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Pharmacology > 2- ANS > Flashcards

2- ANS Flashcards

1
Q

Botulinum toxin is used in ?

A 
Blepharospasm 
Strabismus 
Hyperhidrosis 
Dystonia 
Cosmetics
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2
Q

The sphincter that contracts in response to parasympathetic activation ?

A

Lower esophageal sphincter

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3
Q

Use of Bethanechol ?

A

Ttt of ileus and urinary retention

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4
Q

Use of Methacholine ?

A

Diagnosis of bronchial hyperactivity

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5
Q

Use of Pilocarpine and Cevimeline ?

A

ttt of xerostomia and glaucoma

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6
Q

Use of Edrophonium ?

A

Diagnosis of myathenia gravis

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7
Q

Use of Physostigmine ?

A

ttt of glaucoma

Antidote in atropine overdose

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8
Q

Use of Neostigmine and Pyridostigmine ?

A

Ttt of
Ileus
Urine retention
Myasthenia gravis

Reversal of nondepolarizing NM blockers

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9
Q

Use of Donepezil and Rivastigmine ?

A

Ttt of Alzheimer disease

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10
Q

Drug used to regenerate AChE ?

A

Pralidoxime ( 2-PAM )

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11
Q

Drugs with anti muscarinic pharmacology ?

A 
1- antihistamines 
2- TCA 
3- antipsychotics 
4- quinidine 
5- amantadine 
6- meperidine
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12
Q

Use of scopolamine ?

A

Ttt of motion sickness

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13
Q

Use of Benztropine and Trihexphenidyl ?

A

Ttt of Parkinsonism and acute extrapyramidal symptoms induced by antipsychotics

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14
Q

Use of Oxybutynin ?

A

Ttt of overactive bladder ( urge incontinence )

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15
Q

Nicotinic receptor antagonists?

A

Hexamethonium

Mecamylamine

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16
Q

Example for alpha 1 agonist and its use ?

A

Phenylephrine

Nasal decongestant
Ophthalmologic use ( causes mydriasis without cycloplegia )
In hypotensive states

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17
Q

Examples for alpha 2 agonists ? Their use ?

A

Clonidine
Methyldopa

In mild to moderate hypertension

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18
Q

Example for non selective beta agonist ?

A

Isoproterenol

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19
Q

Example for selective beta 1 agonist ? Its use ?

A

Dobutamine

In CHF

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20
Q

Example for selective beta 2 agonists ? Their use ?

A

Salmetrol , albuterol , terbutaline —> in asthma

Terbutaline —> in premature labour

21
Q

Examples for NE releasers ?

A

Tyramine in red wine and cheese
Amphetamines as methylphenidate —> in narcolepsy and ADHD
Ephedrine —> cold medication

22
Q

Examples for NE reuptake inhibitors ?

A

Cocaine

TCA

23
Q

MOA - A present in ? Metabolizes what ?

A

Liver

NE
5-HT
Tyramine

24
Q

MOA-B resent in ? Metabolizes what ?

A

Brain

Dopamine

25
Q

Non selective alpha blockers ?

A

Phentolamine ( competitive inhibitor )

Phenoxybenzamine ( non competitive inhibitor )

26
Q

Selective alpha 1 blockers examples ?

A

Prazosine
Doxazosine
Terazosine
Tamsulosine

27
Q

Selective alpha 2 blocker ? Its use ?

A

Mertazapine

As antidepressant

28
Q

Beta blockers that have ISA and don’t increase blood lipids ?

A

Acebutolol

Pindolol

29
Q

Selective beta1 blockers ?

A

Acebutolol
Atenolol
Metoprolol

30
Q

Beta blocker that doesnot have sedation effect ?

A

Atenolol

31
Q

Examples for drugs that have combined alpha 1 and beta blocking activity ? Their use ?

A

Carvedilol —> CHF

Labetalol —> hypertensive emergencies

32
Q

Drug that have K channel blockade and beta blocking activity ?

A

Sotalol

33
Q

Example for alpha 1 agonist and its use ?

A

Phenylephrine

Nasal decongestant
Ophthalmologic use ( causes mydriasis without cycloplegia )
In hypotensive states

34
Q

Examples for alpha 2 agonists ? Their use ?

A

Clonidine
Methyldopa

In mild to moderate hypertension

35
Q

Example for non selective beta agonist ?

A

Isoproterenol

36
Q

Example for selective beta 1 agonist ? Its use ?

A

Dobutamine

In CHF

37
Q

Example for selective beta 2 agonists ? Their use ?

A

Salmetrol , albuterol , terbutaline —> in asthma

Terbutaline —> in premature labour

38
Q

Examples for NE releasers ?

A

Tyramine in red wine and cheese
Amphetamines as methylphenidate —> in narcolepsy and ADHD
Ephedrine —> cold medication

39
Q

Examples for NE reuptake inhibitors ?

A

Cocaine

TCA

40
Q

MOA - A present in ? Metabolizes what ?

A

Liver

NE
5-HT
Tyramine

41
Q

MOA-B resent in ? Metabolizes what ?

A

Brain

Dopamine

42
Q

Non selective alpha blockers ?

A

Phentolamine ( competitive inhibitor )

Phenoxybenzamine ( non competitive inhibitor )

43
Q

Selective alpha 1 blockers examples ?

A

Prazosine
Doxazosine
Terazosine
Tamsulosine

44
Q

Selective alpha 2 blocker ? Its use ?

A

Mertazapine

As antidepressant

45
Q

Beta blockers that have ISA and don’t increase blood lipids ?

A

Acebutolol

Pindolol

46
Q

Selective beta1 blockers ?

A

Acebutolol
Atenolol
Metoprolol

47
Q

Beta blocker that doesnot have sedation effect ?

A

Atenolol

48
Q

Examples for drugs that have combined alpha 1 and beta blocking activity ? Their use ?

A

Carvedilol —> CHF

Labetalol —> hypertensive emergencies

49
Q

Drug that have K channel blockade and beta blocking activity ?

A

Sotalol

Pharmacology (9 decks)

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