201 - 300 super exams Flashcards
You wanted to investigate if a new drug can prevent hemorrhagic strokes in hypertensive patients. The most appropriate study to perform is:
A. Clinical trial
B. Cross-sectional
C. Prospective cohort
D. Case-control
E. Retrospective cohort
A. Clinical trial
Clinical trials are prospective studies in which an intervention is applied.
Which correctly describes infant mortality?
A. Number of deaths in the first 28 days of life per 1000 live births in 1 year
B. Number of fetal deaths plus deaths in the first week of life per 1000 total births in 1 year
C. Number of deaths under the age of 1 year per 1000 live births in 1 year
D. Number of deaths between the ages of 28 days and 11 months per 1000 live births in 1 year
E. Number of deaths within 72 hours of life per 1000 live births in 1 year
C. Number of deaths under the age of 1 year per 1000 live births in 1 year
A new test for Salmonella infetion is introduced. Half of the patients who are tested have a positive test. Compared with blood cultures, 60% of those with a positive test are infected with Salmonella, and 80% of those who tested negative are free of the infection. What is the sensitivity of the new test?
A. 40%
B. 60%
C. 67%
D. 75%
E. 80%
D. 75%
The incidence rate of a disease is expressed as:
A. Number of cases observed
B. Number of new cases observed
C. Number of asymptomatic cases
D. Person-years of observation
E. Persons lost to follow-up
D. Person-years of observation
Person-years of observation simulatenously take into account the number of persons under observation and the duration of observation of each person.
A randomized study of breast conservation surgery to prevent recurrence in patients with stage I breast cancer fails to find a significant difference between BCS and control groups after ten years (N = 500 per group; p = 0.20). Which of the following might best explain this?
A. Misclassification bias
B. Type I error
C. Type II error
D. Selection bias
E. Ecologic fallacy
C. Type II error
Which patient is most likely to become a chronic carrier following an acute episode of hepatitis B?
A. A newborn
B. A 20 year-old female following vaginal sexual
transmission
C. A 50 year-old male following rectal sexual transmission with a partner positive for HBeAg
D. A 30 year-old health care worker following a percutaneous injury
E. A 40 year-old HIV-infected male with a CD4 count of 200
A. A newborn
Which hepatitis profile is consistent with a recently vaccinated adult?
A. HbsAg-positive, (+) IgM anti-HBcAg, (-) anti-HBsAg
B. HbsAg-negative, (-) IgM anti-HBcAg, (+) anti-HbsAg
C. HbsAg-positive, (+) IgM anti-HBcAg, (+) anti-HBsAg
D. HbsAg-negative, (-) IgM anti-HbcAg, (-) anti-HBsAg
E. HbsAg-positive, (+) IgM anti-HBcAg, (-) anti-HBsAg
B. HbsAg-negative, (-) IgM anti-HBcAg, (+) anti-HbsAg
A causative agent’s virulence is described as:
A. Development of neutralizing antibodies after an attack
B. Development of disease in infected persons
C. Death among cases
D. Infection among contacts of infected persons
E. Period of time from infection to appearance of signs and symptoms
C. Death among cases
__________ refers to the severity of illness produced by a microbe and is measured by the percentage of severe or fatal cases.
Virulence
Campylobacter jejuni is associated with which of the following conditions?
A. Guillain-Barre syndrome
B. Hemolytic anemia
C. Febrile seizures
D. Intussusception
E. Neutropenia
A. Guillain-Barre syndrome
Paragonimiasis is transmitted by ingestion of infected:
A. Swine
B. Fish
C. Cattle
D. Crab
E. Snail
D. Crab
The larval stages of Paragonimus wetsermanii, also known as the lung fluke, develop in freshwater crabs and other crustacea.
A 45 year-old male textile worker came in for an annual physical examination. He has no subjective complaints. He has been working in the same factory for 25 years. He is involved in the dye preparation. Which test should you request for this patient?
A. Chest x-ray
B. Urinalysis
C. Brain MRI
D. CBC with platelet count
E. Thyroid function test
B. Urinalysis
Dye workers are susceptible to bladder cancer due to exposure to B-naphtylamine and benzidine. Hematuria, gross or microscopic, is the most common presenting symptom.
A patient with silicosis is most susceptible to have:
A. Lung cancer
B. Pneumonia
C. Asbestosis
D. Mesothelioma
E. Tuberculosis
E. Tuberculosis
- It is postulated that silicosis results in a depression of cell-mediated immunity, and crystalline silica may inhibit the ability of pulmonary macrophages to kill phagocytosed mycobacteria.
Which metal may cause Fanconi syndrome if exposure has been chronic?
A. Arsenic
B. Lead
C. Mercury
D. Cadmium
E. Zinc
D. Cadmium
The antidote to parathion poisoning is:
A. EDTA
B. Pralidoxime
C. Dimercaprol
D. Acetylcysteine
E. Flumazenil
B. Pralidoxime
- Parathion is an organophosphate pesticide.
The Ames test is applied in:
A. HIV testing
B. Mutagenicity screening
C. Diagnosis of bacterial vaginosis
D. Statistical analysis in clinical trials
E. Peripheral vision testing
B. Mutagenicity screening
- The Ames test is a bacterial mutation assay that is most commonly used in the rapid screening test for mutagenesis and carcinogenesis. It is very sensitive to DNA damage.
A patient with pulmonary tuberculosis has just finished 2 months of intensive therapy. He complains of numbness of both hands. This would have been prevented by co- administration of which vitamin?
A. Thiamin
B. Riboflavin
C. Ascorbic acid
D. Pyridoxine
E. Folic acid
D. Pyridoxine
- Isoniazid causes peripheral neuropathy. Vitamin B6 is given to prevent this adverse drug effect.
The use of oral contraceptives will have the most impact on gynecological mortality by reducing the risks for which of the following cancers?
A. Ovarian
B. Breast
C. Cervical
D. Uterine
E. Vulvar
A. Ovarian
- OCPs decrease the risk of ovarian cancer by up to 80%. They can also reduce the risk of uterine cancer.
Screening for hypertension constitues:
A. Primary prevention
B. Secondaryprevention
C. Tertiary prevention
D. A and B
E. B and C
D. A and B
To obtain informed consent, which of the following is NOT required?
A. Disclosure of the nature and purpose of the proposed therapy
B. Disclosure of the risks and benefits of the proposed therapy
C. Alternatives to the proposed therapy
D. Consequences if the proposed therapy is not given
E. Signature of the patient on the written consent form
E. Signature of the patient on the written consent form
In the case of Tarasoff v. Regents of the University of California (1976), a person was murdered after a therapist failed to inform the victim of a patient’s intentions to kill that person. This exemplifies:
A. Malpractice
B. Duty to warn
C. Confidentiality
D. Respect for autonomy
E. Nonmaleficence
B. Duty to warn
- The court held that the patient’s right to privacy did not obviate the therapist’s duty to warn possible victims in cases in whhich a therapist can reasonably determine that another person is at foreseeable risk.
This type of family includes step parents, and or step children brought about by annulmentm with separation and remarriage?
A. Nuclear
B. Communal
C. Extended
D. Blended
E. None of the above
D. Blended
- Nuclear - married man and women with their children, extended - linked together by virtue of kinship bond between parents and children and or between siblings . It ncludes three generations.
*Communal - composed of group of individual who are formed for specific ideological or societal purposes.
In a five star physician model, which aspect refers to a physician referring a patient to other specialist, or to agencies and institution and coodinates function in the clinic, hospital or community center?
A. Social mobilizer
B. Health care provider
C. Manager
D. Counselor
E. Researcher
C. Manager
Emprovers and motivates patient, family and even the community to be partners in health care
Social mobilizer
Promotes healthy lifestyle by empathic explanation and encouraging individuals and groups to enhance and protect their health.
Counselor
Considers patient as an integral part of a family and the community and provides high standard clinical care and personalizes preventive care within a long term trusting relationship
Health care provider
Selects appropriate medicine,test or ancillary procedures based on evidenced based practice.
Researcher
T his type of nonverbal communication connotes that the physician wants to establish a sense of personal relationship with the patient?
A. Eye contact
B. posture
C. Handshake
D. Tone of voice
E. mannerism
C. Handshake
In what phase in the family life cycle wherein there is development of adult to adult relationship between grown up children and their parents?
A. Launching family
B. Family with adolescents
C. Family in later life
D. Unattached young adult
E. none of the above
A. Launching family
launching family - this stage begins when the first child leaves home. During this stagem the parents must develop adult type relationships between the grown up children and themselves.
In the family illness trajectory, what stage refers to the second crisis which points to the family’s adjustment to the effect of illness?
A. Major therapeutic effect
B. Reaction to diagnosis
C. Adjustment to the permanency of the outcome
D. early adjustment to outcome
E. onset of illness
D. early adjustment to outcome
In family APGAR, this refers to the capabillity of the family to utilize and share inherent resources:
A. Adaptation
B. partnership
C. Growth
D. Affection
E. Resolve
A. Adaptation
Sharing in decision making. Measure the satisfaction attained in solving problems by communicating.
Partnership
Refers to both physical and emotional growth. This measures the satisfaction of the available freedom of change.
Growth
Measures the members satisfaction with the intimacy and emotional interaction that exist in the family.
Affection
Refers to how time, space, and money are shared. measures the members satisfaction with the commitment made by other members of the family.
Resolve
In McCubbins family typology, this type of regenerative family has a high value in family coherence but low in terms of family hardiness?
A. Vulnerable type
B. Durable type
C. Secure type
D. Regenerative type
E. None of the above
B. Durable type
Low family hardiness, low family coherence. ( more complacent , less likely to try new and exciting things, tending to do the same things over and over, and are less likely to encourage each other to be active and to learn new things
Vulnerable type
High family hardiness, low family coherence. active, in control, but when faced with difficulties are also less supportive of each other, less caring and loyal. and less tolerant of hardships.
Secure type
High in family hardiness and coherence. cope by working together to solve problems.
Regenerative type
In what phase of clinical trial wherein the drug or test is performed on patients with consent carried out mostly on hospital in patients. It assesses the effectiveness, safety and continued use of the drug device?
A. Phase 1
B. Phase 2
C. Phase 3
D. Phase 4
E. Phase 5
C. Phase 3
Experimental animals used to establish that the new agent is effective and suitable for human use.
Phase 1
Assess the effectiveness of the drug or device, determines the appropriate dose and investigates its safety.
Phase 2
Trial in normal field or program setting, reassess effectiveness, safety, acceptability and continued use of the drugs.
Phase 4
Which of the following is a criteria for instituting a screening program?
A. There should be a short period between first signs and overt disease
B. Diagnostic test must be sensitive and specific
C. Low prevalence during the preclinical stage of the disease
D. all of the above
E. none of the above
B. Diagnostic test must be sensitive and specific
What type of epidemiologic study is useful for investigating exposures that are fixed characteristics of individuals, such as ethnicity, socioeconomic status and blood groups, or chronic disease or stable condition?
A. Prevalence studies
B. Case control studies
C. prospective cohort studies
D. RCT
E. Ecological studies
A. Prevalence studies
Which of the following best describes the double burden of the disease in the Philippines?
A. Pneumonia is the leading communicable cause of mortality and morbidity
B. The leading cause of mortality is cardiovascular disease
C. hypertension is the 5th leading cause of morbidity in this country
D. all of the above
E. none of the above
D. all of the above