2 - HPV and Cervical Cancer

Question 1

2 most important cancer and warts causing HPVs

Answer 1

cancer - 16, 18

warts - 6, 11

Question 2

part of cervix that is most vulnerable to dysplasia

Answer 2

transformation zone - between original and new squamocolumnar jxns

Question 3

colposcopy

Answer 3

microscope used to visualize cervix during exam, usually put acetic acid on cervix to help identify lesions

Question 4

ASCUS in pap smear findings

Answer 4

atypical squamous cells of undetermined significance

Question 5

sensitivity of pap smears

Answer 5

~60%

Question 6

CIN I through III

Answer 6

cervical intraepithelial neoplasia
1 - inner 1/3 only involved
3 - full thickness involvement
2 - somewhere in between ~1/2

1 can be observed and not actively treated - many regress spontaneously and few turn into aggressive dz

Question 7

MC gynecological cancer worldwide

Answer 7

cervical cancer (3rd in US)

Question 8

MC histology type of cervical cancer

Answer 8

squamous (80%)