14 - Uterus Path Flashcards
1
Q
what genetic mutation is assoc w/ benign hyperplasia of endometrium?
A
inactivation of PTEN tumor suppressor
2
Q
which is a more favorable type of endometrial CA - endometrioid or papillary serous
A
endometrioid - caught at early stage and good prognosis
3
Q
malignant mixed mullerian tumors of uterus
A
malignant glands and stroma
only 2-5% of uterine malignancy, but poor prognosis
seen in postmenopausal women
4
Q
origin of complete hydatidiform mole
A
fertilization of empty ovum - usually by one sperm whose chromosomes duplicate to make a diploid cell w/ no maternal DNA and no p57
5
Q
how does a partial hydatidiform mole form?
A
union of oocyte w/ 2 sperm. Triploid and p57 pos
