2- sexual reproduction in mammals Flashcards

1
Q

order of oogenesis

A

oogonia -> primary oocytes -> first meiotic division -> second meiotic division -> completion of meiosis -> polar bodies

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2
Q

oogenesis- oogonia

A

primordial germ cells divide by mitosis to form oogonia during the foetal period

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3
Q

oogenesis- primary oocytes

A
  • each oogonium grows and becomes a primary oocyte
  • the primary oocyte enters prophase of the first meiotic division but halts
  • at birth, all primary oocytes are in a state of arrested development until puberty
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4
Q

oogenesis- first meiotic division

A

at the start of each menstrual cycle, one primary oocyte resumes its first meiotic division to form a secondary oocyte and a small polar body

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5
Q

oogenesis- second meiotic division

A
  • the secondary oocyte enters metaphase of the second meiotic division but halts
  • the secondary oocyte is released at ovulation
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6
Q

oogenesis- competition of meiosis

A
  • when fertilisation occurs, the secondary oocyte resumes its second meiotic division to form the ovum and another polar body
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7
Q

oogenesis- polar bodies

A
  • they are small cells that eventually degenerate
  • they serve to discard the extra set of chromosomes
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8
Q

spermatogenesis- spermatogonia

A

primordial germ cells divide by mitosis to form spermatogonia

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9
Q

spermatogenesis- primary spermatocytes

A

spermatogonia grow and become primary spermatocytes

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10
Q

spermatogenesis- first meiotic division

A

primary spermatocytes enter the first meiotic division to form secondary spermatocytes

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11
Q

spermatogenesis- second meiotic division

A
  • secondary spermatocytes enter the second meiotic division to form spermatids
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12
Q

spermatogenesis- maturation

A
  • spermatids differentiate and grow to form mature spermatozoa
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13
Q

polar body

A
  • small cells that bud off from an oocyte which eventually degenerate
  • they serve to discard the extra set of chromosomes
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14
Q

gonad

A

the organ that produces gametes

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15
Q

germinal epithelium

A

an epithelium consisting of a single layer of primordial germ cells that undergoes mitosis to produce other cells

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16
Q

primordial germ cells

A

the primary undifferentiated germ cell type that differentiates into germ cells and give rise to gametes through meiosis

17
Q

oogenesis diagram

18
Q

spermatogenesis diagram

19
Q

events of fertilisation order

A

initial contact -> acrosome reaction -> enzyme release -> membrane fusion -> entry of sperm nucleus -> cortical reaction -> competition of meiosis II -> nuclear fusion

20
Q

fertilisation- initial contact

A

glycoproteins on the sperms cell membrane and the eggs zona pellucida interact

21
Q

fertilisation- acrosome reaction

A

the acrosome reaction is triggered. it fuses with the sperms cell membrane

22
Q

fertilisation- enzyme release

A

the acrosome releases hydrolytic enzymes, which help digest the zona pellucide

23
Q

fertilisation- membrane fusion

A

the sperms cell membrane and the eggs cell membrane fuse together

24
Q

fertilisation- entry of sperm nucleus

A

the sperm nucleus enters the egg

25
Q

fertilisation- cortical reaction

A

the cortical reaction is triggered, cortical granules in the egg fuse with the cell membrane and release enzymes that harden the zona pellucida to prevent polyspermy

26
Q

fertilisation- competition of meiosis II

A

the egg completes the second meiotic division

27
Q

fertilisation- nuclear fusion

A

the haploid nuclei of the sperm and ovum to form a diploid nucleus- a zygote

28
Q

egg diagram

29
Q

sperm diagram

30
Q

corona radiata

A

follicle cells that form a protective coating around the oocyte

31
Q

zona pellucida

A
  • protective coating that the sperm has to penetrate through for fertilisation to occur
  • prevents polyspermy
32
Q

cortical granules

A

releases substances which causes the zona pellucida to harden, forming a rough fertilisation membrane

33
Q

nucleus - egg

A

haploid so a full set of chromosomes is restored at fertilisation

34
Q

acrosome

A

contains digestive enzymes which break down the zona pellucida and allow sperm to penetrate the egg

35
Q

nucleus- sperm

A

haploid, so a full set of chromosomes is restored at fertilisation

36
Q

mitochondria

A

provide energy for rotation of the flagella allowing the cell to move

37
Q

centriole

A

the centriole is contributed to the zygote to allow it to undergo cell division

38
Q

flagella

A

allows the sperm to swim towards the oocyte

39
Q

early development of the embryo to blastocyst stage

A

1) the zygote undergoes mitosis as it moves through the fallopian tube towards the uterus
2) blastomere cells are formed
3) by day 3-4, a morula (solid ball of 16 blastomeres) is formed, it reaches the uterus
4) by day 5-9 a blastocyst (ball is filled with fluid) is formed, cell differentiation begins.
5) the trophoblasts (outer layer of cells) form the amnion, placenta and extraembryonic tissues
6) the inner cell mass (blastomeres) form the embryo