2. Inflammation Flashcards

1
Q

Inflammation

List

A
Define
Signs
Types
Initiation
Acute 
Chronic
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2
Q

Inflammation

List

A
Define
Signs
Types
Initiation
Acute 
Chronic
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3
Q

Inflammation

Define

A

Local response to injury live cells mammalian

Limit spread of injurious agent

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4
Q

Inflammation

Signs

A
Celsus
Rubor
Tumor
Calor
Dolor
Functio laesa galen
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5
Q

Acute inflammation

List

A
Vascular event
Cellular events
Chemical mediators
Cells
Morphology
Systemic effects
Outcome
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6
Q

Chronic inflammation

Types

A

Non specific

Granulomatous

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7
Q

Chronic granulomatous inflammation

A

Evolution of granuloma

Morphology of granuloma

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8
Q

Evolution of granuloma

A

Engulfment macrophages
Cd4+ t cells
Cytokines

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8
Q

Outcomes of acute inflammation

A

Agent removed

No tissue liss

Resolution
Regeneration

With tissue loss

Fibrosis

Agent persists

Discharge pus

Supparation

Recurrence

Chronic inflammation

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9
Q

Morphology of granuloma

A
Epithelioid cells
Multinucleate giant cell
Lymphoid cell
Necrosis
Fibrosis
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10
Q

Vascular events

A
Haemodynamic change
  Transient vasoconstriction
   Persistent progressive vasodilation
   Elevation of local hydrostatic pressure
   Slowing or stasis
   Leucocyte migration
Lewis triple response
   Red line
   Flare
   Wheal
Altered vascular permeability
    Starling hypothesis
    Outward movement
    Inward movement
Mechanical of vascular leakiness
   Contraction of endothelial cells
    Contraction or mild endothelial damage
    Direct injury
    Leucocyte pmns mediated endorsed injury
    Transcytosis across endorsed cytoplasm
    Leakiness in neovascularization
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11
Q

Cellular events

A

Exudation of leukocytes

Normal axial flow
Margination and pavementing
Rolling and adhesion ceoll adhesion molecules selecins p e l integrins
Transmigration
Chemotaxis

Phagocytosis

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12
Q

Mediators of inflammation

A

.

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