
What is the energy balance mainly regulated by?
Control of food intake affected by: hunger and appetite appetite satiation satiety
What region of the brain controls food intake?
Hypothalamus
What is the role of the arcuate nucleus (ARC0 in the hypothalamus?
Integration of appetite signals
IS the ARC region of the brain protected by the BBB and what are the consequences of this?
No, therefore, allows hut hormones to pass into the brain
What peptides activate orexigenic neurons to stimulate food intake?
NYP
AgRP
What peptides activate Anorexigenic neurons to inhibit food intake?
POMC
CART
When POMC undergoes posttranslational modifications what does ot generate?
Melanocortins which act on melanocortin receptors
Where is leptin released from and does it inhibit or stimulate food intake?
Adipose tissues and inhibits food intake
When is PYY released and does it inhibit or stimulate food intake?
Released on eating food and inhibits food intake
Can also act on the pancreas to stimulate insulin which an also inhibit food intake
What does CCK act on and does it inhibit or stimulate food intake?
Acts on the hypothalamus and vagus nerve and inhibits food intake
Where is ghrelin released from and does it inhibit or stimulate food intake?
Released from the GIT and stimulates food intake
what does PYY act on?
NPY Y2 receptor