17&18 - Urologic Malignancy Flashcards
who is prostate cancer worst in?
african americans - presents at later stage, worse prognosis
PSA levels cutoffs
1-2.5, retest annually
>2.5, biopsy
gold standard prostate CA tx in relatively younger pt
surgery - need high radiation dose so the long term side effects of that are much worse, and you get impotent over time from radiation anyway
risk factors for bladder CA
male
smoking
occupational exposures (leather, rubber, dyes)
schistosomiasis
MC type of bladder cancer
transitional cell CA (TCC)
mitomycin C
intravesicular chemo agent for bladder cancer
major contraindication to getting cisplatin
nephrotoxicity - can’t have low GFR
main tx modality for kidney CA
surgery - not very radio or chemosensitive
chemo for bladder CA
MVAC - methotrexate, vinblastine, doxorubicin, cisplatin