2.1.6 Cell division, cell diversity and cellular organisation COMPLETE Flashcards
Structure of a chromosome
- Tips are the Telomere
- Centre held together by a centromere
- Protein is wound around histones
The cell cycle order
- Interphase
- Prophase
- Metaphase
- Anaphase
- Telophase
Proper meteors always telephone
Interphase
Mitosis
DNA is uncoiled and not visible
DNA replication occurs
Cell size increases so more cytoplasm, organelles and chloroplast
Prophase
Mitosis
Chromosomes becomes visible as they shorten and thicken.
Centrioles move towards the opposite poles
Microtubules develop
Nuclear envelope breakdown
Metaphase
Mitosis
Chromosomes line up at the equator
centrioles reach the two poles
Spindle fibres attach to the centromeres and pulls to arrange them
Anaphase
Mitosis
Chromatids pull apart to opposite ends of the cell
The centromeres divide and spindle fibres contract and shorten to pull them apart
Centromere leads
Telophase
Mitosis
Nuclear envelope reforms around chromosomes as the chromatids have now reached the poles.
The nucleus reappears and the chromosomes uncoil to form chromatin
Cytokinesis
Cytoplasm divides into two each containing a full set of chromosomes
ANIMALS: Furrows a cleavage by starting at the edge
PLANT: Forms a cell plate and starts from the middle
Importance of Mitosis
- Asexual reproduction
- Growth of multicellular organisms
- Repair to replace damaged cells
- Replace the blood cells broken down in the liver
Purpose of Checkpoints
- Prevent uncontrolled division
- Detect and repair damage to DNA
- Ensure cycle doesn’t reverse
- DNA only copied once
G2 Checkpoint
Checks cell size, DNA replication and that theres no damage
G1 Checkpoint
Checks cell size, Nutrients, Growth factors, DNA damage
G0 Checkpoint
Resting phase where cells leave permanently or temporarily
Cell differentiation to specialise them
Check for DNA damage
Lymphocytes can start dividing again and re enter cycle
Mitosis in Plants
Takes place in the meristem regions, just behind the root tips and shoot tips, the cambium and in the buds.
No centrioles present just the cell plate
Mitosis in Yeast Cells
Known as Budding
The nucleus divides by mitosis and the cell swells on one side creating an uneven distribution of cytoplasm.
The cell wall forms and so do two genetically identical cells
Mitosis in Prokaryote Cells
Known as binary fission
The cell grows to its limit then DNA begins to replicate
The two loops of DNA are pulled to opposite ends of the cell
This divides into two cells and a new wall forms
Stem Cells
Undifferentiated Cells that can differentiate into specialised ones
Totipotent Cell
Has the potential to develop into any type of cell found in the human body
Pluripotent Cell
Stem cells that develop the 3 primary germ layers
Multipotent cells
Thy can develop into more than one cell type, limited to adult stem cells and cord blood cells