21) Miscellaneous Bacterial Agents of Disease Flashcards
Spirochetes are human pathogens that are gram_______
negative
Spirochetes are not primary pathogens, majority are free living saprobes or commensals of…?
animals
Three types of spirochetes are
- Treponema
- Leptospira
and. ..
Borrelia
Treponema pallidum is a gram-negative spirochetes that causes the STD…..?
Syphilis “the great pox”
Treponema pallidum has 3 stages which are…?
primary syphilis
secondary syphilis
tertiary syphilis
Primary syphilis causes an appearance of _____ at the inoculation site.
chancre
Fluid from a primary syphilis chancre is highly contagious and heals spontaneously and moves into?
blood
Primary Syphilis has a latent period of ___weeks - _____months
3 weeks - 6 months
Secondary syphilis spirochete multiplying in the?
bloodstream
With secondary syphilis a rash forms on skin, palms soles with fever, headache and sore throat, but then disappears ________.
spontaneously
Secondary syphilis has a latent period of several years to _____ years
8
If Treponema pallidum/ syphilis is left untreated _____ syphilis forms
tertiary
Tertiary syphilis damages multiple tissues and _______.
Organs
Tertiary syphilis may cause _______ to develop.
Gummas (soft, tumor-like growth of the tissues (granuloma))
Neurosyphilis syphilis can involve the nervous system, but particularly the blood vessels in the brain, cranial nerves, and dorsal root of the spinal cord, causing diverse symptoms: severe headaches, convulsions, mental derangement, atrophy of the optic nerve, blindness and the _______pupil
Argyll-Roberston pupil
Argyll-Roberston pupil is _______
irregularly shaped
Neurosyphilis also cause cardiovascular syphilis that infects of the small vessels supplying the heart and aorta, compromising blood flow, resulting in heart failure or_____?
aortic aneurysm
Treponema pallidum(Congenital Syphilis) can pass in any three trimesters of pregnancy, most common in second and third. The pathogen inhibits fetal growth and disrupts critical periods of development with varied consequences from mild to ___________
miscarriage or still birth
Treatment for all forms of syphilis is what antibiotic?
Penicillin
Leptospira interrogans is a zoonosis associated with wild animals such as: racoons, foxes, skunks, rodents; also horses, dogs, cattle, and pigs, and it causes what disease?
leptospirosis
leptospirosis is transmitted by contact with animal….?
urine, skin abrasions or mucous membrane
Symptoms of Leptospira interrogans are high fever, chills, headache, muscle aches, conjunctivitis, and vomiting, diarrhea, rash and cause kidney disease, hepatic disease, jaundice and?
meningitis
Treatment for Leptospira interrogans is the antibiotic _____?
Penicillin
Does Leptospira interrogans have a vaccine for humans or animals?
Animals
The Genus Borrelia is transmitted by what vector?
arthropod
Borrelia hermsii is transmitted my tics but is reserved in squirrels and ?
chipmunks
Borrelia hermsii causes relapsing fever by the parasite changing antigens and the immune system responds ______
Over and over
Borrelia hermsii causes damage to what organs?
Liver, spleen, heart, kidneys, and cranial nerves.
Treatment for Borrelia hermsii is the anibiotic…?
doxycycline
Borrelia burgdorferi causes Lyme disease from what insect?
Tick